Journal ArticleDOI
How do you feel? Interoception: the sense of the physiological condition of the body.
TLDR
Functional anatomical work has detailed an afferent neural system in primates and in humans that represents all aspects of the physiological condition of the physical body that might provide a foundation for subjective feelings, emotion and self-awareness.Abstract:
As humans, we perceive feelings from our bodies that relate our state of well-being, our energy and stress levels, our mood and disposition. How do we have these feelings? What neural processes do they represent? Recent functional anatomical work has detailed an afferent neural system in primates and in humans that represents all aspects of the physiological condition of the physical body. This system constitutes a representation of 'the material me', and might provide a foundation for subjective feelings, emotion and self-awareness.read more
Citations
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Journal ArticleDOI
Role of Prelimbic GABAergic Circuits in Sensory and Emotional Aspects of Neuropathic Pain
Zizhen Zhang,Zizhen Zhang,Vinicius M. Gadotti,Vinicius M. Gadotti,Lina Chen,Lina Chen,Ivana A. Souza,Ivana A. Souza,Patrick L. Stemkowski,Patrick L. Stemkowski,Gerald W. Zamponi,Gerald W. Zamponi +11 more
TL;DR: It is found that peripheral nerve injury inhibits pyramidal cell firing in the prelimbic area of the prefrontal cortex as a result of feed-forward inhibition mediated by parvalbumin-expressing GABAergic interneurons, and this region is identified as a potential target for pain therapeutics.
Journal ArticleDOI
ThermoTRP channels and cold sensing: what are they really up to?
TL;DR: This review examines the roles of a cold- and menthol-activated ion channel, transient receptor potential (melastatin)-8, and another TRP channel, TRP (ankyrin-like)-1, which has been suggested to underlie cold nociception.
Journal ArticleDOI
Dwelling quietly in the rich club: brain network determinants of slow cortical fluctuations
Leonardo L. Gollo,Andrew Zalesky,R. Matthew Hutchison,Martijn P. van den Heuvel,Michael Breakspear,Michael Breakspear +5 more
TL;DR: This article explored the origin of slowly fluctuating patterns of synchronization within the topological core of brain regions known as the rich club, implicated in the regulation of mood and introspection, and found that a constellation of densely interconnected regions played a central role in promoting a stable, dynamical core of spontaneous activity in the primate cortex.
Journal ArticleDOI
Fear and the amygdala: manipulation of awareness generates differential cerebral responses to phobic and fear-relevant (but nonfeared) stimuli.
Katrina Carlsson,Karl Magnus Petersson,Daniel Lundqvist,Andreas Karlsson,Martin Ingvar,Arne Öhman +5 more
TL;DR: A shift from top-down control to an affectively driven system optimized for speed was observed in phobic relative to fear-relevant aware processing.
Journal ArticleDOI
The invisible hand illusion: Multisensory integration leads to the embodiment of a discrete volume of empty space
TL;DR: These findings demonstrate that the integration of temporally and spatially congruent multisensory signals in a premotor-intraparietal circuit is sufficient to redefine the spatial boundaries of the bodily self, even when visual information directly contradicts the presence of a physical limb at the location of the perceived illusory hand.
References
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Book
The Principles of Psychology
TL;DR: For instance, the authors discusses the multiplicity of the consciousness of self in the form of the stream of thought and the perception of space in the human brain, which is the basis for our work.
Book
Descartes' Error: Emotion, Reason, and the Human Brain
TL;DR: The authors argued that rational decisions are not the product of logic alone - they require the support of emotion and feeling, drawing on his experience with neurological patients affected with brain damage, Dr Damasio showed how absence of emotions and feelings can break down rationality.
Book
The Integrative Action of the Nervous System
TL;DR: In this article, the Integrative Action of the Nervous System [1906] Charles S. Sherrington, W.B. Hadden, and W.A. Baly have been discussed.