Lifetime and 12-Month Prevalence of Bipolar Spectrum Disorder in the National Comorbidity Survey Replication
Kathleen R. Merikangas,Hagop S. Akiskal,Jules Angst,Paul E. Greenberg,Robert M. A. Hirschfeld,Maria Petukhova,Ronald C. Kessler +6 more
TLDR
This study presents the first prevalence estimates of the BPD spectrum in a probability sample of the United States, and finds subthreshold BPD is common, clinically significant, and underdetected in treatment settings.Abstract:
The estimated lifetime prevalence of bipolar disorder (BPD) in population surveys using structured diagnostic interviews and standardized criteria averages approximately 0.8% for BP-I and 1.1% for BP-II.1-8 Despite this comparatively low prevalence, BPD is a leading cause of premature mortality due to suicide and associated medical conditions such as diabetes and cardiovascular disease.9, 10 BPD also causes widespread role impairment.11, 12 The recurrent nature of manic and depressive episodes often leads to high direct as well as high indirect health care costs.13, 14
BPD might be even more burdensome from a societal perspective due to the fact that sub-threshold bipolar spectrum disorder has seldom been taken into consideration in examining the epidemiology of BPD. Bipolar spectrum disorder includes hypomania without major depression and hypomania of lesser severity or briefer duration than specified in the DSM and ICD criteria. Although the precise definitions are as yet unclear, recent studies suggest that bipolar spectrum disorder might affect as many as 6% of the general population.15, 16 However, bipolar spectrum disorder has not been studied previously in a nationally representative survey of the US. The purpose of the current report is to present the results of such a study based on analysis of the National Comorbidity Survey Replication (NCS-R).17 We estimate prevalence and clinical features of sub-threshold BPD in comparison to BP-I and BP-II.read more
Citations
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The effects of physical exercise in schizophrenia and affective disorders.
Berend Malchow,Daniela Reich-Erkelenz,Viola Oertel-Knöchel,Katriona Keller,Alkomiet Hasan,Andrea Schmitt,Andrea Schmitt,Thomas W. Scheewe,Thomas W. Scheewe,Wiepke Cahn,René S. Kahn,Peter Falkai +11 more
TL;DR: Recommendations for future research strategies are drawn showing that modern therapeutic approaches should include physical exercise as part of a multimodal intervention programme to improve psychopathology and cognitive symptoms in schizophrenia and affective disorders.
Journal ArticleDOI
A systematic review of the global distribution and availability of prevalence data for bipolar disorder
TL;DR: A systematic review of the availability and quality of epidemiological data for bipolar spectrum disorders found no significant differences in prevalence across prevalence types, gender, sample coverage, economic status and bipolar subtype.
Journal ArticleDOI
Behavioural addictions in bipolar disorder patients: Role of impulsivity and personality dimensions
Marco Di Nicola,Daniela Tedeschi,Marianna Mazza,Giovanni Martinotti,Desiree Harnic,Valeria Catalano,Angelo Bruschi,Gino Pozzi,Pietro Bria,Luigi Janiri +9 more
TL;DR: BAs are more frequent in bipolar patients than in healthy controls and are related to higher impulsivity levels and character immaturity, the first study investigating the prevalence of behavioural addictions in BD showing a significant association with mood disorders.
Journal ArticleDOI
An update on the debated association between ADHD and bipolar disorder across the lifespan.
TL;DR: Results point towards a meaningful association between ADHD and BD, going beyond symptomatic similarities, but future research needs to account for heterogeneity of BD, making clear distinctions between classical episodic forms of BD and broader conceptualisations of the disorder characterised by irritability and emotional lability when evaluating the relationship with ADHD.
Journal ArticleDOI
Monotherapy With Major Antihypertensive Drug Classes and Risk of Hospital Admissions for Mood Disorders
Angela H. Boal,Daniel J. Smith,Linsay McCallum,Scott Muir,Rhian M. Touyz,Anna F. Dominiczak,Sandosh Padmanabhan +6 more
TL;DR: The exploratory findings suggest possible differential effects of antihypertensive medications on mood that merits further study: calcium antagonists and &bgr;-blockers may be associated with increased risk, whereas angiotensin-converting enzyme inhibitors and angiotENSin receptor blockers may beassociated with a decreased risk of mood disorders.
References
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