MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0
TLDR
An advanced version of the Molecular Evolutionary Genetics Analysis software, which currently contains facilities for building sequence alignments, inferring phylogenetic histories, and conducting molecular evolutionary analysis, is released, which enables the inference of timetrees, as it implements the RelTime method for estimating divergence times for all branching points in a phylogeny.Abstract:
We announce the release of an advanced version of the Molecular Evolutionary Genetics Analysis (MEGA) software, which currently contains facilities for building sequence alignments, inferring phylogenetic histories, and conducting molecular evolutionary analysis. In version 6.0, MEGA now enables the inference of timetrees, as it implements the RelTime method for estimating divergence times for all branching points in a phylogeny. A new Timetree Wizard in MEGA6 facilitates this timetree inference by providing a graphical user interface (GUI) to specify the phylogeny and calibration constraints step-by-step. This version also contains enhanced algorithms to search for the optimal trees under evolutionary criteria and implements a more advanced memory management that can double the size of sequence data sets to which MEGA can be applied. Both GUI and command-line versions of MEGA6 can be downloaded from www.megasoftware.net free of charge.read more
Citations
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Studies on the Virome of the Entomopathogenic Fungus Beauveria bassiana Reveal Novel dsRNA Elements and Mild Hypervirulence.
TL;DR: A comparison of virus-free and virus-infected isogenic lines derived from an exemplar B. bassiana isolate revealed a mild hypervirulent effect of mycoviruses on the growth of their host isolate and on its pathogenicity against the greater wax moth Galleria mellonella, highlighting for the first time the potential of myCovirus as enhancers of biocontrol agents.
Journal ArticleDOI
Identification and overexpression of gibberellin 2-oxidase (GA2ox) in switchgrass (Panicum virgatum L.) for improved plant architecture and reduced biomass recalcitrance
Wegi A. Wuddineh,Wegi A. Wuddineh,Mitra Mazarei,Mitra Mazarei,Ji-Yi Zhang,Charleson R. Poovaiah,Charleson R. Poovaiah,David G. J. Mann,David G. J. Mann,Angela Ziebell,Angela Ziebell,Robert W. Sykes,Robert W. Sykes,Mark F. Davis,Mark F. Davis,Michael K. Udvardi,Charles Neal Stewart,Charles Neal Stewart +17 more
TL;DR: The results suggest that overexpression of GA2ox genes in switchgrass is a feasible strategy to improve plant architecture and reduce biomass recalcitrance for biofuel.
Journal ArticleDOI
Discovery of Novel Bat Coronaviruses in South China That Use the Same Receptor as Middle East Respiratory Syndrome Coronavirus
Chu Ming Luo,Ning Wang,Xing-Lou Yang,Hai Zhou Liu,Wei Zhang,Bei Li,Ben Hu,Cheng Peng,Qi Bin Geng,Guang Jian Zhu,Fang Li,Zhengli Shi +11 more
TL;DR: 89 novel lineage C betacoronaviruses in eight bat species are discovered and evidence of a MERS-related CoV derived from the great evening bat that uses the same host receptor as human Mers-CoV is provided.
Journal ArticleDOI
Viral nervous necrosis in gilthead sea bream ( Sparus aurata ) caused by reassortant betanodavirus RGNNV/SJNNV: an emerging threat for Mediterranean aquaculture
Anna Toffan,Francesco Pascoli,Tobia Pretto,Tobia Pretto,Valentina Panzarin,Miriam Abbadi,Alessandra Buratin,Rosita Quartesan,Daniel Gijón,Francesc Padrós +9 more
TL;DR: Information strongly suggests that RGNNV/SJNNV betanodavirus possesses a particular tropism to sea bream, which can pose a new and unexpected threat to the Mediterranean aquaculture.
Journal ArticleDOI
VRS2 regulates hormone-mediated inflorescence patterning in barley
Helmy M. Youssef,Helmy M. Youssef,Kai Eggert,Ravi Koppolu,Ahmad M. Alqudah,Naser Poursarebani,Arash Fazeli,Shun Sakuma,Shun Sakuma,Akemi Tagiri,Twan Rutten,Geetha Govind,Udda Lundqvist,Andreas Graner,Takao Komatsuda,Nese Sreenivasulu,Nese Sreenivasulu,Thorsten Schnurbusch +17 more
TL;DR: The molecular and hormonal role of Six-rowed spike 2 (Vrs2), which encodes a SHORT INTERNODES transcriptional regulator during barley inflorescence and shoot development, is elucidated and a link between the SHI protein family and sucrose metabolism during organ growth and development is established.
References
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Journal ArticleDOI
MEGA5: Molecular Evolutionary Genetics Analysis using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods
Koichiro Tamura,Daniel S. Peterson,Nicholas Peterson,Glen Stecher,Masatoshi Nei,Sudhir Kumar +5 more
TL;DR: The newest addition in MEGA5 is a collection of maximum likelihood (ML) analyses for inferring evolutionary trees, selecting best-fit substitution models, inferring ancestral states and sequences, and estimating evolutionary rates site-by-site.
Journal ArticleDOI
MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment
TL;DR: An overview of the statistical methods, computational tools, and visual exploration modules for data input and the results obtainable in MEGA is provided.
Book
The Neutral Theory of Molecular Evolution
TL;DR: The neutral theory as discussed by the authors states that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants, which has caused controversy ever since.
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