Diagnostic Accuracy of Bone Turnover Markers and Bone Histology in Patients With CKD Treated by Dialysis
Stuart M. Sprague,Ezequiel Bellorin-Font,Vanda Jorgetti,Aluizio B. Carvalho,Hartmut H. Malluche,Aníbal Ferreira,Patrick C. D'Haese,Tilman B. Drüeke,Hongyan Du,Thomas Manley,Eudocia Rojas,Sharon M. Moe +11 more
TLDR
In this paper, the parathyroid hormone (PTH) concentration was used to discriminate low from nonlow and high from nonhigh BFR/BS, with an area under the receiver operating characteristic curve > 0.70 but not more than 323.0pg/mL.About:
This article is published in American Journal of Kidney Diseases.The article was published on 2016-04-01 and is currently open access. It has received 194 citations till now. The article focuses on the topics: Renal osteodystrophy & Bone remodeling.read more
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KDIGO Clinical Practice Guideline on the evaluation and management of candidates for kidney transplantation
Steven J. Chadban,Curie Ahn,David A. Axelrod,Bethany J. Foster,Bertram L. Kasiske,Vijah Kher,Deepali Kumar,Rainer Oberbauer,Julio Pascual,Helen Pilmore,James R. Rodrigue,Dorry L. Segev,Neil S. Sheerin,Kathryn Tinckam,Germaine Wong,Gregory A. Knoll +15 more
TL;DR: The goal is to assist the clinical team to assimilate all data relevant to an individual, consider this within their local health context, and make an overall judgment on candidacy for transplantation.
Journal ArticleDOI
Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease–Mineral and Bone Disorder: Synopsis of the Kidney Disease: Improving Global Outcomes 2017 Clinical Practice Guideline Update
Markus Ketteler,Geoffrey A. Block,Pieter Evenepoel,Masafumi Fukagawa,Charles A. Herzog,Linda M. McCann,Sharon M. Moe,Rukshana Shroff,Marcello Tonelli,Nigel D Toussaint,Marc G. Vervloet,Mary B. Leonard +11 more
TL;DR: This synopsis focuses on diagnosis of CKDMBD and management of serum phosphate, calcium, and PTH levels in adults and areas in which controversy and knowledge gaps exist.
Journal ArticleDOI
Changing bone patterns with progression of chronic kidney disease
TL;DR: Evidence is provided that in early chronic kidney disease stages adynamic bone disease characterized by low bone turnover occurs first, at least in a significant proportion of patients, and FGF23 and Klotho play a direct role in the transition from low- to high-turnover bone disease.
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Fractures in patients with CKD—diagnosis, treatment, and prevention: a review by members of the European Calcified Tissue Society and the European Renal Association of Nephrology Dialysis and Transplantation
TL;DR: The literature related to the pathophysiological role of various mineral and biochemical factors involved in renal osteodystrophy, including sclerostin and fibroblast growth factor 23, are reviewed.
References
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Prevalence of Chronic Kidney Disease in the United States
Josef Coresh,Elizabeth Selvin,Lesley A. Stevens,Jane Manzi,John W. Kusek,Paul W. Eggers,Frederick Van Lente,Andrew S. Levey +7 more
TL;DR: The prevalence of CKD in the United States in 1999-2004 is higher than it was in 1988-1994 and this increase is partly explained by the increasing prevalence of diabetes and hypertension and raises concerns about future increased incidence of kidney failure and other complications.
Journal Article
K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease
Shaul G. Massry,Jack W. Coburn,Glenn M. Chertow,Keith A. Hruska,Craig B. Langman,Hartmut H. Malluche,Kevin J. Martin,Linda McCann,James T. McCarthy,Sharon M. Moe,Isidro B. Salusky,Donald J. Sherrand,Miroslaw Smogorzewski,Kline Bolton,Charles Turkelson,Karyn A. Tappe,Stephen Tregear,James Reston,Wendy Bruening,Mark Monteforte,Janice Kaczmarek,Vivian Coates,George R. Bailie,Bryan N. Becker,Gavin J. Becker,Jerrilynn D. Burrowes,Fernando Carrera,David N. Churchill,Allan J. Collins,Peter W. Crooks,Dick DeZeeuw,Thomas A. Golper,Frank A. Gotch,Antonio M. Gotto,Roger Greenwood,Joel W. Greer,Richard H. Grimm,William E. Haley,Ronald J. Hogg,Alan R. Hull,Lawrence G. Hunsicker,Cynda Ann Johnson,Michael J. Klag,Saulo Klahr,Norbert Lameire,Francesco Locatelli,Sally McCulloch,Maureen Michael,Joseph V. Nally,John M. Newmann,Allen R. Nissenson,Keith C. Norris,Gregorio T. Obrador,William F. Owen,Thakor G. Patel,Glenda Payne,Claudio Ronco,Rosa A. Rivera-Mizzoni,Anton C. Schoolwerth,Robert A. Star,Michael W. Steffes,Theodore I. Steinman,John Pierre Wauters,Nanette K. Wenger,Josephine P. Briggs,Thomas H. Hostetter,Garabed Eknoyan,Aderra Levin,Nathan W. Levin,Sharon Andreoli,Sally Burrows-Hudson,Derrick Latos,Donna Mapes,Edith Oberley,Brian J.G. Pereira,Nadine Ferguson,Donna Fingerhut,Anthony Gucciardo,Margaret Klette,Doreen Mallard,Kerry Willis +80 more
Journal Article
KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD)
Journal ArticleDOI
Definition, evaluation, and classification of renal osteodystrophy: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO)
Sharon M. Moe,Tilman B. Drüeke,John Cunningham,Wayne K. Goodman,Kevin J. Martin,Klaus Olgaard,Susan M. Ott,Stuart M. Sprague,Norbert Lameire,Garabed Eknoyan +9 more
TL;DR: It is recommended that the term renal osteodystrophy be used exclusively to define alterations in bone morphology associated with CKD, and the term CKD-Mineral and Bone Disorder (CKD-MBD) be used to describe a broader clinical syndrome that develops as a systemic disorder of mineral and bone metabolism due to CKD.