Journal ArticleDOI
How do you feel? Interoception: the sense of the physiological condition of the body.
TLDR
Functional anatomical work has detailed an afferent neural system in primates and in humans that represents all aspects of the physiological condition of the physical body that might provide a foundation for subjective feelings, emotion and self-awareness.Abstract:
As humans, we perceive feelings from our bodies that relate our state of well-being, our energy and stress levels, our mood and disposition. How do we have these feelings? What neural processes do they represent? Recent functional anatomical work has detailed an afferent neural system in primates and in humans that represents all aspects of the physiological condition of the physical body. This system constitutes a representation of 'the material me', and might provide a foundation for subjective feelings, emotion and self-awareness.read more
Citations
More filters
Journal ArticleDOI
Processing of nociceptive input from posterior to anterior insula in humans.
TL;DR: This study shows that both posterior and anterior subdivisions of the insular cortex respond to a nociceptive heat stimulus within a 200–400 ms latency range, and suggests that nocICEptive input is first processed in the posterior insula and then conveyed to the anterior insula, where the emotional reaction to pain is elaborated.
Journal ArticleDOI
Appetite changes reveal depression subgroups with distinct endocrine, metabolic, and immune states
W. Kyle Simmons,W. Kyle Simmons,W. Kyle Simmons,Kaiping Burrows,Jason A. Avery,Kara L. Kerr,Ashlee Taylor,Jerzy Bodurka,William T. Potter,T. Kent Teague,T. Kent Teague,Wayne C. Drevets +11 more
TL;DR: Novel evidence is provided linking aberrations in homeostatic signaling pathways within depression subtypes to the activity of neural systems that respond to food cues and select when, what, and how much to eat is provided.
Journal ArticleDOI
Distinctive Neurons of the Anterior Cingulate and Frontoinsular Cortex: A Historical Perspective
William W. Seeley,Florian T. Merkle,Stephanie E. Gaus,A.D. (Bud) Craig,John M. Allman,Patrick R. Hof +5 more
TL;DR: The historical accounts of these neurons are reviewed and a German-to-English translation of von Economo's seminal paper describing the neurons which have come to bear his name is provided.
Journal ArticleDOI
Neural circuitry of PTSD with or without mild traumatic brain injury: a meta-analysis.
TL;DR: It is suggested that the middle frontal gyrus may be an appropriate area for future investigations aimed at disentangling PTSD and mTBI.
Journal ArticleDOI
A putative role for cytokines in the impaired appetite in depression
TL;DR: It is suggested that cytokines are differentially altered in these subtypes of depression, and that this may explain some of the inconsistency in the reported findings of cytokine as well as leptin levels in depressed patients.
References
More filters
Book
The Principles of Psychology
TL;DR: For instance, the authors discusses the multiplicity of the consciousness of self in the form of the stream of thought and the perception of space in the human brain, which is the basis for our work.
Book
Descartes' Error: Emotion, Reason, and the Human Brain
TL;DR: The authors argued that rational decisions are not the product of logic alone - they require the support of emotion and feeling, drawing on his experience with neurological patients affected with brain damage, Dr Damasio showed how absence of emotions and feelings can break down rationality.
Book
The Integrative Action of the Nervous System
TL;DR: In this article, the Integrative Action of the Nervous System [1906] Charles S. Sherrington, W.B. Hadden, and W.A. Baly have been discussed.