Journal ArticleDOI
Management of gastric cancer in Asia: resource-stratified guidelines
Lin Shen,Yan Shen Shan,Huang Ming Hu,Timothy J. Price,Bhawna Sirohi,Kun-Huei Yeh,Yi-Hsin Yang,Takeshi Sano,Han-Kwang Yang,Xiaotian Zhang,Sook Ryun Park,Masashi Fujii,Yoon-Koo Kang,Li-Tzong Chen,Li-Tzong Chen +14 more
TLDR
This work aims to provide a stepwise strategy for management of gastric cancer applicable to different levels of health-care resources in Asian countries, using the categories of basic, limited, enhanced, and maximum level.Abstract:
Summary Gastric cancer is the fourth most common cancer globally, and is the second most common cause of death from cancer worldwide. About three-quarters of newly diagnosed cases in 2008 were from Asian countries. With a high mortality-to-incidence ratio, management of gastric cancer is challenging. We discuss evidence for optimum management of gastric cancer in aspects of screening and early detection, diagnosis, and staging; endoscopic and surgical intervention; and the concepts of perioperative, postoperative, and palliative chemotherapy and use of molecularly targeted therapy. Recommendations are formulated on the basis of the framework provided by the Breast Health Global Initiative, using the categories of basic, limited, enhanced, and maximum level. We aim to provide a stepwise strategy for management of gastric cancer applicable to different levels of health-care resources in Asian countries.read more
Citations
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Nivolumab in patients with advanced gastric or gastro-oesophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACTION-2): a randomised, double-blind, placebo-controlled, phase 3 trial
Yoon-Koo Kang,Narikazu Boku,Taroh Satoh,Min Hee Ryu,Yee Chao,Ken Kato,Hyun Cheol Chung,Jen-Shi Chen,Kei Muro,Won Ki Kang,Kun-Huei Yeh,Takaki Yoshikawa,Sang Cheul Oh,Li Yuan Bai,Takao Tamura,Keun Wook Lee,Yasuo Hamamoto,Jong Gwang Kim,Keisho Chin,Do Youn Oh,Keiko Minashi,Jae Yong Cho,Masahiro Tsuda,Li-Tzong Chen,Li-Tzong Chen +24 more
TL;DR: In this phase 3 study, the survival benefits indicate that nivolumab might be a new treatment option for heavily pretreated patients with advanced gastric or gastro-oesophageal junction cancer.
Journal ArticleDOI
Cause-specific mortality for 240 causes in China during 1990-2013: a systematic subnational analysis for the Global Burden of Disease Study 2013.
Maigeng Zhou,Haidong Wang,Jun Zhu,Wanqing Chen,Linhong Wang,Shiwei Liu,Yichong Li,Lijun Wang,Yunning Liu,Peng Yin,Jiangmei Liu,Shicheng Yu,Feng Tan,Ryan M Barber,Matthew M Coates,Daniel Dicker,Maya S Fraser,Diego Gonzalez-Medina,Hannah Hamavid,Yuantao Hao,Guoqing Hu,Guohong Jiang,Haidong Kan,Alan D. Lopez,Michael R. Phillips,Michael R. Phillips,Jun She,Theo Vos,Xia Wan,Gelin Xu,Lijing L. Yan,Chuanhua Yu,Yong Zhao,Yingfeng Zheng,Xiaonong Zou,Mohsen Naghavi,Yu Wang,Christopher J L Murray,Gonghuan Yang,Xiaofeng Liang +39 more
TL;DR: The most common non-communicable diseases, including ischaemic heart disease, stroke, chronic obstructive pulmonary disease, and cancers (liver, stomach, and lung), contributed much more to YLLs in 2013 compared with 1990, and road injuries have become a top ten cause of death in all provinces in mainland China.
Journal ArticleDOI
Worldwide trends in gastric cancer mortality (1980–2011), with predictions to 2015, and incidence by subtype
Ana Ferro,Bárbara Peleteiro,Matteo Malvezzi,Cristina Bosetti,Paola Bertuccio,Fabio Levi,Eva Negri,Carlo La Vecchia,Carlo La Vecchia,Nuno Lunet +9 more
TL;DR: Despite the favourable mortality trends worldwide, in some countries the declines are becoming less marked, and the predictions for 2015 show that a levelling off of rates is expected in the USA and a few other countries.
Journal ArticleDOI
Effectiveness of the Korean National Cancer Screening Program in Reducing Gastric Cancer Mortality
Jae Kwan Jun,Kui Son Choi,Hoo Yeon Lee,Mina Suh,Boyoung Park,Seung Hoon Song,Kyu-Won Jung,Chan Wha Lee,Il Ju Choi,Eun Cheol Park,Dukhyoung Lee +10 more
TL;DR: Within the Korean National Cancer Screening Program, patients who received an upper endoscopy were less likely to die from gastric cancer; no associations were found for UGI series.
Journal ArticleDOI
Genetics of gastric cancer.
Mairi H. McLean,Emad M. El-Omar +1 more
TL;DR: The genetic basis of gastric cancer will offer insights into its pathogenesis, help identify new biomarkers and novel treatment targets, aid prognostication and could be central to developing individualized treatment strategies in the future.
References
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Journal ArticleDOI
Asia-Pacific consensus guidelines on gastric cancer prevention.
Kwong Ming Fock,Nicholas J. Talley,Paul Moayyedi,Richard H. Hunt,Takeshi Azuma,Kentaro Sugano,Shu Dong Xiao,Shiu Kum Lam,Khean-Lee Goh,Tsutomu Chiba,Naomi Uemura,Jae G. Kim,Nayoung Kim,Tiing Leong Ang,Varocha Mahachai,Hazel M. Mitchell,Abdul Aziz Rani,Jyh-Ming Liou,Ratha korn Vilaichone,Jose D. Sollano +19 more
TL;DR: This work critically evaluated strategies for preventing gastric cancer in the Asia–Pacific region and found that conventional and innovative approaches to prevention are likely to be effective.
Journal ArticleDOI
The benefit of mass eradication of Helicobacter pylori infection: a community-based study of gastric cancer prevention
Yi-Chia Lee,Tony Hsiu Hsi Chen,Han-Mo Chiu,Chia-Tung Shun,Hung-Chi Chiang,Tzeng-Ying Liu,Ming-Shiang Wu,Jaw-Town Lin +7 more
TL;DR: Population-based eradication of H pylori infection has led to a significant reduction in gastric atrophy at the expense of increased oesophagitis and the ultimate benefit in reducing gastric cancer incidence and its mortality should be validated by a further long-term follow-up.
Journal ArticleDOI
Imaging in Local Staging of Gastric Cancer: A Systematic Review
Robert M. Kwee,Thomas C. Kwee +1 more
TL;DR: EUS remains the first-choice imaging modality in preoperative T staging of gastric cancer and MDCT and MRI achieve similar results in terms of diagnostic accuracy in T staging and in assessing serosal involvement.
Journal ArticleDOI
Gastric atrophy and intestinal metaplasia before and after Helicobacter pylori eradication: a meta-analysis.
TL;DR: It is shown that eradication of H. pylori results in significant improvement in GA in the corpus but not in the antrum; it also does not improve gastric mucous IM.
Journal ArticleDOI
Comparison of endoscopic ultrasonography and conventional endoscopy for prediction of depth of tumor invasion in early gastric cancer.
TL;DR: EUS may not be necessary routinely, and conventional endoscopy may be sufficient for determining the optimal therapeutic strategy, especially in relation to endoscopic resection for early gastric cancer.