Health benefits, costs, and cost-effectiveness of earlier eligibility for adult antiretroviral therapy and expanded treatment coverage: A combined analysis of 12 mathematical models
Jeffrey W. Eaton,Nicolas A Menzies,John Stover,Valentina Cambiano,Leonid Chindelevitch,Anne Cori,Jan A. C. Hontelez,Jan A. C. Hontelez,Jan A. C. Hontelez,Salal Humair,Cliff C. Kerr,Daniel J. Klein,Sharmistha Mishra,Sharmistha Mishra,Kate M. Mitchell,Brooke E Nichols,Peter Vickerman,Roel Bakker,Till Bärnighausen,Till Bärnighausen,Anna Bershteyn,David E. Bloom,Marie-Claude Boily,Stewart T. Chang,Ted Cohen,Ted Cohen,Peter J. Dodd,Christophe Fraser,Chaitra Gopalappa,Jens D Lundgren,Jens D Lundgren,Natasha K. Martin,Natasha K. Martin,Evelinn Mikkelsen,Elisa Mountain,Quang D. Pham,Michael Pickles,Andrew N. Phillips,Lucy Platt,Carel Pretorius,H Prudden,Joshua A. Salomon,David A. M. C. van de Vijver,Sake J. de Vlas,Bradley G. Wagner,Richard G. White,David Wilson,Lei Zhang,John M. Blandford,Gesine Meyer-Rath,Gesine Meyer-Rath,Michelle Remme,Paul Revill,Nalinee Sangrujee,Fern Terris-Prestholt,Meg Doherty,Nathan Shaffer,Philippa Easterbrook,Gottfried Hirnschall,Timothy B. Hallett +59 more
Reads0
Chats0
TLDR
Estimates suggest that earlier eligibility for antiretroviral therapy is very cost effective in low-income and middle-income settings, although these estimates should be revisited when more data become available.About:
This article is published in The Lancet Global Health.The article was published on 2014-01-01 and is currently open access. It has received 217 citations till now. The article focuses on the topics: Eligibility Determination & Cost effectiveness.read more
Citations
More filters
Journal ArticleDOI
Initiation of antiretroviral therapy in early asymptomatic HIV infection
Sean Emery,Shweta Sharma,Gerd Fätkenheuer,Josep M. Llibre,Jean-Michel Moli,Paula Munderi,Robin Wood,Karin L. Klingman,Simon Collins,H. Clifford Lane,Andrew N. Phil,James D. Neaton +11 more
TL;DR: The initiation of antiretroviral therapy in HIV-positive adults with a CD4+ count of more than 500 cells per cubic millimeter provided net benefits over starting such therapy in patients after the CD4+, but the risks of unscheduled hospital admissions were similar in the two groups.
Journal ArticleDOI
Effects of Response to 2014-2015 Ebola Outbreak on Deaths from Malaria, HIV/AIDS, and Tuberculosis, West Africa.
TL;DR: Reduced access to healthcare during the Epstein-Barr virus outbreak substantially increased mortality rates from other diseases.
Journal ArticleDOI
Defeating AIDS—advancing global health
Peter Piot,Salim S. Abdool Karim,Robert Hecht,Helena Legido-Quigley,Helena Legido-Quigley,Kent Buse,John Stover,Stephen C Resch,Theresa Ryckman,Sigrun Møgedal,Mark Dybul,Eric Goosby,Charlotte Watts,Nduku Kilonzo,Joanne McManus,Michel Sidibé +15 more
TL;DR: The path to ending AIDS as a public health threat by 2030 as set out in this report should be a major part of the post-2015 development agenda.
References
More filters
Journal ArticleDOI
Prevention of HIV-1 Infection with Early Antiretroviral Therapy
Myron S. Cohen,Ying Q. Chen,Marybeth McCauley,Theresa Gamble,Mina C. Hosseinipour,Nagalingeswaran Kumarasamy,James Hakim,Johnstone Kumwenda,Beatriz Grinsztejn,José Henrique Pilotto,Sheela Godbole,Sanjay Mehendale,Suwat Chariyalertsak,Breno Santos,Kenneth H. Mayer,Irving F. Hoffman,Susan H. Eshleman,Estelle Piwowar-Manning,Lei Wang,Joseph Makhema,Lisa A. Mills,Guy de Bruyn,Ian Sanne,Joseph J. Eron,Joel E. Gallant,Diane V. Havlir,Susan Swindells,Heather J. Ribaudo,Vanessa Elharrar,David N. Burns,Taha E. Taha,Karin Nielsen-Saines,David D. Celentano,Myron Essex,Thomas R. Fleming +34 more
TL;DR: In this article, Antiretroviral therapy that reduces viral replication could limit the transmission of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples.
Journal ArticleDOI
Prevention of HIV-1 infection with early antiretroviral therapy
TL;DR: The exciting evidence generated by this paper – that antiretroviral treatment of HIV-1 infection definitively reduces the risk of onward transmission of the virus by 96% – was rightly dubbed Science magazine's ‘Breakthrough of the Year’ in 2011.
Related Papers (5)
Prevention of HIV-1 Infection with Early Antiretroviral Therapy
Myron S. Cohen,Ying Q. Chen,Marybeth McCauley,Theresa Gamble,Mina C. Hosseinipour,Nagalingeswaran Kumarasamy,James Hakim,Johnstone Kumwenda,Beatriz Grinsztejn,José Henrique Pilotto,Sheela Godbole,Sanjay Mehendale,Suwat Chariyalertsak,Breno Santos,Kenneth H. Mayer,Irving F. Hoffman,Susan H. Eshleman,Estelle Piwowar-Manning,Lei Wang,Joseph Makhema,Lisa A. Mills,Guy de Bruyn,Ian Sanne,Joseph J. Eron,Joel E. Gallant,Diane V. Havlir,Susan Swindells,Heather J. Ribaudo,Vanessa Elharrar,David N. Burns,Taha E. Taha,Karin Nielsen-Saines,David D. Celentano,Myron Essex,Thomas R. Fleming +34 more