Developmental Connectomics from Infancy through Early Childhood
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TLDR
Five fundamental principles of brain network development during the critical first years of life are highlighted, emphasizing strengthened segregation/integration balance, a remarkable hierarchical order from primary to higher-order regions, unparalleled structural and functional maturations, substantial individual variability, and high vulnerability to risk factors and developmental disorders.About:
This article is published in Trends in Neurosciences.The article was published on 2017-08-01 and is currently open access. It has received 182 citations till now. The article focuses on the topics: Connectomics & Connectome.read more
Citations
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Journal ArticleDOI
Imaging structural and functional brain development in early childhood
TL;DR: Initial evidence regarding the usefulness of early imaging biomarkers for predicting cognitive outcomes and risk of neuropsychiatric disorders is discussed.
Journal ArticleDOI
The UNC/UMN Baby Connectome Project (BCP): An overview of the study design and protocol development.
Brittany R. Howell,Martin Styner,Wei Gao,Wei Gao,Pew Thian Yap,Li Wang,Kristine R. Baluyot,Essa Yacoub,Geng Chen,Taylor M Potts,Andrew P. Salzwedel,Gang Li,John H. Gilmore,Joseph Piven,J. Keith Smith,Dinggang Shen,Kamil Ugurbil,Hongtu Zhu,Weili Lin,Jed T. Elison +19 more
TL;DR: The overall study protocol is provided, including approaches for subject recruitment, strategies for imaging typically developing children 0–5 years of age without sedation, imaging protocol and optimization, a description of the battery of behavioral assessments, and QA/QC procedures.
Journal ArticleDOI
The development of brain network hubs.
Stuart Oldham,Alex Fornito +1 more
TL;DR: A large number of brain regions are highly connected, acting as network hubs, and hub connectivity, especially of frontal areas, strengthens from birth to adulthood.
Journal ArticleDOI
Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission
Christopher Eccleston,Christopher Eccleston,Christopher Eccleston,Emma Fisher,Richard F. Howard,Rebeccah Slater,Paula Forgeron,Tonya M. Palermo,Kathryn A. Birnie,Brian J. Anderson,Christine T. Chambers,Geert Crombez,Gustaf Ljungman,Isabel Jordan,Zachary Jordan,Caitriona Roberts,Neil L. Schechter,Christine B. Sieberg,Dick Tibboel,Suellen M. Walker,Dominic Wilkinson,Chantal Wood +21 more
TL;DR: This work aims to demonstrate the power of informed consent and informed choice in the decision-making process to deliver transformative action in paediatric pain.
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Neural histology and neurogenesis of the human fetal and infant brain.
TL;DR: The microstructural organization and neural circuitry elements of the fetal and early postnatal human cerebrum are described and the genetic, genomic, and molecular biology data on phenotypic specification of developing brain regions, areas and neurons are included.
References
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Jonathan D. Power,Kelly Anne Barnes,Abraham Z. Snyder,Bradley L. Schlaggar,Steven E. Petersen +4 more
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