Open AccessBook
Infectious Diseases of Humans: Dynamics and Control
Roy M. Anderson,Robert M. May +1 more
Reads0
Chats0
TLDR
This book discusses the biology of host-microparasite associations, dynamics of acquired immunity heterogeneity within the human community indirectly transmitted helminths, and the ecology and genetics of hosts and parasites.Abstract:
Part 1 Microparasites: biology of host-microparasite associations the basic model - statics static aspects of eradication and control the basic model - dynamics dynamic aspects of eradication and control beyond the basic model - empirical evidence of inhomogeneous mixing age-related transmission rates genetic heterogeneity social heterogeneity and sexually transmitted diseases spatial and other kinds of heterogeneity endemic infections in developing countries indirectly transmitted microparasites. Part 2 Macroparasites: biology of host-macroparasite associations the basic model - statics the basic model - dynamics acquired immunity heterogeneity within the human community indirectly transmitted helminths experimental epidemiology parasites, genetic variability, and drug resistance the ecology and genetics of host-parasite associations.read more
Citations
More filters
Journal ArticleDOI
Generality of the Final Size Formula for an Epidemic of a Newly Invading Infectious Disease
Junling Ma,David J. D. Earn +1 more
TL;DR: It is concluded that whenever a new respiratory pathogen emerges, an estimate of the expected magnitude of the epidemic can be made as soon the basic reproduction number ℝ0 can be approximated, and this estimate is likely to be improved only by more accurate estimates of �”0, not by knowledge of any other epidemiological details.
Journal ArticleDOI
Bacterial vaccines and serotype replacement: lessons from Haemophilus influenzae and prospects for Streptococcus pneumoniae.
TL;DR: Mathematical models can be used to elucidate these contrasting outcomes, predict the conditions under which serotype replacement is likely, interpret the results of conjugate vaccine trials, design trials that will better detect serotypes replacement (if it occurs), and suggest factors to consider in choosing the serotype composition of vaccines.
Journal ArticleDOI
Phylogeny and geography predict pathogen community similarity in wild primates and humans
TL;DR: It is found that host relatedness is the best overall predictor of whether two host species share the same pathogens, and for viruses, geographical overlap among neighbouring primate hosts is more important in determining host range.
Journal ArticleDOI
Destabilization of epidemic models with the inclusion of realistic distributions of infectious periods.
TL;DR: This study illustrates how detailed dynamical properties of a model may depend in an important way on the assumptions made in the formulation of the model.
Journal ArticleDOI
Climate Drives the Meningitis Epidemics Onset in West Africa
TL;DR: This study is the first that provides a clear, quantitative demonstration of the connections that exist between MCM epidemics and regional climate variability in Africa and enables the development of an Early Warning Index for meningitis epidemic onset in West Africa.