Journal ArticleDOI
IR-780 dye loaded tumor targeting theranostic nanoparticles for NIR imaging and photothermal therapy.
Caixia Yue,Peng Liu,Mingbin Zheng,Mingbin Zheng,Pengfei Zhao,Yiqing Wang,Yifan Ma,Lintao Cai +7 more
TLDR
The resulted HF-IR-780 NPs are a potential theranostic agent for imaging-guided cancer therapy and show good monodispersity, significant stability, and excellent molecular targeting to folate receptor over-expressing MCF-7 cells.About:
This article is published in Biomaterials.The article was published on 2013-09-01. It has received 314 citations till now. The article focuses on the topics: Photothermal therapy.read more
Citations
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Near-infrared fluorophores for biomedical imaging
TL;DR: This Review covers recent progress on near-infrared fluorescence imaging for preclinical animal studies and clinical diagnostics and interventions.
Journal ArticleDOI
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
TL;DR: It is anticipated that precisely engineered nanoparticles will emerge as the next-generation platform for cancer therapy and many other biomedical applications.
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Organic molecule-based photothermal agents: an expanding photothermal therapy universe
Hyo Sung Jung,Hyo Sung Jung,Peter Verwilst,Amit Sharma,Jinwoo Shin,Jonathan L. Sessler,Jonathan L. Sessler,Jong Seung Kim +7 more
TL;DR: This tutorial review provides a structured description of the main classes of organic photothermal agents and their characteristics and highlights recent advances in using PTT agents to address various cancers indications.
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Nanoparticle Probes for the Detection of Cancer Biomarkers, Cells, and Tissues by Fluorescence
Alyssa B. Chinen,Chenxia M. Guan,Jennifer R. Ferrer,Stacey N. Barnaby,Timothy J. Merkel,Chad A. Mirkin +5 more
TL;DR: Overcoming Limitations in Nanoparticle Drug Delivery: Triggered, Intravascular Release to Improve Drug Penetration into Tumors and Design Considerations for Tumour-Targeted Nanoparticles.
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Recent advances in the development of organic photothermal nano-agents
TL;DR: Recently, photothermal therapy (PTT) has attracted tremendous attention because of its high efficacy in tumor ablation and minimal damage to normal tissues as mentioned in this paper, and a variety of organic photothermal agents have also emerged in recent years, aiming at replacing their inorganic counterparts which usually are not biodegradable.
References
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Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents
Jonathan F. Lovell,Cheng S. Jin,Cheng S. Jin,Elizabeth Huynh,Elizabeth Huynh,Honglin Jin,Honglin Jin,Chulhong Kim,John L. Rubinstein,Warren C. W. Chan,Weiguo Cao,Lihong V. Wang,Gang Zheng,Gang Zheng +13 more
TL;DR: The development of porphysomes; nanovesicles formed from self-assembled porphyrin bilayers that generated large, tunable extinction coefficients, structure-dependent fluorescence self-quenching and unique photothermal and photoacoustic properties demonstrate the multimodal potential of organic nanoparticles for biophotonic imaging and therapy.
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Toxicity of nanomaterials
Shahriar Sharifi,Shahed Behzadi,Sophie Laurent,M. Laird Forrest,Pieter Stroeve,Morteza Mahmoudi,Morteza Mahmoudi +6 more
TL;DR: A critical review of the biophysicochemical properties of various nanomaterials with emphasis on currently available toxicology data and methodologies for evaluating nanoparticle toxicity suggests that NPs may need to be sequestered into products so that the NPs are not released into the atmosphere during the product's life or during recycling.
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Single-Step Assembly of DOX/ICG Loaded Lipid–Polymer Nanoparticles for Highly Effective Chemo-photothermal Combination Therapy
Mingbin Zheng,Caixia Yue,Yifan Ma,Ping Gong,Pengfei Zhao,Cuifang Zheng,Zonghai Sheng,Pengfei Zhang,Zhaohui Wang,Lintao Cai +9 more
TL;DR: The well-defined DINPs exhibited great potential in targeting cancer imaging and chemo-photothermal therapy and no tumor recurrence was observed after only a single dose of DINP with laser irradiation.
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The influence of surface chemistry and size of nanoscale graphene oxide on photothermal therapy of cancer using ultra-low laser power
TL;DR: The results highlight that both surface chemistry and sizes are critical to the in vivo performance of graphene, and show the promise of using optimized nano-graphene for ultra-effective photothermal treatment, which may potentially be combined with other therapeutic approaches to assist the fight against cancer.
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In vitro and in vivo near-infrared photothermal therapy of cancer using polypyrrole organic nanoparticles.
TL;DR: The majority of currently used PTT agents are inorganic nanomaterials, which usually are not biodegradable and may remain inside the body for long periods of time after systemic administration, but the use of organic nanoparticles, such as porphysome and light-absorbing conductive polymers, as PTT agent has thus attracted attention recently.