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Infectious Diseases of Humans: Dynamics and Control
Roy M. Anderson,Robert M. May +1 more
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TLDR
This book discusses the biology of host-microparasite associations, dynamics of acquired immunity heterogeneity within the human community indirectly transmitted helminths, and the ecology and genetics of hosts and parasites.Abstract:
Part 1 Microparasites: biology of host-microparasite associations the basic model - statics static aspects of eradication and control the basic model - dynamics dynamic aspects of eradication and control beyond the basic model - empirical evidence of inhomogeneous mixing age-related transmission rates genetic heterogeneity social heterogeneity and sexually transmitted diseases spatial and other kinds of heterogeneity endemic infections in developing countries indirectly transmitted microparasites. Part 2 Macroparasites: biology of host-macroparasite associations the basic model - statics the basic model - dynamics acquired immunity heterogeneity within the human community indirectly transmitted helminths experimental epidemiology parasites, genetic variability, and drug resistance the ecology and genetics of host-parasite associations.read more
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Journal ArticleDOI
Dynamic epidemiology and the market for vaccinations
TL;DR: In this article, a special case in a continuous-time dynamic framework is examined and is found to be efficient, i.e. there is no externality, raising doubts about the suitability of a static approach.
Journal ArticleDOI
Threshold of disease transmission in a patch environment
Wendi Wang,Giuseppe Mulone +1 more
TL;DR: In this paper, an epidemic model is proposed to describe the dynamics of disease spread between two patches due to population dispersal, and it is proved that reproduction number is a threshold of the uniform persistence and disappearance of the disease.
Book ChapterDOI
Adaptive Dynamics of Pathogen–Host Interactions
TL;DR: This chapter explains why the traditional approach of predicting evolutionary outcomes by maximizing the basic reproduction ratio of a disease is not always appropriate.
Journal ArticleDOI
Immuno-epidemiology of human geohelminthiasis: ecological and immunological determinants of worm burden.
TL;DR: Unravelling the interaction between ecology and immunology as determinants of geohelminth worm burden will require simultaneous assessment of both processes via immunoepidemiological study.
Journal ArticleDOI
The natural history of meningococcal carriage and disease.
TL;DR: The prevalence of Neisseria meningitidis carriage is highest in teenagers and lowest in young children, and the secondary peak in disease in teenagers appears to be explained mostly by increased transmission although there is a suggestion that other factors may also contribute.