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Infectious Diseases of Humans: Dynamics and Control
Roy M. Anderson,Robert M. May +1 more
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TLDR
This book discusses the biology of host-microparasite associations, dynamics of acquired immunity heterogeneity within the human community indirectly transmitted helminths, and the ecology and genetics of hosts and parasites.Abstract:
Part 1 Microparasites: biology of host-microparasite associations the basic model - statics static aspects of eradication and control the basic model - dynamics dynamic aspects of eradication and control beyond the basic model - empirical evidence of inhomogeneous mixing age-related transmission rates genetic heterogeneity social heterogeneity and sexually transmitted diseases spatial and other kinds of heterogeneity endemic infections in developing countries indirectly transmitted microparasites. Part 2 Macroparasites: biology of host-macroparasite associations the basic model - statics the basic model - dynamics acquired immunity heterogeneity within the human community indirectly transmitted helminths experimental epidemiology parasites, genetic variability, and drug resistance the ecology and genetics of host-parasite associations.read more
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The Effects of Influenza Vaccination of Health Care Workers in Nursing Homes: Insights from a Mathematical Model
TL;DR: The absence of herd immunity in nursing homes implies that vaccination of every additional HCW protects an additional fraction of patients, and a robust linear relationship between the number of HCWs vaccinated and the expected number of influenza virus infections among patients is revealed.
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The Evolutionary and Epidemiological Dynamics of the Paramyxoviridae
TL;DR: Using a Bayesian coalescent approach, the evolutionary and epidemiological dynamics of measles, mumps and canine distemper viruses are inferred and the relatively low levels of genetic diversity in all three viruses is likely to reflect the population bottlenecks that follow recurrent outbreaks.
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Multilevel modelling of the incidence of visceral leishmaniasis in Teresina, Brazil.
Guilherme Loureiro Werneck,Carlos Henrique Nery Costa,Alexander M. Walker,John R. David,Matt P. Wand,James H. Maguire +5 more
TL;DR: Poor socio-economic conditions had an amplifying effect on the association between canine infection and the incidence of human VL, and focusing interventions on areas with characteristics identified by multilevel analysis could be a cost-effective strategy for controlling VL.
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Population dynamics of rapid fixation in cytotoxic T lymphocyte escape mutants of influenza A
TL;DR: A model of recently observed dramatic invasions of cytotoxic T lymphocyte escape mutants in human influenza A finds that the dynamics within a single season of influenza do not provide a realistic description, but a model of the full annual dynamics can offer a possible explanation.
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Harvesting can increase severity of wildlife disease epidemics
Marc Choisy,Pejman Rohani +1 more
TL;DR: It is shown that the interaction between density dependent effects and harvesting can substantially increase both disease prevalence and the absolute number of infectious individuals, which clearly increases the risk of cross-species disease transmission into domestic and livestock populations.