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Journal ArticleDOI

Management of gastric cancer in Asia: resource-stratified guidelines

TLDR
This work aims to provide a stepwise strategy for management of gastric cancer applicable to different levels of health-care resources in Asian countries, using the categories of basic, limited, enhanced, and maximum level.
Abstract
Summary Gastric cancer is the fourth most common cancer globally, and is the second most common cause of death from cancer worldwide. About three-quarters of newly diagnosed cases in 2008 were from Asian countries. With a high mortality-to-incidence ratio, management of gastric cancer is challenging. We discuss evidence for optimum management of gastric cancer in aspects of screening and early detection, diagnosis, and staging; endoscopic and surgical intervention; and the concepts of perioperative, postoperative, and palliative chemotherapy and use of molecularly targeted therapy. Recommendations are formulated on the basis of the framework provided by the Breast Health Global Initiative, using the categories of basic, limited, enhanced, and maximum level. We aim to provide a stepwise strategy for management of gastric cancer applicable to different levels of health-care resources in Asian countries.

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Construction of a metabolomics profile of arsenic trioxide effect in gastric carcinoma cell line SGC7901

TL;DR: The metabolomics data from this study, in combination with previous transcriptomics and proteomics data, could serve as valuable resources for the understanding of the specific antitumor mechanism of ATO treatment.
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Multi-Modality Treatment for Patients With Metastatic Gastric Cancer: A Real-World Study in China.

TL;DR: Multi-modality treatments offer a survival benefit for patients with metastatic GC, and patients who received palliative gastrectomy or metastasectomy had a longer survival than those who only received intraperitoneal chemotherapy or radiotherapy.
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Disparities in gastric cancer screening among people with disabilities: a national registry-linkage study in South Korea.

TL;DR: In spite of the availability of national gastric cancer screening program, there are significant disparities in gastriccancer screening participation, especially among people with severe disabilities and those with renal failure or brain-related/mental disabilities.
Journal ArticleDOI

Is preoperative staging enough to guide lymph node dissection in clinically early gastric cancer

TL;DR: Comprehensive evaluation based on MDCT, preoperative histological type, and tumor size is an effective method to predict lymph node metastasis (LNM) and guide tailored LN dissection for cEGC.
References
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Journal ArticleDOI

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008.

TL;DR: The results for 20 world regions are presented, summarizing the global patterns for the eight most common cancers, and striking differences in the patterns of cancer from region to region are observed.
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Perioperative Chemotherapy versus Surgery Alone for Resectable Gastroesophageal Cancer

TL;DR: In patients with operable gastric or lower esophageal adenocarcinomas, a perioperative regimen of ECF decreased tumor size and stage and significantly improved progression-free and overall survival.
Journal ArticleDOI

Management of Helicobacter pylori infection—the Maastricht IV/ Florence Consensus Report

TL;DR: In this 4th edition of the Maastricht consensus report aspects related to the clinical role of H pylori were looked at again in 2010, with recommendations to guide doctors involved in the management of this infection associated with various clinical conditions.
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Capecitabine and oxaliplatin for advanced esophagogastric cancer.

TL;DR: Capecitabine and oxaliplatin are as effective as fluorouracil and cisplatin, respectively, in patients with previously untreated esophagogastric cancer, in a two-by-two design.
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