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Journal ArticleDOI

Electron tomography and holography in materials science

TLDR
An overview of the techniques of electron tomography and electron holography is presented and their capabilities with the aid of case studies that span materials science and the interface between the physical sciences and the life sciences are demonstrated.
Abstract
The rapid development of electron tomography, in particular the introduction of novel tomographic imaging modes, has led to the visualization and analysis of three-dimensional structural and chemical information from materials at the nanometre level. In addition, the phase information revealed in electron holograms allows electrostatic and magnetic potentials to be mapped quantitatively with high spatial resolution and, when combined with tomography, in three dimensions. Here we present an overview of the techniques of electron tomography and electron holography and demonstrate their capabilities with the aid of case studies that span materials science and the interface between the physical sciences and the life sciences.

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Citations
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Journal ArticleDOI

Modulated Magnetic Nanowires for Controlling Domain Wall Motion: Toward 3D Magnetic Memories

TL;DR: Modulated nanowires consisting of alternating nickel and cobalt sections facilitate efficient domain wall pinning at the interfaces of those sections by combining electron holography with micromagnetic simulations.
Journal ArticleDOI

PEBBLES and PEBBLEJUGGLER: software for accurate, unbiased, and fast measurement and analysis of nanoparticle morphology from transmission electron microscopy (TEM) micrographs

TL;DR: Since Pebbles is based on a local modeling procedure, it successfully treats cases such as low contrast NPs, NPs with significant diffraction scattering, and inhomogeneous background which often make conventional thresholding procedures fail.
Journal ArticleDOI

Hybrid nanoscale inorganic cages

TL;DR: A previously unknown edge growth mechanism has led to a new type of cage-structured hybrid metal-semiconductor nanoparticle; a ruthenium cage was grown selectively on the edges of a faceted copper(I) sulphide nanocrystal, contrary to the more commonly observed facet and island growth modes of other hybrids.
Journal ArticleDOI

Monitoring Galvanic Replacement Through Three-Dimensional Morphological and Chemical Mapping

TL;DR: It is demonstrated here that a combination of state-of-the-art EDX mapping with electron tomography results in the unambiguous determination of both morphology transformation and elemental composition of nanostructures in 3D, during galvanic replacement of Ag nanocubes.
Journal ArticleDOI

3D morphometry of red blood cells by digital holography.

TL;DR: This work proves the new procedure for healthy red blood cells (RBCs) (i.e., discocytes) having a concave surface in their central region and shows that the method can be also useful to classify, in terms of morphology, different varieties of RBCs.
References
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Journal ArticleDOI

Representation of a Function by Its Line Integrals, with Some Radiological Applications

TL;DR: In this paper, a method for finding a real function in a finite region of a plane given its line integrals along all straight lines intersecting the region was given, and the solution found is applicable to three problems of interest for precise radiology and radiotherapy: (1) the determination of a variable x-ray absorption coefficient in two dimensions, (2) the distribution of positron annihilations when there is an inhomogeneous distribution of the positron emitter in matter, and (3) a variable density of matter with constant chemical composition, using the energy loss
Journal ArticleDOI

Iterative methods for the three-dimensional reconstruction of an object from projections

TL;DR: It is shown that in general ART produces erroneous reconstructions, and an alternative iterative method is proposed which will give correct reconstructions under certain conditions.
Journal ArticleDOI

Reconstruction of Three Dimensional Structures from Electron Micrographs

TL;DR: General principles are formulated for the objective reconstruction of a three dimensional object from a set of electron microscope images and applied to the calculation of aThree dimensional density map of the tail of bacteriophage T4.
MonographDOI

Three-Dimensional Electron Microscopy of Macromolecular Assemblies

Joachim Frank
TL;DR: In this article, a three-dimensional reconstruction interpretation of 3D images of macromolecules is presented. Butts et al. reconstructed macromoles from micrographs of single macromolcules.
Journal ArticleDOI

Molecular structure determination by electron microscopy of unstained crystalline specimens.

TL;DR: The projected structures of two unstained periodic biological specimens, the purple membrane and catalase, have been determined by electron microscopy to resolutions of 7 A and 9 A, respectively.
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