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Infectious Diseases of Humans: Dynamics and Control
Roy M. Anderson,Robert M. May +1 more
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TLDR
This book discusses the biology of host-microparasite associations, dynamics of acquired immunity heterogeneity within the human community indirectly transmitted helminths, and the ecology and genetics of hosts and parasites.Abstract:
Part 1 Microparasites: biology of host-microparasite associations the basic model - statics static aspects of eradication and control the basic model - dynamics dynamic aspects of eradication and control beyond the basic model - empirical evidence of inhomogeneous mixing age-related transmission rates genetic heterogeneity social heterogeneity and sexually transmitted diseases spatial and other kinds of heterogeneity endemic infections in developing countries indirectly transmitted microparasites. Part 2 Macroparasites: biology of host-macroparasite associations the basic model - statics the basic model - dynamics acquired immunity heterogeneity within the human community indirectly transmitted helminths experimental epidemiology parasites, genetic variability, and drug resistance the ecology and genetics of host-parasite associations.read more
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A theoretical assessment of the effects of vector-virus transmission mechanism on plant virus disease epidemics.
TL;DR: A continuous-time and deterministic model was used to characterize plant virus disease epidemics in relation to virus transmission mechanism and population dynamics of the insect vectors, with clear differences in disease development among the four transmission classes.
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How important is vertical transmission in mosquitoes for the persistence of dengue? Insights from a mathematical model
Ben Adams,Mike Boots +1 more
TL;DR: A mathematical model argues that at infection rates as low as reported from empirical studies, vertical transmission is not an important factor for long term virus persistence and processes such as asymptomatic human dengue cases are more likely to be important in persistence than transmission within the vector population.
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Resource allocation for control of infectious diseases in multiple independent populations: beyond cost-effectiveness analysis.
TL;DR: This paper combines epidemic modeling with optimization techniques to determine the optimal allocation of a limited resource for epidemic control among multiple noninteracting populations and shows that the optimal resource allocation depends on many factors including the size of each population.
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Unexpected epidemic thresholds in heterogeneous networks: the role of disease transmission.
Ronen Olinky,Lewi Stone +1 more
TL;DR: It is shown that epidemic propagation depends equally on the infection scheme as well as the network structure, and Connectivity-dependent infection schemes can yield threshold effects even in scale-free networks where they would otherwise be unexpected.
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On the evolution of virulence and the relationship between various measures of mortality
TL;DR: It is pointed out that relatively deadly pathogens can actually have lower values of α than benign pathogens, demonstrating that α does not, by itself, reflect the extent to which a parasite causes host mortality.