Higher BMI, but not obesity-related genetic polymorphisms, correlates with lower structural connectivity of the reward network in a population-based study
Frauke Beyer,Frauke Beyer,Rui Zhang,Markus Scholz,Kerstin Wirkner,Markus Loeffler,Michael Stumvoll,Arno Villringer,Arno Villringer,A. Veronica Witte,A. Veronica Witte +10 more
TLDR
Evidence is provided that higher BMI correlates with lower reward network structural connectivity, in line with previous findings of obesity-related decline in white matter microstructure.Citations
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OUP accepted manuscript
TL;DR: Engel et al. as discussed by the authors presented a study on the life-adult-study at the Leipzig Institute for Medical Informatics, Statistics and Epidemiology (Engel-Engel Institute) in Germany.
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Role of the striatal dopamine, GABA and opioid systems in mediating feeding and fat intake
TL;DR: In this article , the authors provided insights concerning the impact of feeding, including fat intake, on different types of receptors and neurotransmitters present in the striatal complex and in particular the nucleus accumbens, with a focus on dopamine, GABA and the opioid system.
Obesity gene NEGR1 associated with white matter integrity in healthy young adults
Emily L. Dennis,Neda Jahanshad,Meredith N. Braskie,Nicholus M. Warstadt,Derrek P. Hibar,Omid Kohannim,Talia M. Nir,Katie L. McMahon,G. I. de Zubicaray,Grant W. Montgomery,Nicholas G. Martin,Arthur W. Toga,Margaret J. Wright,Paul M. Thompson +13 more
TL;DR: This is the first study to find an association between an obesity risk gene and differences in white matter integrity, and suggests that NEGR1 has effects on brain structure independent of its effect on obesity.
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Brain functional and structural magnetic resonance imaging of obesity and weight loss interventions
Guanya Li,Yang Hu,Wenchao Zhang,Jia Wang,Weibin Ji,Peter Manza,Nora D. Volkow,Yi Zhang,Gene-Jack Wang +8 more
TL;DR: A comprehensive literature review of the recent neuroimaging advances on the underlying neural mechanisms of both obesity and interventions, in the hope of guiding development of novel and effective treatments is provided in this article .
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Exploring the genetic correlation between obesity-related traits and regional brain volumes: Evidence from UK Biobank cohort
Liying Wang,Michael K. Stickland +1 more
TL;DR: Based on a mixed linear model (MLM), the authors analyzed the association between 1,498 obesity-related SNPs in the GWAS catalog and 164 regional brain volumes from 29,420 participants in UK Biobank.
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