Journal ArticleDOI
How do you feel? Interoception: the sense of the physiological condition of the body.
TLDR
Functional anatomical work has detailed an afferent neural system in primates and in humans that represents all aspects of the physiological condition of the physical body that might provide a foundation for subjective feelings, emotion and self-awareness.Abstract:
As humans, we perceive feelings from our bodies that relate our state of well-being, our energy and stress levels, our mood and disposition. How do we have these feelings? What neural processes do they represent? Recent functional anatomical work has detailed an afferent neural system in primates and in humans that represents all aspects of the physiological condition of the physical body. This system constitutes a representation of 'the material me', and might provide a foundation for subjective feelings, emotion and self-awareness.read more
Citations
More filters
Journal ArticleDOI
Neural Origins of Human Sickness in Interoceptive Responses to Inflammation
Neil A. Harrison,Neil A. Harrison,Lena Brydon,Cicely Walker,Marcus A. Gray,Andrew Steptoe,Raymond J. Dolan,Hugo D. Critchley +7 more
TL;DR: These findings suggest that peripheral infection selectively influences central nervous system function to generate core symptoms of sickness and reorient basic motivational states.
Journal ArticleDOI
An fMRI study of affective perspective taking in individuals with psychopathy: imagining another in pain does not evoke empathy.
TL;DR: Patterns of brain activation and effective connectivity associated with differential perspective-taking provide a better understanding of empathy dysfunction in psychopathy, and have the potential to inform intervention programs for this complex clinical problem.
Journal ArticleDOI
Inactivation of the Interoceptive Insula Disrupts Drug Craving and Malaise Induced by Lithium
TL;DR: It is concluded that the insular cortex is a key structure in the perception of bodily needs that provides direction to motivated behaviors in drug craving and in the behavioral signs of malaise.
Journal ArticleDOI
Resting-state functional connectivity in treatment-resistant depression.
Su Lui,Qizhu Wu,Lihua Qiu,Xun Yang,Weihong Kuang,Raymond C.K. Chan,Xiaoqi Huang,Graham J. Kemp,Andrea Mechelli,Qiyong Gong +9 more
TL;DR: The results suggest that nonrefractory and refractory depression are characterized by distinct functional deficits in distributed brain networks.
Journal ArticleDOI
Symptoms and the body: Taking the inferential leap
TL;DR: The prevailing theoretical approach to this problem is described and a new and more comprehensive model of the body‐symptom relationship that integrates existing concepts within a unifying framework that addresses many of the shortcomings of current theory is proposed.
References
More filters
Book
The Principles of Psychology
TL;DR: For instance, the authors discusses the multiplicity of the consciousness of self in the form of the stream of thought and the perception of space in the human brain, which is the basis for our work.
Book
Descartes' Error: Emotion, Reason, and the Human Brain
TL;DR: The authors argued that rational decisions are not the product of logic alone - they require the support of emotion and feeling, drawing on his experience with neurological patients affected with brain damage, Dr Damasio showed how absence of emotions and feelings can break down rationality.
Book
The Integrative Action of the Nervous System
TL;DR: In this article, the Integrative Action of the Nervous System [1906] Charles S. Sherrington, W.B. Hadden, and W.A. Baly have been discussed.