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Enzyme catalysis in organic synthesis : a comprehensive handbook
Karlheinz Drauz,Herbert Waldmann +1 more
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TLDR
A tabular survey of commercially available enzymes can be found in this paper, with a focus on enzymes that are used in organic synthesis, such as: production and isolation of enzymes, immobilization of enzymes reaction techniques, use of growing or resting cells, applications of enqumes in organically synthesized organic synthesis hydrolysis and formation of C-O bonds, C-N bonds, P-O bond formation, reduction reactions oxidation reactions isomerizations introduction and removal of protecting groups extremophiles catalytic antibodies enqumatic analysis and biosensors prtoein engineeringAbstract:
Production and isolation of enzymes immobilization of enzymes reaction techniques use of growing or resting cells applications of enqumes in organic synthesis hydrolysis and formation of C-O bonds, C-N bonds, P-O bonds formation of C-C bonds reduction reactions oxidation reactions isomerizations introduction and removal of protecting groups extremophiles catalytic antibodies enqumatic analysis and biosensors prtoein engineering tabular survey of commercially available enzymes.read more
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Enantioselective synthesis of 2-hydroxy-1-indanone, a key precursor of enantiomerically pure 1-amino-2-indanol
TL;DR: Enantiomerically pure (R )- or (S )-2-hydroxy-1-indanone was synthesized by enzymatic kinetic resolution of racemic 2-acetoxy-1,indanones through hydrolysis or transesterification as discussed by the authors.
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Enantioselective resolution of racemic compounds by cell surface displayed lipase
TL;DR: Results suggest that cell surface displayed lipase has a high enantioselectivity, broad substrate specificity and reusability, which makes it an excellent system for the production of various optically active compounds.
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Tools for Selective Enzyme Reaction Steps in the Synthesis of Laboratory Chemicals
TL;DR: The introduction of selective enzyme reactions into an entire synthetic process has resulted in harmonization of improvements in economic efficiency with resultant solutions to health, safety and environment problems and the potential to shorten development time.
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Kinetic resolution of 1-phenylethanol integrated with separation of substrates and products by a supported ionic liquid membrane
Francisco J. Hernández-Fernández,A.P. de los Ríos,F. Tomás-Alonso,Demetrio Gómez,Gloria Víllora +4 more
TL;DR: In this paper, the kinetic resolution of rac-1-phenylethanol by transesterification with several vinyl esters catalysed by a commercial immobilized Candida antarctica lipase B (Novozym 435) was carried out in n-hexane at different water contents.
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Biocatalytic asymmetric reduction of 3-acetylisoxazoles
TL;DR: The reduction of the carbonyl group in 3-acetylisoxazole derivatives by algae and plant cells gave the corresponding (S)-alcohols with high enantioselectivities.