Journal ArticleDOI
miR-425-5p as an exosomal biomarker for metastatic prostate cancer
Michele Patrícia Rode,Adny Henrique Silva,Julia Cisilotto,Daiane Rosolen,Tânia Beatriz Creczynski-Pasa +4 more
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TLDR
In this paper, the expression profile of exosomal microRNAs (miRNAs) derived from metastatic prostate cancer (mPCa) cell lines (LNCaP and PC-3) was evaluated by miRNA microarray analysis.About:
This article is published in Cellular Signalling.The article was published on 2021-11-01. It has received 13 citations till now. The article focuses on the topics: Prostate cancer & LNCaP.read more
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Dynamic Role of Exosome microRNAs in Cancer Cell Signaling and Their Emerging Role as Noninvasive Biomarkers
TL;DR: Exosomes are extracellular vesicles that originate from endosomes and are released by all cells irrespective of their origin or type as discussed by the authors , and they play an important role in cell communication and can act in an autocrine, endocrine, or paracrine fashion.
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Circulating and extracellular vesicle-derived microRNAs as biomarkers in bone-related diseases
TL;DR: The role of microRNAs as biomarkers in bone-related diseases, with a specific focus on osteoporosis and osteosarcoma, has been discussed in this article .
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Non-Coding RNAs Derived from Extracellular Vesicles Promote Pre-Metastatic Niche Formation and Tumor Distant Metastasis
Kun Zhang,Jinwu Peng,Lifang Yang +2 more
TL;DR: In this article , a review of the role and mechanism of non-coding RNA derived from extracellular vesicles in mediating tumor-distant metastasis, and its predictive value for tumor diagnosis and evaluation as a potential target for anti-tumor metastasis is presented.
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Analysis of relative gene expression data using real-time quantitative pcr and the 2(-delta delta c(t)) method
TL;DR: The 2-Delta Delta C(T) method as mentioned in this paper was proposed to analyze the relative changes in gene expression from real-time quantitative PCR experiments, and it has been shown to be useful in the analysis of realtime, quantitative PCR data.
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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Freddie Bray,Jacques Ferlay,Isabelle Soerjomataram,Rebecca L. Siegel,Lindsey A. Torre,Ahmedin Jemal +5 more
TL;DR: A status report on the global burden of cancer worldwide using the GLOBOCAN 2018 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer, with a focus on geographic variability across 20 world regions.
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Cancer statistics, 2020.
TL;DR: Slow momentum for some cancers amenable to early detection is juxtaposed with notable gains for other common cancers, and it is notable that long‐term rapid increases in liver cancer mortality have attenuated in women and stabilized in men.
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Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
TL;DR: It is shown that exosomes contain both mRNA and microRNA, which can be delivered to another cell, and can be functional in this new location, and it is proposed that this RNA is called “exosomal shuttle RNA” (esRNA).
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Extracellular vesicles: exosomes, microvesicles, and friends.
TL;DR: This review focuses on the characterization of EVs and on currently proposed mechanisms for their formation, targeting, and function.