Journal ArticleDOI
Intramolecular low-temperature 1,3-dipolar cycloadditions of nitrones: synthesis of chromano-heterocycles
Gurpinder Singh,Mohan Paul S. Ishar,Vivek K. Gupta,Gurmit Singh,Mohit Kalyan,Surinderjit Singh Bhella +5 more
TLDR
In contrast to the reported facile intramolecular 1,3-dipolar cycloadditions of in-situ generated nitrone on heterocyclic systems, reactions of 2-(N-allyl/crotyl/cinnamyl-anilino)-3-formylchromones with N-phenyl-/methylhydroxylamine under comparable conditions, afford fused isoxazolidines only in low to moderate yields; the corresponding amides derived from rearrangement of in situ generated nitrones are formed as major products REAbout:
This article is published in Tetrahedron.The article was published on 2007-05-28. It has received 21 citations till now. The article focuses on the topics: Nitrone & Crotyl.read more
Citations
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Journal ArticleDOI
Progress in 1,3-dipolar cycloadditions in the recent decade: an update to strategic development towards the arsenal of organic synthesis
Journal ArticleDOI
Applications of allylamines for the syntheses of aza-heterocycles ☆
Somnath Nag,Sanjay Batra +1 more
TL;DR: In this article, a review of the literature concerning the utility of allylamine or substituted allylamines for the synthesis of aza-heterocycles is presented, including nucleophilic reactions, lactamizations, cycloadditions, free radical reactions, cross-couplings and reductive cyclizations.
Journal ArticleDOI
Conversion of nitrosobenzenes to isoxazolidines: an efficient cascade process utilizing reactive nitrone intermediates
TL;DR: Reactive nitrones can be generated directly in situ by an unusual reaction of nitrosobenzene with styrene.
Journal ArticleDOI
Domino routes to substituted benzoindolizines: tandem reorganization of 1,3-dipolar cycloadducts of nitrones with allenic esters/ketones and alternative cycloaddition–palladium catalyzed cyclization pathway
Ashish Kapur,Kamal Kumar,Lakhwinder Singh,Parminder Singh,M. Elango,Venkatesan Subramanian,Vivek K. Gupta,Priyanka Kanwal,Mohan Paul S. Ishar +8 more
TL;DR: In this paper, the formation of benzoindolizines is postulated to involve regioselective addition of 1,3-dipole to C2-C3 π bond of allenic esters/ketones followed by domino transformation of the cycloadducts, which involve an intramolecular aza Diels-Alder reaction in the intermediate C.
Journal ArticleDOI
Substituent-controlled domino-Knoevenagel-hetero Diels—Alder reaction— a one-pot synthesis of polycyclic heterocycles
TL;DR: The reaction of 2-(N-alkenyl-N-aryl)amino-4-oxo-4H-1-benzopyran-3-carbaldehyde with dimedone/Meldrum's acid/4-hydroxycoumarin by heating in ethanol in the presence of pyridine produces polycyclic heterocycles bearing pyrine and pyran rings in a one-pot reaction as discussed by the authors.
References
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Flavonoids as Antioxidants
TL;DR: This review presents the current knowledge on structural aspects and in vitro antioxidant capacity of most common flavonoids as well as in vivo antioxidant activity and effects on endogenous antioxidants.
Journal ArticleDOI
Asymmetric 1,3-Dipolar Cycloaddition Reactions
Book
Cycloaddition reactions in organic synthesis
TL;DR: The Diels-Alder reaction has been studied extensively in the literature, see as mentioned in this paper for a review of some of the main aspects of the Diels Alder reaction and its applications.