scispace - formally typeset
Journal ArticleDOI

Gold nanoparticle-enabled biological and chemical detection and analysis

TLDR
An overview of the optical properties of AuNPs is presented, followed by a more detailed literature survey, and some technical issues that remain to be solved in order to move the technique forward.
Abstract
Gold nanoparticles (AuNPs) are some of the most extensively studied nanomaterials. Because of their unique optical, chemical, electrical, and catalytic properties, AuNPs have attracted enormous amount of interest for applications in biological and chemical detection and analysis. The purpose of this critical review is to provide the readers with an update on the recent developments in the field of AuNPs for sensing applications based on their optical properties. An overview of the optical properties of AuNPs is presented first, followed by a more detailed literature survey. As the last part of this review, we compare the advantages and disadvantages of each technique, briefly discuss their commercialization status, and some technical issues that remain to be solved in order to move the technique forward (151 references).

read more

Citations
More filters
Journal ArticleDOI

Supramolecular self-assemblies as functional nanomaterials

TL;DR: This compilation illustrates how, based on the rules of supramolecular chemistry, the bottom-up approach to design functional objects at the nanoscale is currently producing highly sophisticated materials oriented towards a growing number of applications with high societal impact.
Journal ArticleDOI

Nanoparticle-Based Immunochemical Biosensors and Assays: Recent Advances and Challenges

TL;DR: This work reviews the progress achieved during the recent five years in immunochemical biosensors (immunosensors) combined with nanoparticles for enhanced sensitivity and introduces antibodies as classic recognition elements.
Journal ArticleDOI

DNA Switches: From Principles to Applications

TL;DR: This Review addresses the implementation of the information encoded in nucleic acids to develop DNA switches to tailor switchable DNA hydrogels, for the controlled drug-release and for the activation of switchable enzyme cascades.
Journal ArticleDOI

Fluorescent, MRI, and colorimetric chemical sensors for the first-row d-block metal ions

TL;DR: Review of chemical sensors developed for the detection of the first-row d-block metals (except Cu and Zn): Cr, Mn, Fe, Co, and Ni focuses on the development of fluorescent sensors, colorimetric sensors, and responsive MRI contrast agents for these transition metals.
Journal ArticleDOI

Strategies for enhancing the sensitivity of plasmonic nanosensors

TL;DR: In this article, a review highlights recent progress on different strategies used for improving the sensitivity of plasmonic nanosensors, classified into three categories based on their different sensing mechanisms: (1) sensing based on target-induced local refractive index changes, (2) colorimetric sensing, and (3) amplification of detection sensitivity based on nanoparticle growth.
References
More filters
Journal ArticleDOI

A DNA-based Method for Rationally Assembling Nanoparticles Into Macroscopic Materials

TL;DR: A method for assembling colloidal gold nanoparticles rationally and reversibly into macroscopic aggregates by using the specificity of DNA interactions to direct the interactions between particles of different size and composition is described.
Journal ArticleDOI

Localized Surface Plasmon Resonance Spectroscopy and Sensing

TL;DR: This review describes recent fundamental spectroscopic studies that reveal key relationships governing the LSPR spectral location and its sensitivity to the local environment, including nanoparticle shape and size and introduces a new form of L SPR spectroscopy, involving the coupling between nanoparticle plasmon resonances and adsorbate molecular resonances.
Journal ArticleDOI

Surface-enhanced spectroscopy

TL;DR: The surface-enhanced Raman scattering (SERS) effect was first discovered by Fleischmann, Van Duyne, Creighton, and Creighton as discussed by the authors, who showed that molecules adsorbed on specially prepared silver surfaces produce a Raman spectrum that is at times a millionfold more intense than expected.
Journal ArticleDOI

Calculated Absorption and Scattering Properties of Gold Nanoparticles of Different Size, Shape, and Composition: Applications in Biological Imaging and Biomedicine

TL;DR: While nanorods with a higher aspect ratio along with a smaller effective radius are the best photoabsorbing nanoparticles, the highest scattering contrast for imaging applications is obtained from nanorod of high aspect ratio with a larger effective radius.
Related Papers (5)