Journal ArticleDOI
Cylindrospermopsin: a potent hepatotoxin from the blue-green alga Cylindrospermopsis raciborskii
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This article is published in Journal of the American Chemical Society.The article was published on 1992-09-01. It has received 534 citations till now. The article focuses on the topics: Cylindrospermopsis raciborskii & Cylindrospermopsis.read more
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Photocatalytic degradation of cylindrospermopsin under UV-A, solar and visible light using TiO2. Mineralization and intermediate products.
TL;DR: TOC and inorganic ions determinations suggested that complete mineralization of CYN was achieved under UV-A in the presence of Degussa P25, and hydroxyl radical attack is the main mechanism followed.
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Time-dependent histopathological changes induced in Tilapia (Oreochromis niloticus) after acute exposure to pure cylindrospermopsin by oral and intraperitoneal route
Daniel Gutiérrez-Praena,Ángeles Jos,Silvia Pichardo,Rosario Moyano,Alfonso Blanco,J. G. Monterde,Ana M. Cameán +6 more
TL;DR: Tilapia were exposed for the first time to an acute dose of CYN by intraperitoneal (i.p.) injection, and the effects were compared with the oral route (gavage), supporting the histopathological results obtained in these organs.
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Extreme differences in akinete, heterocyte and cylindrospermopsin concentrations with depth in a successive bloom involving Aphanizomenon ovalisporum (Forti) and Cylindrospermopsis raciborskii (Woloszynska) Seenaya and Subba Raju
TL;DR: This is the first field study to provide evidence that C. raciborskii, despite being traditionally considered a tropical species, can be highly toxic in cooler waters especially when accompanied by strong stratification involving an anoxic semi-saline hypolimnion.
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Cytotoxic and genotoxic effects of cylindrospermopsin in mice treated by gavage or intraperitoneal injection
Emmanuelle Bazin,Sylvie Huet,Gérard Jarry,Ludovic Le Hégarat,John S. Munday,Andrew R. Humpage,Valérie Fessard +6 more
TL;DR: Evaluation of CYN‐induced in vivo DNA damage in mice using alkaline comet assay (ACA) and micronucleus assay (MNA) concomittantly found significant DNA damage was detected within the colon by ACA and DNA breaks and chromosome damage were significantly increased by MMS in all the organs evaluated.
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The first identification of the rare cyanobacterial toxin, homoanatoxin-a, in Ireland
TL;DR: Application of the fluorimetric LC protocol to examine cyanotoxins in 20 Irish lakes resulted in the detection of homoanatoxin-a at four locations and confirmation of toxin identity was achieved by chromatographic and mass spectral comparison with authentic toxin isolated from a laboratory clone culture of Planktothrix (formerly Oscillatoria formosa).