Effects of chemical pollution on the activities of hepatic xenobiotic metabolizing enzymes in fish from the river rhône
TLDR
This study clearly demonstrates a close relationship between PCB contamination and MO activities in fish from the field and thus clearly emphasizes the interest in MO as a monitoring tool for estimating water quality.About:
This article is published in Science of The Total Environment.The article was published on 1988-07-15 and is currently open access. It has received 85 citations till now. The article focuses on the topics: Rutilus.read more
Citations
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Fish bioaccumulation and biomarkers in environmental risk assessment: a review
TL;DR: There is little doubt that measurements of bioaccumulation and biomarker responses in fish from contaminated sites offer great promises for providing information that can contribute to environmental monitoring programs designed for various aspects of ERA.
Journal ArticleDOI
Ethoxyresorufin-O-deethylase (EROD) activity in fish as a biomarker of chemical exposure.
TL;DR: This review compiles and evaluates existing scientific information on the use, limitations, and procedural considerations for EROD activity (a catalytic measurement of cytochrome P4501A induction) as a biomarker in fish.
Journal ArticleDOI
Induction of cytochrome P450 as a biomarker for environmental contamination in aquatic ecosystems
Thomas D. Bucheli,Karl Fent +1 more
TL;DR: Application of the induction of cytochrome P4501A (CYP1A), certainly the best studied biomarker, in field trials with freshwater and marine fish is reviewed and shows that CYP1A induction is significantly related to contaminant levels in the environment in 93% of the investigated field studies.
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Hepatic activities of xenobiotic metabolizing enzymes and biliary levels of xenobiotics in English sole (Parophrys vetulus) exposed to environmental contaminants.
Tracy K. Collier,Usha Varanasi +1 more
TL;DR: Exposure studies showed that xenobiotic metabolism, as reflected in hepatic activities of XMEs and levels of FACs in the bile, is altered by exposure to environmental contaminants.
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Effects of Black Rock Harbor sediments on indices of biotransformation, oxidative stress, and DNA integrity in channel catfish
TL;DR: In this paper, a channel catfish (Ictalurus punctatus) was exposed in the laboratory to sediments obtained from either of two sites in Long Island Sound, CT.
References
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Journal ArticleDOI
Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.
TL;DR: The purification of homogeneous glutathione S-transferases B and C from rat liver is described, and only transferases A and C are immunologically related.
Journal ArticleDOI
Determination of protein: A modification of the lowry method that gives a linear photometric response
TL;DR: Under the new conditions there is direct proportionality between absorbance at 650 nm and weight of protein within the range 15–110 μg.
Journal ArticleDOI
Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450.
M.D. Burke,Stephanie Thompson,Clifford R. Elcombe,James R. Halpert,T Haaparanta,Richard T. Mayer +5 more
TL;DR: It is suggested that the use of some or all of these homologous phenoxazone ethers will provide both a simple routine test for the characterization of several types of inducing agents and a powerful tool for investigating the biochemical basis for cyt.
BookDOI
Cytochrome P-450
TL;DR: In this article, high-resolution NMR and 180rlabeling studies indicate that the product is completely the exo isomer and one atom from molecular oxygen is inserted to form the epoxide.
Related Papers (5)
The cytochrome P-450 system in fish, aquatic toxicology and environmental monitoring
Anders Goksøyr,Lars Förlin +1 more