MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0
TLDR
An advanced version of the Molecular Evolutionary Genetics Analysis software, which currently contains facilities for building sequence alignments, inferring phylogenetic histories, and conducting molecular evolutionary analysis, is released, which enables the inference of timetrees, as it implements the RelTime method for estimating divergence times for all branching points in a phylogeny.Abstract:
We announce the release of an advanced version of the Molecular Evolutionary Genetics Analysis (MEGA) software, which currently contains facilities for building sequence alignments, inferring phylogenetic histories, and conducting molecular evolutionary analysis. In version 6.0, MEGA now enables the inference of timetrees, as it implements the RelTime method for estimating divergence times for all branching points in a phylogeny. A new Timetree Wizard in MEGA6 facilitates this timetree inference by providing a graphical user interface (GUI) to specify the phylogeny and calibration constraints step-by-step. This version also contains enhanced algorithms to search for the optimal trees under evolutionary criteria and implements a more advanced memory management that can double the size of sequence data sets to which MEGA can be applied. Both GUI and command-line versions of MEGA6 can be downloaded from www.megasoftware.net free of charge.read more
Citations
More filters
Journal ArticleDOI
Phylogenetic relationships of corallinaceae (Corallinales, Rhodophyta): taxonomic implications for reef-building corallines.
TL;DR: A new, more complete, five‐marker molecular phylogeny of the family Corallinaceae, order Corallinales, shows a paraphyletic grouping of seven well‐supported monophyletic clades.
Journal ArticleDOI
The legacy of a vanished sea: a high level of diversification within a European freshwater amphipod species complex driven by 15 My of Paratethys regression.
TL;DR: The results point out that investigations of the historical aspect of cryptic diversity in other taxa may help in a general understanding of the origins of freshwater invertebrate fauna of Europe.
Journal ArticleDOI
Accumulation of Human-Adapting Mutations during Circulation of A(H1N1)pdm09 Influenza Virus in Humans in the United Kingdom
Ruth A. Elderfield,Simon J. Watson,Alexandra Godlee,Walt E. Adamson,Catherine Thompson,Jake Dunning,Mirian Fernandez-Alonso,Deena Blumenkrantz,Tracy Hussell,Maria Zambon,Peter J. M. Openshaw,Paul Kellam,Wendy S. Barclay +12 more
TL;DR: Multiple evolutionary changes that in combination over time increased the virus's ability to infect human cells may explain the remarkable ability of A(H1N1)pdm09 virus to continue to circulate despite widespread immunity and the apparent increase in severity of influenza over successive waves of infection.
Journal ArticleDOI
Effects of PGPR microbial inoculants on the growth and soil properties of Avena sativa, Medicago sativa, and Cucumis sativus seedlings
TL;DR: In this article, the effects of the PGPR microbial inoculants on the growth, physiology, and soil properties of oat (Avena sativa), alfalfa (Medicago sativa) and cucumber (Cucumis sativus) seedlings were verified by a pot experiment.
Journal ArticleDOI
The wax gourd genomes offer insights into the genetic diversity and ancestral cucurbit karyotype
Dasen Xie,Yuanchao Xu,Jinpeng Wang,Wenrui Liu,Qian Zhou,Luo Shaobo,Wu Huang,Xiaoming He,Qing Li,Qingwu Peng,Xueyong Yang,Jiaqing Yuan,Jigao Yu,Xiyin Wang,William J. Lucas,Sanwen Huang,Biao Jiang,Zhonghua Zhang +17 more
TL;DR: It is shown that the wax gourd genome has the most ancestral karyotype among cucurbits and candidate genes which contribute to large fruit size are identified by comparative and population genomics analyses.
References
More filters
Journal ArticleDOI
MEGA5: Molecular Evolutionary Genetics Analysis using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods
Koichiro Tamura,Daniel S. Peterson,Nicholas Peterson,Glen Stecher,Masatoshi Nei,Sudhir Kumar +5 more
TL;DR: The newest addition in MEGA5 is a collection of maximum likelihood (ML) analyses for inferring evolutionary trees, selecting best-fit substitution models, inferring ancestral states and sequences, and estimating evolutionary rates site-by-site.
Journal ArticleDOI
MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment
TL;DR: An overview of the statistical methods, computational tools, and visual exploration modules for data input and the results obtainable in MEGA is provided.
Book
The Neutral Theory of Molecular Evolution
TL;DR: The neutral theory as discussed by the authors states that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants, which has caused controversy ever since.
Related Papers (5)
The neighbor-joining method: a new method for reconstructing phylogenetic trees.
Naruya Saitou,Masatoshi Nei +1 more