Methods to detect nitric oxide and its metabolites in biological samples
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TLDR
The methods described in this review are not an exhaustive or comprehensive discussion of all methods available for the detection of NO but rather a description of the most commonly used and practical methods which allow accurate and sensitive quantification of NO products/metabolites in multiple biological matrices under normal physiological conditions.About:
This article is published in Free Radical Biology and Medicine.The article was published on 2007-09-01 and is currently open access. It has received 766 citations till now.read more
Citations
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Fluorescent and luminescent probes for measurement of oxidative and nitrosative species in cells and tissues: progress, pitfalls, and prospects.
TL;DR: Progress in the development of probes for "reactive oxygen and nitrogen" species, emphasizing the caution needed in their use is reviewed, with a focus on probes based on reduced dyes.
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Carbon Nanotube Chemical Sensors
TL;DR: This review is a comprehensive description of the parameters that give rise to the sensing capabilities of CNT-based sensors and the application of C NT-based devices in chemical sensing and their prospects for commercialization.
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Antibacterial and Anti-Inflammatory pH-Responsive Tannic Acid-Carboxylated Agarose Composite Hydrogels for Wound Healing.
TL;DR: The fabrication of novel carboxylated agarose/tannic acid hydrogel scaffolds cross-linked with zinc ions for the pH-controlled release of tannic acids display cytocompatibility, antibacterial, and anti-inflammatory characteristics that make them promising candidates for wound dressings.
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Pure dietary flavonoids quercetin and (−)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy men
Wai Mun Loke,Jonathan M. Hodgson,Julie M. Proudfoot,Allan J. McKinley,Ian B. Puddey,Kevin D. Croft +5 more
TL;DR: Dietary flavonoids, such as quercetin and (-)-epicatechin, can augment nitric oxide status and reduce endothelin-1 concentrations and may thereby improve endothelial function.
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Liver ischemia/reperfusion injury: Processes in inflammatory networks—A review
Mahmoud Abu-Amara,Mahmoud Abu-Amara,Shi Yu Yang,Niteen Tapuria,Barry Fuller,Brian R. Davidson,Brian R. Davidson,Alexander M. Seifalian,Alexander M. Seifalian +8 more
TL;DR: Recent findings pertaining to the aforementioned factors of liver IR are discussed, and areas with gaps in knowledge are highlighted, necessitating further research.
References
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Journal Article
Nitric oxide: physiology, pathophysiology, and pharmacology
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Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly.
J. S. Beckman,Willem H. Koppenol +1 more
TL;DR: The rapid diffusion of nitric oxide between cells allows it to locally integrate the responses of blood vessels to turbulence, modulate synaptic plasticity in neurons, and control the oscillatory behavior of neuronal networks.
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Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation.
Kenyatta Cosby,Kristine S. Partovi,Jack H. Crawford,Rakesh P. Patel,Christopher D. Reiter,Sabrina Martyr,Benjamin K. Yang,Myron A. Waclawiw,Gloria Zalos,Xiuli Xu,Kris T. Huang,Howard Shields,Daniel B. Kim-Shapiro,Alan N. Schechter,Richard O. Cannon,Mark T. Gladwin +15 more
TL;DR: It is suggested that nitrite represents a major bioavailable pool of NO, and a new physiological function for hemoglobin as a nitrite reductase is described, potentially contributing to hypoxic vasodilation.
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Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils
Jason P. Eiserich,Jason P. Eiserich,Milena Hristova,Carroll E. Cross,A. Daniel Jones,Bruce A. Freeman,Barry Halliwell,Barry Halliwell,Albert van der Vliet +8 more
TL;DR: The data reveal that NO2− may regulate inflammatory processes through oxidative mechanisms, perhaps by contributing to the tyrosine nitration and chlorination observed in vivo.
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S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds
Jonathan S. Stamler,Daniel I. Simon,John A. Osborne,Mark E. Mullins,Omar Jaraki,Thomas Michel,David J. Singel,Joseph Loscalzo +7 more
TL;DR: It is demonstrated that S-nitroso proteins form readily under physiologic conditions and possess EDRF-like effects of vasodilation and platelet inhibition, suggesting that S -nitrosothiol groups in proteins may serve as intermediates in the cellular metabolism of NO and raise the possibility of an additional type of cellular regulatory mechanism.