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Infectious Diseases of Humans: Dynamics and Control
Roy M. Anderson,Robert M. May +1 more
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TLDR
This book discusses the biology of host-microparasite associations, dynamics of acquired immunity heterogeneity within the human community indirectly transmitted helminths, and the ecology and genetics of hosts and parasites.Abstract:
Part 1 Microparasites: biology of host-microparasite associations the basic model - statics static aspects of eradication and control the basic model - dynamics dynamic aspects of eradication and control beyond the basic model - empirical evidence of inhomogeneous mixing age-related transmission rates genetic heterogeneity social heterogeneity and sexually transmitted diseases spatial and other kinds of heterogeneity endemic infections in developing countries indirectly transmitted microparasites. Part 2 Macroparasites: biology of host-macroparasite associations the basic model - statics the basic model - dynamics acquired immunity heterogeneity within the human community indirectly transmitted helminths experimental epidemiology parasites, genetic variability, and drug resistance the ecology and genetics of host-parasite associations.read more
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Journal ArticleDOI
On the delayed Ross-Macdonald model for malaria transmission.
TL;DR: It is shown that the basic reproduction number is a decreasing function of both time delays, and prolonging the incubation periods in either humans or mosquitos (via medicine or control measures) could reduce the prevalence of infection.
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Modelling patterns of parasite aggregation in natural populations: trichostrongylid nematode-ruminant interactions as a case study.
TL;DR: The analysis and empirical data indicate that k tracks the increase and subsequent decline in the mean burden with host age, and discusses this result in terms of the degree of heterogeneity in the impact of host immunity or parasite-induced mortality required to shorten the tail of the parasite distribution in older animals.
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Parasite transmission modes and the evolution of virulence
TL;DR: A mathematical model is presented that explores the relationship between transmission patterns and the evolution of virulence for horizontally transmitted parasites when only a single parasite strain can infect each host and demonstrates two important ways in which transmission modes can affect virulence evolution.
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Shining Light on “Dark Winter”
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