Open AccessBook
Infectious Diseases of Humans: Dynamics and Control
Roy M. Anderson,Robert M. May +1 more
Reads0
Chats0
TLDR
This book discusses the biology of host-microparasite associations, dynamics of acquired immunity heterogeneity within the human community indirectly transmitted helminths, and the ecology and genetics of hosts and parasites.Abstract:
Part 1 Microparasites: biology of host-microparasite associations the basic model - statics static aspects of eradication and control the basic model - dynamics dynamic aspects of eradication and control beyond the basic model - empirical evidence of inhomogeneous mixing age-related transmission rates genetic heterogeneity social heterogeneity and sexually transmitted diseases spatial and other kinds of heterogeneity endemic infections in developing countries indirectly transmitted microparasites. Part 2 Macroparasites: biology of host-macroparasite associations the basic model - statics the basic model - dynamics acquired immunity heterogeneity within the human community indirectly transmitted helminths experimental epidemiology parasites, genetic variability, and drug resistance the ecology and genetics of host-parasite associations.read more
Citations
More filters
Journal ArticleDOI
Benefits of using multiple first-line therapies against malaria.
TL;DR: An evolutionary-epidemiological modeling framework for malaria is designed and shows that the population-wide use of multiple first-line therapies against malaria yields a better clinical outcome than using a single therapy or a cycling strategy where therapies are rotated, either on a fixed cycling schedule or when resistance levels or treatment failure become too high.
Journal ArticleDOI
Uncertainties regarding dengue modeling in Rio de Janeiro, Brazil
TL;DR: A simple dengue model is developed to answer three questions and concludes that Rio de Janeiro is at risk of a DEN-4 invasion, and stresses the point that epidemiologists, mathematicians, and entomologists need to interact more to find better approaches to the measuring and interpretation of the transmission dynamics of arthropod-borne diseases.
Journal ArticleDOI
Let the Needles Do the Talking! Evaluating the New Haven Needle Exchange
Edward H. Kaplan,Elaine O'Keefe +1 more
TL;DR: This article developed a syringe tracking and testing system that provided data for mathematical models of HIV transmission and found that needle exchange reduced the HIV infection rate among program clients by 33 percent in New Haven, Connecticut.
Journal ArticleDOI
Patch Dynamics and Metapopulation Theory: The Case of Successional Species
TL;DR: A mathematical framework that combines extinction-colonization dynamics with the dynamics of patch succession and the incorporation of seed banks and other dormant life forms is presented, thus broadening patch occupancy dynamics to include sink habitats.
Journal ArticleDOI
The seasonal pattern of dengue in endemic areas: mathematical models of mechanisms
TL;DR: Seasonally-varying parameters such as the latent period of infection in the vector had to be incorporated into the model to generate the correct timing of peak infection prevalence, and changes in such parameters caused seasonal prevalence, but the timing ofpeak prevalence was a result of time delays within the system.