Incidence and Prevalence of Celiac Disease and Dermatitis Herpetiformis in the UK Over Two Decades: Population-Based Study
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TLDR
A fourfold increase in the incidence of CD in the United Kingdom over 22 years is found, with large regional variations in prevalence, which could reflect differences in diagnosis between CD and DH and the possibility that diagnosing and treating CD prevents the development of DH.About:
This article is published in The American Journal of Gastroenterology.The article was published on 2014-05-01 and is currently open access. It has received 222 citations till now. The article focuses on the topics: Incidence (epidemiology).read more
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Human autoimmune diseases: a comprehensive update.
TL;DR: The identification of cytokines and chemokines, and their cognate receptors, has led to novel therapies that block pathological inflammatory responses within the target organ and have greatly improved the therapeutic effect in patients with autoimmune disease, particularly rheumatoid arthritis.
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Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease.
Aaron Lerner,Torsten Matthias +1 more
TL;DR: It is hypothesized that commonly used industrial food additives abrogate human epithelial barrier function, thus, increasing intestinal permeability through the opened tight junction, resulting in entry of foreign immunogenic antigens and activation of the autoimmune cascade.
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Celiac disease and non-celiac gluten sensitivity
TL;DR: Although a gluten-free diet is effective in most patients, this diet can be burdensome and can limit quality of life; consequently, non-dietary therapies are at various stages of development.
Journal ArticleDOI
Incidence of Celiac Disease Is Increasing Over Time : A Systematic Review and Meta-analysis
James King,Jocelyn Jeong,Fox E. Underwood,Joshua Quan,Nicola Panaccione,Joseph W. Windsor,Stephanie Coward,Jennifer deBruyn,Paul E. Ronksley,Abdel Aziz M. Shaheen,Hude Quan,Jenny Godley,Sander Veldhuyzen van Zanten,Benjamin Lebwohl,Siew C. Ng,Jonas F. Ludvigsson,Gilaad G. Kaplan +16 more
TL;DR: Overall, the incidence of celiac disease has been significantly rising in the latter half of the 20th century and into the 21st century throughout the Western world.
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Systematic review with meta-analysis : associations between coeliac disease and type 1 diabetes
TL;DR: In the past decade, a number of population‐based studies have examined the prevalence of coeliac disease in individuals with type 1 diabetes but prevalences have differed considerably.
References
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Journal ArticleDOI
The Oslo definitions for coeliac disease and related terms
Jonas F. Ludvigsson,Daniel A. Leffler,Julio C. Bai,Federico Biagi,Alessio Fasano,Peter H.R. Green,Marios Hadjivassiliou,Katri Kaukinen,Ciaran P. Kelly,Jonathan N. Leonard,Knut E.A. Lundin,Joseph A. Murray,David S Sanders,David S Sanders,Marjorie M. Walker,Fabiana Zingone,Carolina Ciacci +16 more
TL;DR: A multidisciplinary task force of 16 physicians from seven countries used the electronic database PubMed to review the literature for CD-related terms and suggested a definition for each term, followed by feedback through a web survey on definitions and discussions during a meeting in Oslo.
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Validation and validity of diagnoses in the General Practice Research Database: a systematic review
TL;DR: The range of methods used to validate diagnoses in the General Practice Research Database (GPRD) are investigated, to summarize findings and to assess the quality of these validations.
Journal ArticleDOI
Increasing prevalence of coeliac disease over time.
Sini Lohi,K. Mustalahti,Katri Kaukinen,Kaija Laurila,Pekka Collin,H. Rissanen,Olli Lohi,E. Bravi,M. Gasparin,Antti Reunanen,Markku Mäki +10 more
TL;DR: The number of coeliac disease diagnoses has increased in the recent past and according to screening studies, the total prevalence of the disorder is around 1%.
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Jonas F. Ludvigsson,Jonas F. Ludvigsson,Julio C. Bai,Federico Biagi,Timothy R. Card,Carolina Ciacci,Paul J. Ciclitira,Peter H.R. Green,Marios Hadjivassiliou,Anne Holdoway,David A. van Heel,Katri Kaukinen,Daniel A. Leffler,Jonathan N. Leonard,Knut E.A. Lundin,Norma McGough,Mike Davidson,Joseph A. Murray,Gillian L Swift,Marjorie M. Walker,Fabiana Zingone,David S Sanders +21 more