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Kinetic modeling on drug release from controlled drug delivery systems.

TLDR
The mathematical modeling can ultimately help to optimize the design of a therapeutic device to yield information on the efficacy of various release models.
Abstract
In this paper we review the mathematical models used to determine the kinetics of drug release from drug delivery systems. The quantitative analysis of the values obtained in dissolution/release rates is easier when mathematical formulae are used to describe the process. The mathematical modeling can ultimately help to optimize the design of a therapeutic device to yield information on the efficacy of various release models.

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Desktop 3D printing of controlled release pharmaceutical bilayer tablets.

TL;DR: The printed formulations were evaluated for physical and mechanical properties such as weight variation, friability, hardness and thickness as a comparison to the commercial tablet and were within acceptable range as defined by the international standards stated in the United States Pharmacopoeia (USP).
Journal ArticleDOI

3D printing of tablets containing multiple drugs with defined release profiles.

TL;DR: This 'polypill' made by a 3D additive manufacture technique demonstrates that complex medication regimes can be combined in a single tablet and that it is viable to formulate and 'dial up' this single tablet for the particular needs of an individual.
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Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs.

TL;DR: The latest works on various novel formulations loaded with various anti‐Alzheimer agents are discussed, which underlines the fact that majority of work related to the nose‐to‐brain delivery of anti‐AD drugs is limited only up to preclinical studies.
Journal ArticleDOI

Slow release coating remedy for nitrogen loss from conventional urea: a review.

TL;DR: The aim of the current review is to develop technical understanding of the conventional and non-conventional coating materials and associated spray coating mechanism for slow release urea production and the potential of starch as the coating material in relation to the coatings tested previously for controlled release fertilizers.
References
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Book

The mathematics of diffusion

John Crank
TL;DR: Though it incorporates much new material, this new edition preserves the general character of the book in providing a collection of solutions of the equations of diffusion and describing how these solutions may be obtained.
Book

Encyclopedia Of Controlled Drug Delivery

TL;DR: The 70 entries offer A-to-Z coverage of controlled drug delivery systems for researchers in the pharmaceutical and biotechnology industries, agriculture companies, medical device companies, clinical research organizations and medical schools.
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