Journal ArticleDOI
miR-425-5p as an exosomal biomarker for metastatic prostate cancer
Michele Patrícia Rode,Adny Henrique Silva,Julia Cisilotto,Daiane Rosolen,Tânia Beatriz Creczynski-Pasa +4 more
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TLDR
In this paper, the expression profile of exosomal microRNAs (miRNAs) derived from metastatic prostate cancer (mPCa) cell lines (LNCaP and PC-3) was evaluated by miRNA microarray analysis.About:
This article is published in Cellular Signalling.The article was published on 2021-11-01. It has received 13 citations till now. The article focuses on the topics: Prostate cancer & LNCaP.read more
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Liquid biopsy: Exosomal microRNAs as novel diagnostic and prognostic biomarkers in cancer
K. Preethi,Sushmaa Chandralekha Selvakumar,K Rossi,Selvaraj Jayaraman,Deusdedit Tusubira,Durairaj Sekar +5 more
TL;DR: In this paper , a review of exosomal miRNAs (liquid biopsy) as biomarkers in the diagnosis and prognosis of various cancers is presented. But the authors focus on the use of liquid biopsies as a supplement to biopsy, as it enables disease progression to be detected months before clinical and radiographic confirmation.
Journal ArticleDOI
Liquid biopsy: Exosomal microRNAs as novel diagnostic and prognostic biomarkers in cancer
K. Preethi,Sushmaa Chandralekha Selvakumar,K Rossi,Selvaraj Jayaraman,Deusdedit Tusubira,Durairaj Sekar +5 more
TL;DR: In this paper , a review of exosomal miRNAs (liquid biopsy) as biomarkers in the diagnosis and prognosis of various cancers is presented. But the authors focus on the use of liquid biopsies as a supplement to biopsy, as it enables disease progression to be detected months before clinical and radiographic confirmation.
Journal ArticleDOI
Molecular Biomarkers in Cancer
TL;DR: Improvement in the field of cancer biomarkers is, however, needed to overcome the scientific challenge of developing new biomarkers with greater sensitivity, specificity, and positive predictive value.
Journal ArticleDOI
Identification of Diagnostic Markers for Breast Cancer Based on Differential Gene Expression and Pathway Network
TL;DR: It is shown that the difference of gene expression level is important for the diagnosis of breast cancer, and 23 breast cancer diagnostic markers are identified, which provides valuable information for clinical diagnosis and basic treatment experiments.
Journal ArticleDOI
Pro-angiogenic effect of PC-3 exosomes in endothelial cells in vitro.
Anne Natalie Prigol,Michele Patrícia Rode,Adny Henrique Silva,Julia Cisilotto,Tânia Beatriz Creczynski-Pasa +4 more
TL;DR: In this article, the angiogenic potential of exosomes released from Pca cell lines with distinctive profiles of androgen response through exosome isolation, microscopy and uptake, functional assays follow up by microarray, RT-qPCR and bioinformatics analysis.
References
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Predicting effective microRNA target sites in mammalian mRNAs
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Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids
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PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools
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Impact of Particle Size and Polydispersity Index on the Clinical Applications of Lipidic Nanocarrier Systems.
M. Danaei,M Dehghankhold,Sara Ataei,F Hasanzadeh Davarani,R. Javanmard,A Dokhani,Saied Nouri Khorasani,Mohammad Reza Mozafari +7 more
TL;DR: This review highlights the significance of size and PDI in the successful design, formulation and development of nanosystems for pharmaceutical, nutraceutical and other applications.