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Open AccessJournal ArticleDOI

Effects of Early Placement of Transjugular Portosystemic Shunts in Patients With High-Risk Acute Variceal Bleeding: a Meta-analysis of Individual Patient Data.

Oana Nicoară-Farcău, +140 more
- 01 Jan 2021 - 
- Vol. 160, Iss: 1
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TLDR
A meta-analysis of data from 1327 patients with cirrhosis, acute variceal bleeding, and Child-Pugh score between 10-13 points or CP-B+AB found that preemptive TIPS increased the proportion who survived for 1 year, in both subgroups separately, compared with drugs plus endoscopy.
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This article is published in Gastroenterology.The article was published on 2021-01-01 and is currently open access. It has received 73 citations till now. The article focuses on the topics: Transjugular intrahepatic portosystemic shunt & Model for End-Stage Liver Disease.

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Citations
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EASL Clinical Practice Guidelines on the management of hepatic encephalopathy.

TL;DR: The EASL Clinical Practice Guidelines (CPGs) on the management of hepatic encephalopathy (HE) as mentioned in this paper present evidence-based answers to a set of relevant questions (where possible, formulated in PICO [patient/population, intervention, comparison and outcomes] format).
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Hepatic encephalopathy

TL;DR: Hepatic encephalopathy (HE) is a prognostically relevant neuropsychiatric syndrome that occurs in the course of acute or chronic liver disease as discussed by the authors , which is the most serious complication of decompensated liver cirrhosis.
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Hepatic encephalopathy.

TL;DR: Hepatic encephalopathy (HE) is a prognostically relevant neuropsychiatric syndrome that occurs in the course of acute or chronic liver disease as mentioned in this paper , which is the most serious complication of decompensated liver cirrhosis.
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Portal hypertension and hepatocellular carcinoma: Des liaisons dangereuses…

TL;DR: In this paper, the consequences of angiogenesis and inflammation in the pathogenesis of portal hypertension and hepatocellular carcinoma (HCC) coexist in the same patients, but also the difficulty to propose adapted treatment when PHT and HCC coexist.
References
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Journal ArticleDOI

The central role of the propensity score in observational studies for causal effects

Paul R. Rosenbaum, +1 more
- 01 Apr 1983 - 
TL;DR: The authors discusses the central role of propensity scores and balancing scores in the analysis of observational studies and shows that adjustment for the scalar propensity score is sufficient to remove bias due to all observed covariates.
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An Introduction to Propensity Score Methods for Reducing the Effects of Confounding in Observational Studies

TL;DR: The propensity score is a balancing score: conditional on the propensity score, the distribution of observed baseline covariates will be similar between treated and untreated subjects, and different causal average treatment effects and their relationship with propensity score analyses are described.
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Propensity score methods for bias reduction in the comparison of a treatment to a non‐randomized control group

TL;DR: The propensity score, defined as the conditional probability of being treated given the covariates, can be used to balance the variance of covariates in the two groups, and therefore reduce bias as mentioned in this paper.
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Expanding consensus in portal hypertension Report of the Baveno VI Consensus Workshop: Stratifying risk and individualizing care for portal hypertension

TL;DR: The aims of these meetings were to develop definitions of key events in portal hypertension and variceal bleeding, to review the existing evidence on the natural history, the diagnosis and the therapeutic modalities of portal hypertension, and to issue evidence-based recommendations for the conduct of clinical trials and the management of patients.
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Portal hypertensive bleeding in cirrhosis: Risk stratification, diagnosis, and management: 2016 practice guidance by the American Association for the study of liver diseases.

TL;DR: This guidance provides a data-supported approach to risk stratification, diagnosis, and management of patients with cirrhosis and portal hypertension (PH), varices, and variceal hemorrhage (VH), and statements are based on the following.
Related Papers (5)

Preemptive-TIPS Improves Outcome in High-Risk Variceal Bleeding: An Observational Study