"Cytoplasmic" DNA from primary embryonic cell cultures is not informational.
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The results rule out the possibility that this nuclear DNA fraction in primary embryonic cell cultures has an informational role, as it contains all rather than a selection of the information in the cell genome.About:
This article is published in FEBS Letters.The article was published on 1972-01-15 and is currently open access. It has received 11 citations till now. The article focuses on the topics: Nuclear DNA & Reannealing.read more
Citations
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Journal ArticleDOI
Localization and Quantification of Circular DNA in Yeast
TL;DR: It is concluded from the cytoplasmic location of oDNA that it does not represent a gene amplification product nor is it related to “informosomal” DNA.
Journal ArticleDOI
Physical properties of cytoplasmic membrane-associated DNA.
TL;DR: Sheared, denatured cytoplasmic membrane-associated DNA reassociates as two distinct fractions whose rates of reassociation differ by about four decades: the complexity of the reassociation of this DNA tends to rule out the possibility that it arises from either mycoplasmal or viral contamination of cell cultures.
Journal ArticleDOI
The problem of cytoplasmic DNA: its extrusion/uptake by cultured cells and its possible role in cell-cell information transfer.
Journal Article
Pathways of nucleocytoplasmic translocation of ribonucleoproteins.
Werner W. Franke,Ulrich Scheer +1 more
TL;DR: The eukaryote structure is transitory and dynamic since it can be transitorily disintegrated, without harming the viability of the cell, as for example in some cell cycle stages of those cells which have an 'open' mitosis and meiosis as well as in special cell or nuclear differentiation processes such as in sperm development and in pronuclei formation.
References
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Repeated Sequences in DNA
Roy J. Britten,D. E. Kohne +1 more
TL;DR: Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms and used in medicine, science, and engineering.
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Gene Regulation for Higher Cells: A Theory
Roy J. Britten,Eric H. Davidson +1 more
TL;DR: Direct support for the idea that regulation of gene activity underlies cell differentiation comes from evidence that much of the genome in higher cell types is inactive and that different ribonucleic acids are synthesized in different cell types.
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Nucleic acid reassociation in formamide.
TL;DR: The present study explores in detail the relationships among the rate and specificity of reaction, the temperature, and the concentrations of formamide and salt.
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Separation of murine cellular and murine leukaemia virus DNA polymerases.
TL;DR: The DNA polymerase of murine leukaemia virus has been purified and can be separated physically from enzymes with some similar properties that are present in normal cells.
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Reiteration and Clustering of DNA Sequences Complementary to Histone Messenger RNA
TL;DR: The DNA complements of 9S messenger RNA thought to code for histones in sea urchins are reiterated, closely clustered, relatively stable in evolution and development and potentially separable from other nuclear DNA.