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Journal ArticleDOI

Electron tomography and holography in materials science

TLDR
An overview of the techniques of electron tomography and electron holography is presented and their capabilities with the aid of case studies that span materials science and the interface between the physical sciences and the life sciences are demonstrated.
Abstract
The rapid development of electron tomography, in particular the introduction of novel tomographic imaging modes, has led to the visualization and analysis of three-dimensional structural and chemical information from materials at the nanometre level. In addition, the phase information revealed in electron holograms allows electrostatic and magnetic potentials to be mapped quantitatively with high spatial resolution and, when combined with tomography, in three dimensions. Here we present an overview of the techniques of electron tomography and electron holography and demonstrate their capabilities with the aid of case studies that span materials science and the interface between the physical sciences and the life sciences.

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Journal ArticleDOI

Metal oxide nanowire chemical and biochemical sensors

TL;DR: The fabrication methods and the basic properties of the metal-oxide nanostructures referred as nanowires are presented and reviewed in this article, with particular emphasis to the electrical and optical properties and their useful implementation for chemical and biochemical sensing.
Journal ArticleDOI

Three-Dimensional Composition and Electric Potential Mapping of III-V Core-Multishell Nanowires by Correlative STEM and Holographic Tomography.

TL;DR: In this paper, the functional potentials of a single GaAs-AlGaAs core-multishell nanowire were derived by combining EHT and high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) tomography.
Reference EntryDOI

Pair Distribution Functions Analysis

TL;DR: The foundations and practical aspects of atomic pair distribution functions analysis as a tool for characterizing the structure of materials of limited structural coherence are described in brief as discussed by the authors, where the authors propose a pair distribution function analysis approach for X-ray diffraction.
Journal ArticleDOI

High-resolution three-dimensional probes of biomaterials and their interfaces

TL;DR: The fundamentals of ET are reviewed and its recent applications in probing the three-dimensional structure of bioceramics and their interfaces are highlighted, with particular focus on the hydroxyapatite–bone interface, titanium dioxide-bone interface and a mesoporous titania coating for controlled drug release.
Journal ArticleDOI

3D Characterization of Human Nano-osseointegration by On-Axis Electron Tomography without the Missing Wedge.

TL;DR: This work demonstrates a near artifact-free 3D visualization of the nanotopographies of the implant surface oxide layer and bone growth into these features that serves as direct evidence of nano-osseointegration and as a potential platform to evaluate differently structured implant surfaces.
References
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Journal ArticleDOI

Representation of a Function by Its Line Integrals, with Some Radiological Applications

TL;DR: In this paper, a method for finding a real function in a finite region of a plane given its line integrals along all straight lines intersecting the region was given, and the solution found is applicable to three problems of interest for precise radiology and radiotherapy: (1) the determination of a variable x-ray absorption coefficient in two dimensions, (2) the distribution of positron annihilations when there is an inhomogeneous distribution of the positron emitter in matter, and (3) a variable density of matter with constant chemical composition, using the energy loss
Journal ArticleDOI

Iterative methods for the three-dimensional reconstruction of an object from projections

TL;DR: It is shown that in general ART produces erroneous reconstructions, and an alternative iterative method is proposed which will give correct reconstructions under certain conditions.
Journal ArticleDOI

Reconstruction of Three Dimensional Structures from Electron Micrographs

TL;DR: General principles are formulated for the objective reconstruction of a three dimensional object from a set of electron microscope images and applied to the calculation of aThree dimensional density map of the tail of bacteriophage T4.
MonographDOI

Three-Dimensional Electron Microscopy of Macromolecular Assemblies

Joachim Frank
TL;DR: In this article, a three-dimensional reconstruction interpretation of 3D images of macromolecules is presented. Butts et al. reconstructed macromoles from micrographs of single macromolcules.
Journal ArticleDOI

Molecular structure determination by electron microscopy of unstained crystalline specimens.

TL;DR: The projected structures of two unstained periodic biological specimens, the purple membrane and catalase, have been determined by electron microscopy to resolutions of 7 A and 9 A, respectively.
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