Journal ArticleDOI
Influence of LPS-induced neuroinflammation on acetylcholinesterase activity in rat brain.
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TLDR
In this article, a bilateral intracerebroventricular (ICV) administration of Lipopolysaccharide (LPS) was shown to induce neuroinflammation in different brain regions at different time points after LPS injection.About:
This article is published in Journal of Neuroimmunology.The article was published on 2008-12-15. It has received 84 citations till now. The article focuses on the topics: Proinflammatory cytokine & Neuroinflammation.read more
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Okadaic acid induced neurotoxicity: An emerging tool to study Alzheimer's disease pathology
TL;DR: Okadaic acid (OKA) is one of the main polyether toxins produced by marine microalgae which causes diarrhetic shellfish poisoning and it is a selective and potent inhibitor of serine/threonine phosphatases 1 and 2A induces hyperphosphorylation of tau in vitro and in vivo as mentioned in this paper.
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A study on neuroinflammation and NMDA receptor function in STZ (ICV) induced memory impaired rats
TL;DR: The results suggest that neuroinflammatory markers might be involved in memory impairment via modulating the NMDA receptor in STZ induced memory impaired rats.
Journal ArticleDOI
Effect of choline on antioxidant defenses and gene expressions of Nrf2 signaling molecule in the spleen and head kidney of juvenile Jian carp (Cyprinus carpio var. Jian)
Pei Wu,Wei-Dan Jiang,Wei-Dan Jiang,Yang Liu,Yang Liu,Gangfu Chen,Jun Jiang,Jun Jiang,Shu-Hong Li,Shu-Hong Li,Lin Feng,Lin Feng,Xiao-Qiu Zhou,Xiao-Qiu Zhou +13 more
TL;DR: Dietary choline decreased the oxidant damage and regulated the antioxidant system in immune organs of juvenile Jian carp.
Journal ArticleDOI
Effect of melatonin on neuroinflammation and acetylcholinesterase activity induced by LPS in rat brain.
TL;DR: Melatonin was found to inhibit the LPS induced pro-inflammatory cytokines and oxidative stress in different brain regions and suggest the therapeutic potential of melatonin for neuroinflammation which is an integral part of neurodegenerative disorders.
Journal ArticleDOI
Icariside II attenuates lipopolysaccharide-induced neuroinflammation through inhibiting TLR4/MyD88/NF-κB pathway in rats.
TL;DR: It is concluded that ICS II attenuates LPS-induced neuroinflammation through inhibiting TLR4/MyD88/NF-κB pathway in rats, and it has potential value as a new therapeutic agent to treat neuro inflammation-related diseases, such as AD.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain.
TL;DR: It is revealed that norepinephrine and dopamine are specifically localized in complex systems of neurons in the brain, a finding which lends support to the hypothesis that both amines may be neurotransmitters in the central nervous system.
Journal ArticleDOI
Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
Lyudmila V. Borovikova,Svetlana Ivanova,Minghuang Zhang,Huan Yang,Galina I. Botchkina,Linda R. Watkins,Haichao Wang,Naji N. Abumrad,John W. Eaton,Kevin J. Tracey +9 more
TL;DR: Direct electrical stimulation of the peripheral vagus nerve in vivo during lethal endotoxaemia in rats inhibited TNF synthesis in liver, attenuated peak serum TNF amounts, and prevented the development of shock.
Book
Modern Nutrition in Health and Disease
TL;DR: The fourth edition of Modern Nutrition in Health and Disease follows the organization established in previous volumes, i.e., "Normal Nutrition," "Nutrition in Disease," and "Nut Nutrition in Periods of Physiologic Stress" Each of the 43 chapters is, in essence, a review of a given topic, with primary emphasis on nutritional principles rather than dietetics as mentioned in this paper.
Modern nutrition in health and disease
TL;DR: The concept of nutrition as a clinical subject has reached maturity and is well presented in an excellent book edited by two prominent nutritionists, Drs.