MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0
TLDR
An advanced version of the Molecular Evolutionary Genetics Analysis software, which currently contains facilities for building sequence alignments, inferring phylogenetic histories, and conducting molecular evolutionary analysis, is released, which enables the inference of timetrees, as it implements the RelTime method for estimating divergence times for all branching points in a phylogeny.Abstract:
We announce the release of an advanced version of the Molecular Evolutionary Genetics Analysis (MEGA) software, which currently contains facilities for building sequence alignments, inferring phylogenetic histories, and conducting molecular evolutionary analysis. In version 6.0, MEGA now enables the inference of timetrees, as it implements the RelTime method for estimating divergence times for all branching points in a phylogeny. A new Timetree Wizard in MEGA6 facilitates this timetree inference by providing a graphical user interface (GUI) to specify the phylogeny and calibration constraints step-by-step. This version also contains enhanced algorithms to search for the optimal trees under evolutionary criteria and implements a more advanced memory management that can double the size of sequence data sets to which MEGA can be applied. Both GUI and command-line versions of MEGA6 can be downloaded from www.megasoftware.net free of charge.read more
Citations
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The fungal-specific β-glucan-binding lectin FGB1 alters cell-wall composition and suppresses glucan-triggered immunity in plants
Stephan Wawra,Philipp H. Fesel,Heidi Widmer,Malte Timm,Jürgen Seibel,Lisa Leson,Leona Kesseler,Robin Nostadt,Magdalena Hilbert,Gregor Langen,Alga Zuccaro,Alga Zuccaro +11 more
TL;DR: It is shown that the FGB1 gene from the root endophyte Piriformospora indica encodes for a secreted fungal-specific β-glucan-binding lectin with dual function, which has the potential to both alter fungal cell wall composition and properties and to efficiently suppress β- glucans triggered immunity in plant hosts.
Journal ArticleDOI
Abiotic Stresses Downregulate Key Genes Involved in Nitrogen Uptake and Assimilation in Brassica juncea L.
TL;DR: Observations indicate that expression of most of the genes is adversely affected under abiotic stress conditions, particularly under prolonged stress exposure (24h), which may be one of the reasons of reduction in plant growth and development under abiotics stresses.
Journal ArticleDOI
A Specialist Herbivore Pest Adaptation to Xenobiotics Through Up-Regulation of Multiple Cytochrome P450s
TL;DR: The data suggest that xenobiotic adaptation in this specialist herbivore is through up-regulation of multiple P450s that are potentially involved in detoxifying both pesticide and plant allelochemicals.
Journal ArticleDOI
Map-based Cloning and Characterization of the BPH18 Gene from Wild Rice Conferring Resistance to Brown Planthopper (BPH) Insect Pest.
Hyeonso Ji,Sung-Ryul Kim,Yul-Ho Kim,Jung-Pil Suh,Hyang-Mi Park,Nese Sreenivasulu,Gopal Misra,Suk-Man Kim,Sherry Lou Hechanova,Hakbum Kim,Gang-Seob Lee,Ung-Han Yoon,Tae Ho Kim,Hyemin Lim,Suk-Chul Suh,Jungil Yang,Gynheung An,Kshirod K. Jena +17 more
TL;DR: The BPH18 gene from the BPH-resistant introgression line derived from the wild rice species Oryza australiensis was cloned to facilitate elucidation of the molecular mechanism of BPH resistance and the identified novel alleles to fast track breeding BPH resistant rice cultivars.
Journal ArticleDOI
Genetic diversity and evolutionary insights of respiratory syncytial virus A ON1 genotype: global and local transmission dynamics
Venkata R. Duvvuri,Andrea Granados,Paul Rosenfeld,Justin Bahl,Alireza Eshaghi,Jonathan B. Gubbay +5 more
TL;DR: It is suggested that local epidemics exhibit similar underlying evolutionary and epidemiological dynamics to that of the persistent global RSV-A ON1 population, and the importance of continual molecular surveillance of RSV in order to gain a better understanding of epidemics.
References
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Journal ArticleDOI
MEGA5: Molecular Evolutionary Genetics Analysis using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods
Koichiro Tamura,Daniel S. Peterson,Nicholas Peterson,Glen Stecher,Masatoshi Nei,Sudhir Kumar +5 more
TL;DR: The newest addition in MEGA5 is a collection of maximum likelihood (ML) analyses for inferring evolutionary trees, selecting best-fit substitution models, inferring ancestral states and sequences, and estimating evolutionary rates site-by-site.
Journal ArticleDOI
MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment
TL;DR: An overview of the statistical methods, computational tools, and visual exploration modules for data input and the results obtainable in MEGA is provided.
Book
The Neutral Theory of Molecular Evolution
TL;DR: The neutral theory as discussed by the authors states that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants, which has caused controversy ever since.
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