Journal ArticleDOI
Neurocritical Care Updates in Cerebrovascular Disease
Ruchira M. Jha,Kevin N. Sheth +1 more
About:
This article is published in Stroke.The article was published on 2021-06-11. It has received 0 citations till now. The article focuses on the topics: Neurointensive care.read more
References
More filters
Journal ArticleDOI
Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors
Stuart J. Connolly,Mark Crowther,John W. Eikelboom,C. Michael Gibson,John T. Curnutte,John H. Lawrence,Patrick Yue,Michele D. Bronson,Genmin Lu,Pamela B. Conley,Peter Verhamme,Jeannot Schmidt,Saskia Middeldorp,Alexander T. Cohen,Jan Beyer-Westendorf,Pierre Albaladejo,Jose Lopez-Sendon,Andrew M. Demchuk,Daniel J. Pallin,Mauricio Concha,Shelly Goodman,Janet M. Leeds,Sonia Souza,Deborah M. Siegal,Elena Zotova,Brandi Meeks,Sadia Ahmad,Juliet Nakamya,Truman J. Milling,Annexa Investigators +29 more
TL;DR: In patients with acute major bleeding associated with the use of a factor Xa inhibitor, treatment with andexanet markedly reduced anti–factor Xa activity, and 82% of patients had excellent or good hemostatic efficacy at 12 hours, as adjudicated according to prespecified criteria.
Journal ArticleDOI
Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial.
Michael D. Hill,Mayank Goyal,Bijoy K Menon,Raul G. Nogueira,Ryan A McTaggart,Andrew M. Demchuk,Alexandre Y Poppe,Brian H Buck,Thalia S Field,Dar Dowlatshahi,Brian van Adel,Richard H. Swartz,Ruchir Shah,Eric Sauvageau,Charlotte Zerna,Johanna M. Ospel,Manish Joshi,Mohammed A. Almekhlafi,Karla J Ryckborst,M.W. Lowerison,Kathy Heard,David Garman,Diogo C Haussen,Shawna Cutting,Shelagh B. Coutts,Daniel Roy,Jeremy L Rempel,A. Rohr,Daniela Iancu,Daniela Iancu,Demetrios J Sahlas,Amy Y.X. Yu,Thomas Devlin,Ricardo A. Hanel,Volker Puetz,F L Silver,Bruce C.V. Campbell,René Chapot,Jeanne Teitelbaum,Jennifer L Mandzia,Timothy Kleinig,David Turkel-Parrella,Donald V. Heck,Michael E Kelly,Aditya Bharatha,Oh Young Bang,Ashutosh P Jadhav,Rishi Gupta,Donald Frei,Jason W Tarpley,Cameron G. McDougall,Staffan Holmin,Joung-Ho Rha,Ajit S Puri,Marie-Christine Camden,Götz Thomalla,Hana Choe,Stephen J Phillips,Joseph L Schindler,John Thornton,Simon Nagel,Ji Hoe Heo,Sung Il Sohn,Marios-Nikos Psychogios,Ronald F Budzik,Sidney Starkman,C Martin,Paul A Burns,Sean M. Murphy,George A Lopez,Joey English,Michael Tymianski,Andrew M. Demchuk,Philip A. Barber,Eric E. Smith,Simerpreet Bal,Suresh Subramaniam,Steven Peters,Phillippe Couillard,Gary Klein,Peter Stys,Bijoy K. Menon,S B Coutts,Mohammed A Almekhlafi,Michael D. Hill,John Wong,Alim P. Mitha,Muneer Eesa,William Morrish,Saad Alqatani,Nima Kashani,Johanna Ospel,Prasanna Venkatesan,Erika Teleg,Amith Sitaram,Brett H. Graham,Stephen van Gaal,Aimen Moussaddy,Debabrata Chakraborty,Nicholas Maraj,Andrew Loockey,Shuo Chen,Ravinder Singh,Abdulaziz Alsultan,Ria Asuncion,Dominic Tse,Darshan Doshi,Ondrej Volny,Piyush Ojha,Ankur Wadhwa,Martha Marko,Nishita Singh,Sanchea Wasyliw,Karla J Ryckborst,Carol Kenney,Supriya Save,Anitha Jambula,Nancy Newcommon,Gavin Hull,Darcy Blackstock,Sharon Kiszczak,Leslie Zimmel,Michelle F. Wright,Cari Jahraus,Linda B. Andersen,Shelly Bohn,Joseph Paul,Oiao Zhang,Craig Doram,Mark Lowerison,Andrea Hanley,Lori Campbell,Ashley Ure,Francis Taylor,Dominic Hul,Samuel Wiebe,Marina Saluzzi,Nicole Blenkin,Richard Frayne,Brian Buck,Kenneth Butcher,Ashfaq Shuaib,Thomas Jeerakathil,Glen C. Jickling,Derek Emery,Jeremy L. Rempel,Richard Owen,Robert Ashforth,Tom Yeo,Trevor Kotylak,Cian O'Kelly,Michael Chow,Muzaffer Siddiqui,Maher Saqqur,Atlantic D’Souza,Mar Lloret,Asif Butt,Ali Zohair Nomani,Hayrapet Kalashyan,Sibi Thirunavukkarasu,Juline Jabs,Paige Fairall,Lori Piquette,Stephen J. Phillips,A. Laine Green,Gordon Gubitz,Jens Heidenreich,Thien J. Huynh,Jai Jai Shiva Shankar,William Maloney,Robert Vandorpe,Matthias H. Schmidt,Gwynedd E. Pickett,Adrienne Weeks,Judith Jarrett,Debbie MacDonald,Joanna Arsenault,Ruth Kinnear,Jennifer Mandzia,Michael Mayich,Melfort Boulton,Maria Bullrich,Sebastian Fridman,Ruba Kiwan,Donald H. Lee,Stephen Lownie,Alexander V. Khaw,Sachin Pandey,Manas Sharma,Luciano A. Sposato,Kevin Wade,Beth Beauchamp,Lindsay Lambourn,Belinda Amato-Marziali,Alexandre Y Poppe,Nicole Daneault,Yan Deschaintre,Laura C. Gioia,Grégory Jacquin,Céline Odier,Christian Stapf,Jean Raymond,Alain Weill,Marlène Lapierre,Nadia Jadil,Judlène Jolteus,Mark Angle,Mathew Hannouche,Mohamed K. Badawy,Justin Letourneau,Maria Cortes,Grant Linnell,Donateela Tampieri,Lucy Vieira,Catherine Legault,Liam Durcan,Angela Moore,Erin Cole,Claire Magnussen,Kristiana Salmon,Salma Khalil,Isabelle Desloges,Lindsay Waxman,Wynne Abdon,Sonia Lai,Michel Shamy,Grant Stotts,Dylan Blacquiere,Howard Lesiuk,Aiman Quateen,Brian Drake,Brian Dewar,Zeinab Daham,Michael Kelly,Gary R. Hunter,Lissa Peeling,Ruth Whelan,Aaron Garner,Lilian Urroz,Sharleen Maley,Frank L. Silver,Leanne K. Casaubon,Aleksandra Pikula,M. Campo,Joanna D. Schaafsma,Cheryl Jaigobin,Timo Krings,Vitor Mendes Pereira,Ronit Agid,Richard I. Farb,Libby Kalman,Anne Cayley,Janice Williams,Tim Stewart,Karen Misquitta,Daniel Selchen,Thomas R. Marotta,Dipanka Sarma,Walter Montanera,Juluan Spears,Gustavo Saposnik,Pawel Kostyrko,Yangmei Li,Carmen Parra-Farina,Jose Danilo B. Diestro,Steve Verreault,Ariane Mackey,Marie-Eve Audet,Geneviève Milot,Pascale Lavoie,Jean-Luc Gariépy,Karine Collard,Annette Haché,Brian Van Adel,Demetrios J. Sahlas,Ahmed Alshanbari,Josephine Baldwin,Luciana Catanese,Bing Chen,Danielle de Sa Boasquevisque,Aviraj Deshmukh,Jordan Knapman,Shana Lamers,Ramiro Larrazabal,Susan MacMillan,Lauren Mai,Alicia Mattia,Sumiti Nayar,Kuan Ng,Wieslaw Oczkowski,Kanjana S Perera,Mays Shawawrah,Ashkan Shoamanesh,Gita Sobhi,Nabeel Syed,Noran Taher,Cheyanne Vandervelde,Di Wang Pharm,Thalia S. Field,Philip Teal,Oscar R. Benavente,Laura A. B. Wilson,Sharanpal Mann,Samuel Yip,Colleen Murphy,Manraj K.S. Heran,Axel Rohr,Fabio Settecase,Gary Redekop,Charles S. Haw,Genoveva Maclean,Karina Murray,Rosalin Chiu,Alana M. Flexman,Eilidh Strecha,Yolanda Gayton,Judy Yip,Richard Swartz,Mark I. Boulos,David J. Gladstone,Amy Yu,Julia Hopyan,Houman Khosravani,Herbert Manosalva Alzate,Alisia Southwell,Maneesha Kamra,Kaitlyn Lopes,Arunima Kapoor,Leodante da Costa,Victor X. D. Yang,Erin Dyer,Ruchir Shah,Brenda Knowles,Jennifer Nichols,Jennifer Patterson,Krista Cope,Lee Dickerson,Katrina Barton,Kimberly Gray,Ticey Massengale,Melanie Miller,Cindy Simpson,Sabrina Walker,Chlin Tennyson-Yemm,Thomas Devlin,Donald Frei,R Bellon,Benjamin Atchie,Ian Kaminsky,Duandelyn Wilson,Nicolle Schraeder,Eric Arias,Lisa Kodis,Mark Talley,Alex Edinger,Tiffany Talley,Ita Dempsey,Laurie Williams,Scott Williams,Sonny Kupniewski,Brad Fasbinder,Joanna Snead,Larami MacKenzie,Davi Weisman,Osman Kozak,Qaisar A. Shah,Dan Gzesh,Kandan Kulandaivel,John Khoury,Brad Klein,Patricia Bussinger,Lisa Griffin,Ashley dePalmo,Cynthia Oliva,Tudor G Jovin,Cynthia L. Kenmuir,Brian T. Jankowitz,Bradley A. Gross,Marcelo Rocha,Matthew Starr,Merritt Brown,Christine Hawkes,Kavit Shah,Danoushka Tememe,Gregory Walker,Pratit Patel,Bradley Klein,Habibullah Ziayee,Kaustubh Limaye,Lisa Baxendell,Vicki Gilchrist,Patricia Feineigle,Kelsea Toseki Haibach,Cathy Van Every,Shashyat Desai,Maryam Zulfiqar,Linda Gibson,Sean Barrett,Karthikeyan Arcot,Steven DiCrescento,Jeffrey Farkas,Gregory Filipowski,Jennifer A. Frontera,Danielle Joset,Jeremy Liff,Erica Scher,Cameron M. McDougall,Cheryl Kelly,Akshal Patel,Stephen J. Monteith,Kunakorn Atchaneeyasakul,Adrian Burgos,Janice Anne Chua,Nathan Gaines,Ileana Grunberg,Judy Guzy,Zuolu Liu,Neil Maluste,Lucas Ramirez,Latisha Sharma,Morry Brown,Colin McDonald,Mateo Calderon,Mitch Hargis,Christina Roels,Prabhu Emmady,Talat Alvi,Ryan A McTaggart,Mahesh V Jayaraman,Shawna S. Cutting,Wendy Smith,Susan Foley,Gino Paolucci,Richard Has,Katie Quinn,Lindsey Fuller,Rebecca Brierley,Christina Watkins,Nicole Demir,George A. Lopez,Alejandro Vargas,Nicholas Osteraas,Becky Holtz,Ricardo Hanel,Amin Aghaebrahim,Mohamad Chmayssani,Neeraj Naval,Jason Day,Scott Dellorso,Benjamin Ludwig,Derek Schemmel,Nancy Ebreo,Karen Bell,Lanai Lewis,Marjorie Delucia,Raul G Nogueira,Michael Frankel,Nirav Bhatt,Nicolas Bianchi,Aaron Anderson,Samir Belagaje,Bernardo Liberato,Srikant Rangaraju,Alhamza R Al-Bayati,Jonathan A. Grossberg,Leah Craft,Kiva M Schindler,Erin Schaad,Meagan Schultz,Lorretta Southerly,Shannon Doppelheuer,Jacquelyn Charlton,Jason Faggard,Zuzana Barbret,Ethan DukSoo Han,Robin G. Walters,Jaydevsinh Dolia,Sleiman El-Jamal,Brendan Eby,Yasir Saleem,Harrison Pearl,Kishan Patel,Haseeb Rahman,Reema Butt,Stephen English,Ajit S. Puri,M Howk,Jasmeet Singh,Francesco Massari,Katyucia de Macedo Rodrigues,Anna Luisa Kühn,Nobl Barazangi,Nick Telischak,Warren Kim,Josh Ross,Nata DeVole,Jessica Redford,Milena Ferreira,Katie Ponting,Helen Shen,Ann Bedenk,Susila Patel,Julia Fernandess,Michael Ke,Ilanit Spokoyny,Billy Gao,David C. Tong,Charlene Chen,Christine Wong,Jessica Choe,Coleman O. Martin,Debbie Summers,Christine Boutwell,Karin Olds,Suzanne Crandall,John Eatman,Naveed Akhtar,William E. Holloway,Jared Halpin,Brett Donegan,Joseph Schindler,David Y. Hwang,Emily J. Gilmore,Nils H Petersen,Kevin N. Sheth,Stacy C Brown,Rachel Beekman,Benjamin George,Firas Kaddouh,Guido J. Falcone,Charles R. Wira,Charles C. Matouk,Caitlin Loomis,Hardik Amin,Hans Christoph Stretz,Reshma Narula,Adam Jasne,Lauren H Sansing,Tijil Agarwal,Sara Jasak,Briana Fontaine,Zachary A. King,Lindsey Kuohn,Hailey Orgass,Megan Leary,Joan Nye,Kelsey Halbert,Karin Nystrom,Kaile Neuschatz,Dawn Petrucci,Anna Coppola,Jason Tarpley,Treasure Joyce,Sam Hou,Mark Umekubo,Catrice Nakamura,Renee Ovando,Diana Zuniga,Yih Lin Nien,Fernando Mayor Basto,Allison Arch,Laura Jong,William Conrad,Tara Abbott,Jay Yao,Scott Caganap,John Jordan,George Teitelbaum,Robert Darflinger,Marianne Bain,Ronald F. Budzik,Jennifer Czerniak,Katherine Groezinger,William Hicks,Omran Kaskar,Brian Katz,Aaron Loochtan,Peter Pema,Vivek Rai,Nirav Vora,Amanda Brown,Diane Goodman,Barb Danenbergs,Monica Gossett,Jong-Won Chung,Pyoung Jeon,Keon Ha Kim,Yun Jeong Lim,Hyo Suk Nam,Young Dae Kim,Hyungjong Park,In Gun Hwang,Wooseok Ha,Jin Kyo Choi,Kyungsun Jeong,Hee-Kwon Park,Cindy Yoon,Bo-Kyung Kim,Chang-Hyun Kim,Joonsang Yoo,Jeong-Ho Hong,S.-H. Kim,Moonkyung Choi,Hyoeun Bae,Jun Seok Lee,Jae-Joon Lee,Go-Eun Jun,Sujeong Jeon,B Campbell,Peter Mitchell,Nawaf Yassi,Stephen N. Davis,Geoffrey A. Donnan,Mark W Parsons,Bernard Yan,Richard Dowling,Steven Bush,Teddy Y. Wu,Darshan Shah,Henry Zhao,Patrick Salvaris,Fana Alemseged,Felix C Ng,Cameron Williams,Anna H. Balabanski,Angela Dos Santos,Jo-Lyn Ng,Amy A. McDonald,David C. Jackson,Jessica Tsoleridis,Lauren Pesavento,Timothy John Kleinig,Roy Drew Nurs,Jennifer Cranefield,Rebecca Scroop,Lavenia Cagi,Jackson Harvey,Michael J. Waters,Robert Brennan,Alan O'Hare,Sarah Power,David Williams,Karl Boyle,Barry Moynihan,Ann-Marie Liddy,Margaret Large,Ailbhe Cullen,Roisin Walsh,Emma Martin,Julie Lynch,Sinéad McElroy,Sarah Coveney,Caroline Deegan,Gillian Horgan,Peter J. Kelly,Aoife Laffan,Yudy Llamas-Osorio,Catherine Lynch,Peter Mac Mahon,Michael Marnane,John Gerald McCabe,Paul A Burns,Suzanne Tauro,Sarah Cuddy,Ian Rennie,Graham Smyth,Peter Flynn,Ivan Wiggam,Enda Kerr,Patricia Gordon,Patricia Fearon,Geralt Roberts,Cathy Patterson,Karen Adams,Brian J. Wells,Margaret McFarland,Tiago Moreira,Christina Sjöstrand,Michael V. Mazya,Håkan Almqvist,Nils Wahlgren,Anna Steinberg,Charith Cooray,Einar E. Eriksson,Magnus Thorén,Boris Keselman,Niaz Ahmed,Åke Holmberg,Maria Axelsson,Annika Berglund,Amir Golsari,Julia Hoppe,Milani Deb-Chatterji,Bastian Cheng,Ewgenia Barrow,Eckhard Schlemm,Iris Lettow,Märit Jensen,Dagmar Otto,Kirsten Jaramillo,Hannes Appelbohm,Jens Fiehler,Maxim Bester,Michael Schönfeld,Caspar Brekenfeld,Brigitte Holst,Ginette Wortmann,Friederike Koch,Johannes Gerber,Andrij Abramyuk,Daniel Kaiser,Simon Winzer,Alexandra Prakapenia,Lars-Peder Pallesen,Timo Siepmann,Kristian Barlinn,Kathrin Haase,Angela Sauer,Jan Liman,Alex Brehm,Volker Maus,Nicole Hollstein,Annika Reinke,Gustav Neitz,Marlena Schnieder,Margret Schwarz,Allam Ibrahim,Julia Müller,Stefanie Meister,Berit Bäumle,Sara Pilgram-Pastor,Marta Wallocha,Michael Stauder,Ekin Celik,Paul Stracke,Nicole Müller,Ralph Weber,Roland Velktamp,Peter A. Ringleb,Miriam Heyse,Hemasse Amiri,Sibu Mundiyanapurath,Min Chen,Elisabeth Bevrle,Perdita Beck,Markus A Möhlenbruch,Alphonse Potvin,Cameron Harris,Chong Wang,Corey Adams,Diana Mayor,Dave Garman,Davis Chau,Jane Wu,Janet Lunn,Liat Bermanis,Lucy Teyes,Marc Constant,Maria Galsim,Michael Helbin,Michelle Leroux,Nicole Felix,Nilima Bendre,Sandra Cuthbert,Steve Brokx,Yichuan Zhang,Trudy Lingham,Yatika Kohli,Michael Salter,Joseph Liebeschuetz,Frieder Hofmann,John Constant,Tom Soeder,Kara Snoke,Monica Bologa,Kimberly Stahl,Maria Graziewicz +776 more
TL;DR: Nerinetide did not improve the proportion of patients achieving good clinical outcomes after endovascular thrombectomy compared with patients receiving placebo, and this trial is registered with ClinicalTrials.gov, NCT02930018.
Journal ArticleDOI
Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomized, placebo-controlled trial
Ryan Matthews,Amanda Young +1 more
Journal ArticleDOI
Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial
Nikola Sprigg,Nikola Sprigg,Katie Flaherty,Jason P. Appleton,Rustam Al-Shahi Salman,Dániel Bereczki,Maia Beridze,Hanne Christensen,Alfonso Ciccone,Ronan Collins,Anna Członkowska,Robert A. Dineen,Lelia Duley,Juan José Egea-Guerrero,Timothy J. England,Kailash Krishnan,Kailash Krishnan,Ann Charlotte Laska,Zhe Kang Law,Zhe Kang Law,Zhe Kang Law,Şerefnur Öztürk,Stuart J. Pocock,Ian Roberts,Thompson G. Robinson,Christine Roffe,David J. Seiffge,Polly Scutt,Jegan Thanabalan,David J. Werring,David K. Whynes,Philip M.W. Bath,Philip M.W. Bath +32 more
TL;DR: The tranexamic acid can prevent death due to bleeding after trauma and postpartum haemorrhage in adults with stroke due to intracerebral haemoryrhage as mentioned in this paper.
Journal ArticleDOI
Restoration of brain circulation and cellular functions hours post-mortem
Zvonimir Vrselja,Stefano G. Daniele,John Silbereis,Francesca Talpo,Francesca Talpo,Yury M. Morozov,André M. M. Sousa,Brian S. Tanaka,Mario Skarica,Mihovil Pletikos,Mihovil Pletikos,Navjot Kaur,Zhen W. Zhuang,Zhao Liu,Rafeed Alkawadri,Rafeed Alkawadri,Albert J. Sinusas,Stephen R. Latham,Stephen G. Waxman,Nenad Sestan +19 more
TL;DR: It is demonstrated that under appropriate conditions the isolated, intact large mammalian brain possesses an underappreciated capacity for restoration of microcirculation and molecular and cellular activity after a prolonged post-mortem interval.