scispace - formally typeset
Open AccessJournal ArticleDOI

MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0

TLDR
An advanced version of the Molecular Evolutionary Genetics Analysis software, which currently contains facilities for building sequence alignments, inferring phylogenetic histories, and conducting molecular evolutionary analysis, is released, which enables the inference of timetrees, as it implements the RelTime method for estimating divergence times for all branching points in a phylogeny.
Abstract
We announce the release of an advanced version of the Molecular Evolutionary Genetics Analysis (MEGA) software, which currently contains facilities for building sequence alignments, inferring phylogenetic histories, and conducting molecular evolutionary analysis. In version 6.0, MEGA now enables the inference of timetrees, as it implements the RelTime method for estimating divergence times for all branching points in a phylogeny. A new Timetree Wizard in MEGA6 facilitates this timetree inference by providing a graphical user interface (GUI) to specify the phylogeny and calibration constraints step-by-step. This version also contains enhanced algorithms to search for the optimal trees under evolutionary criteria and implements a more advanced memory management that can double the size of sequence data sets to which MEGA can be applied. Both GUI and command-line versions of MEGA6 can be downloaded from www.megasoftware.net free of charge.

read more

Content maybe subject to copyright    Report

Citations
More filters
Journal ArticleDOI

Connections between the Atlantic and the Amazonian forest avifaunas represent distinct historical events

TL;DR: In this article, the authors combined phylogenetic data with distributional data using a supermatrix approach in order to depict the historical connection dynamics between these biomes for New World suboscines and provided the first general temporal and spatial model of how the Atlantic and Amazonian forests were connected in the past.
Journal ArticleDOI

The 2014 Ebola virus disease outbreak in West Africa

TL;DR: A new outbreak of the Ebola virus disease (EVD) was reported in Guinea on 23 March 2014, which began in December 2013 in Guinee Forestiere (Forested Guinea), the eastern sector of the Republic of Guinea as mentioned in this paper.
Journal ArticleDOI

WGS accurately predicts antimicrobial resistance in Escherichia coli

TL;DR: WGS can provide comprehensive resistance genotypes and is capable of accurately predicting resistance phenotypes, making it a valuable tool for surveillance, and the ability to accurately predict resistance suggest that WGS may be used as a screening tool in selecting anti-infective therapy, especially as costs drop and methods improve.
Journal ArticleDOI

Differential specificity between closely related corals and abundant Endozoicomonas endosymbionts across global scales.

TL;DR: This work demonstrates that both corals harbor Endozoicomonas bacteria as their prevalent symbiont, and contributes to the factors underlying microbiome specificity and adds detail to coral holobiont functioning.
Journal ArticleDOI

Fungal Planet description sheets: 469-557

Pedro W. Crous, +111 more
- 21 Dec 2016 - 
TL;DR: Novel species of fungi described in this study include those from various countries as follows: Apiognomonia lasiopetali on Lasiopetalum sp.
References
More filters
Journal ArticleDOI

MEGA5: Molecular Evolutionary Genetics Analysis using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

TL;DR: The newest addition in MEGA5 is a collection of maximum likelihood (ML) analyses for inferring evolutionary trees, selecting best-fit substitution models, inferring ancestral states and sequences, and estimating evolutionary rates site-by-site.
Journal ArticleDOI

MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment

TL;DR: An overview of the statistical methods, computational tools, and visual exploration modules for data input and the results obtainable in MEGA is provided.
Book

The Neutral Theory of Molecular Evolution

Motoo Kimura
TL;DR: The neutral theory as discussed by the authors states that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants, which has caused controversy ever since.
Related Papers (5)