Journal ArticleDOI
Hypolipidemic Effect of Green Tea Leaves through Induction of Antioxidant and Phase II Enzymes Including Superoxide Dismutase, Catalase, and Glutathione S-Transferase in Rats
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TLDR
The results suggested that long-term feeding of green tea leaves was not toxic to the liver or kidney and the activities of antioxidant enzymes and phase II enzyme and glutathione concentration in the liver of Wistar rats were significantly higher in the treated group.Abstract:
In this animal study, Wistar rats were fed 2.5% green tea (longjing) leaves, for 27 and 63 weeks; the changes of GOT, GPT, γ-GT, and creatinine were not significant in the treated group as compared with the control. These results suggested that long-term feeding of green tea leaves was not toxic to the liver or kidney. Serum total cholesterol, triglyceride, and LDL-C were decreased in the tested group. Interestingly, the dietary intakes of the two groups were approximately the same, but the body weights of the tea-fed group were decreased 10−18% compared with those of the control. The activities of antioxidant enzymes (SOD and catalase) and phase II enzyme (GST) and glutathione concentration in the liver of Wistar rats were significantly higher in the treated group. The biological significance of these results can be implicated in relation to the hypolipidemic effect as well as the cancer chemopreventive action of green tea. Keywords: Longjing tea; GST; HDL-C; hypolipidemic; LDL-C; phase II enzyme; SODread more
Citations
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Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.
Jane V. Higdon,Balz Frei +1 more
TL;DR: The effects of tea and green tea catechins on biomarker of oxidative stress, especially oxidative DNA damage, appear very promising in animal models, but data on biomarkers of in vivo oxidative stress in humans are limited.
Journal ArticleDOI
Tea polyphenols for health promotion
Naghma Khan,Hasan Mukhtar +1 more
TL;DR: In vitro and animal studies provide strong evidence that polyphenols derived from tea may possess the bioactivity to affect the pathogenesis of several chronic diseases.
Journal ArticleDOI
Antioxidant Activity of Tea Polyphenols In Vivo: Evidence from Animal Studies
Balz Frei,Jane V. Higdon +1 more
TL;DR: Most promising are the consistent findings in animal models of skin, lung, colon, liver and pancreatic cancer that tea and tea polyphenol administration inhibit carcinogen-induced increases in the oxidized DNA base, 8-hydroxy-2'-deoxyguanosine.
Journal ArticleDOI
A review of latest research findings on the health promotion properties of tea
TL;DR: Experimentation with new accurate tools provide useful information about the metabolism of tea components in the body, their mode of action as antioxidants at the cellular level and their protective role in the development of cancer, cardiovascular disease and other pathologies.
Journal ArticleDOI
Tea, Kombucha, and health: a review.
C. Dufresne,Edward R. Farnworth +1 more
TL;DR: The intensive research about the effects of tea on health provide a good starting point and are summarized to get a better understanding of the complex mechanisms that could be implicated in the physiological activity of both beverages.
References
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TL;DR: The purification of homogeneous glutathione S-transferases B and C from rat liver is described, and only transferases A and C are immunologically related.
Journal ArticleDOI
A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases.
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Journal ArticleDOI
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TL;DR: Overall, the present data suggest that protection against oxidative damage and related disease is best served by the variety of antioxidant substances found in fruit and vegetables.
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