Nonfasting Triglycerides, Low-Density Lipoprotein Cholesterol, and Heart Failure Risk: Two Cohort Studies of 113 554 Individuals.
TLDR
Stepwise higher concentrations of nonfasting triglycerides were associated with stepwise higher risk of heart failure; however, concentrations of low-density lipoprotein cholesterol were not associated with risk ofHeart failure in the general population.Abstract:
Objective—The prevalence of heart failure is increasing in the aging population, and heart failure is a disease with large morbidity and mortality. There is, therefore, a need for identifying modif...read more
Citations
More filters
Journal ArticleDOI
The forgotten lipids: Triglycerides, remnant cholesterol, and atherosclerotic cardiovascular disease risk
TL;DR: An overview of the biology, epidemiology, and genetics of TGs and ASCVD is provided; current and novel TG-lowering therapies under development are discussed; and many novel drugs are in development and have shown impressive efficacy in lowering TG levels.
Journal ArticleDOI
Remnant Cholesterol, Not LDL Cholesterol, Is Associated With Incident Cardiovascular Disease
Olga Castañer,Xavier Pintó,Isaac Subirana,Antonio J. Amor,Emilio Ros,Álvaro Hernáez,Miguel Ángel Martínez-González,Dolores Corella,Jordi Salas-Salvadó,Ramon Estruch,José Lapetra,Enrique Gómez-Gracia,Ángel M. Alonso-Gómez,Miquel Fiol,Lluis Serra-Majem,Emili Corbella,David Benaiges,José V. Sorlí,Miguel Ruiz-Canela,Nancy Babio,Lucas Tojal Sierra,Emilio Ortega,Montserrat Fitó +22 more
TL;DR: In overweight or obese subjects at high cardiovascular risk, levels of triglycerides and remnant-C, but not cholesterol transported in triglyceride-rich lipoproteins (remnant cholesterol) were associated with cardiovascular outcomes independent of other risk factors.
Journal ArticleDOI
Dyslipidemia and cardiovascular disease risk among the MASHAD study population.
Mahshad Hedayatnia,Zahra Asadi,Reza Zare-Feyzabadi,Mahdiyeh Yaghooti-Khorasani,Hamideh Ghazizadeh,Roshanak Ghaffarian-Zirak,Abolfazl Nosrati-Tirkani,Maryam Mohammadi-Bajgiran,Mohadese Rohban,Fatemeh Sadabadi,Hamid Reza Rahimi,Marzieh Ghalandari,Mohammad-Seddigh Ghaffari,Asa Yousefi,Elnaz Pouresmaeili,Mohammad-Reza Besharatlou,Mohsen Moohebati,Gordon A. Ferns,Habibollah Esmaily,Majid Ghayour-Mobarhan +19 more
TL;DR: TC baseline level was significantly associated with the risk of MI among men and after adjusting for confounding factors, a significant direct association only remained between TC and MI risk in men.
Journal ArticleDOI
Lipoproteins and lipids in cardiovascular disease: from mechanistic insights to therapeutic targeting.
TL;DR: This review comprehensively discusses low- and high-densitylipoprotein cholesterol, lipoprotein (a), triglycerides as well as fatty acids and derivatives in the context of cardiovascular disease, providing mechanistic insights into their role in pathological processes impacting on cardiovascular disease.
Journal ArticleDOI
Highlighting Residual Atherosclerotic Cardiovascular Disease Risk.
TL;DR: High prevalence of ASCVD can be observed in type 2 diabetic patients with elevated levels of plasma triglycerides and low levels of HDL (high-density lipoprotein) cholesterol (HDL-C) and levels of glycated hemoglobin outside the target range, as well as in patients who for other reasons have elevated triglycerides, or increased inflammation.
References
More filters
Journal ArticleDOI
2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC.
Piotr Ponikowski,Adriaan A. Voors,Stefan D. Anker,Héctor Bueno,John G.F. Cleland,Andrew J.S. Coats,Volkmar Falk,José Ramón González-Juanatey,Veli-Pekka Harjola,Ewa A. Jankowska,Mariell Jessup,Cecilia Linde,Petros Nihoyannopoulos,John Parissis,Burkert Pieske,Jillian P. Riley,Giuseppe M.C. Rosano,Luis M. Ruilope,Frank Ruschitzka,Frans H. Rutten,Peter van der Meer,Gerasimos Filippatos,John J.V. McMurray,Victor Aboyans,Stephan Achenbach,Stefan Agewall,Nawwar Al-Attar,John Atherton,Johann Bauersachs,A. John Camm,Scipione Carerj,Claudio Ceconi,Antonio Coca,Perry M. Elliott,Çetin Erol,Justin A. Ezekowitz,Covadonga Fernández-Golfín,Donna Fitzsimons,Marco Guazzi,Maxime Guenoun,Gerd Hasenfuss,Gerhard Hindricks,Arno W. Hoes,Bernard Iung,Tiny Jaarsma,Paulus Kirchhof,Juhani Knuuti,Philippe Kolh,Stavros Konstantinides,Mitja Lainscak,Patrizio Lancellotti,Gregory Y.H. Lip,Francesco Maisano,Christian Mueller,Mark C. Petrie,Massimo F Piepoli,Silvia G. Priori,Adam Torbicki,Hiroyuki Tsutsui,Dirk J. van Veldhuisen,Stephan Windecker,Clyde W. Yancy,José Luis Zamorano +62 more
TL;DR: Authors/Task Force Members: Piotr Ponikowski* (Chairperson) (Poland), Adriaan A. Voors* (Co-Chair person) (The Netherlands), Stefan D. Anker (Germany), Héctor Bueno (Spain), John G. F. Cleland (UK), Andrew J. S. Coats (UK)
Journal ArticleDOI
2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Clyde W. Yancy,Mariell Jessup,Biykem Bozkurt,Javed Butler,Donald E. Casey,Mark H. Drazner,Gregg C. Fonarow,Stephen A. Geraci,Tamara B. Horwich,James L. Januzzi,Maryl R. Johnson,Edward K. Kasper,Wayne C. Levy,Frederick A. Masoudi,Patrick E. McBride,John J.V. McMurray,Judith E. Mitchell,Pamela N. Peterson,Barbara Riegel,Flora Sam,Lynne W. Stevenson,W.H. Wilson Tang,Emily J. Tsai,Bruce L. Wilkoff +23 more
TL;DR: In this article, Anderson et al. proposed a new FAHA Chair, Jeffrey L. Anderson, MD, FACC, FAHA, Chair-Elect, Alice K. Jacobs et al., this article and Biykem Bozkurt.
Journal ArticleDOI
Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group
J. Shepherd,Stuart M. Cobbe,Ian Ford,C. G. Isles,AR Lorimer,Peter W. Macfarlane,J. H. Mckillop,Christopher J. Packard +7 more
TL;DR: Treatment with pravastatin significantly reduced the incidence of myocardial infarction and death from cardiovascular causes without adversely affecting the risk of death from noncardiovascular causes in men with moderate hypercholesterolemia and no history of my Cardiac Infarction.
Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
J Ames S Hepherd,S Tuart M. C Obbe,I An F Ord,C Hristopher G. I Sles,A. R Oss L Orimer,P Eter W. M Acfarlane,J Ames H. M C K Illop,C Hristopher J. P Ackard,S Tudy G Roup +8 more
TL;DR: In this article, a double-blind study was designed to determine whether the administration of pravastatin to men with hypercho-lesterolemia and no history of myocardial infarction correlated with the combined incidence of nonfatal mycardial in-farction and death from coronary heart disease.
Journal ArticleDOI
Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studies.
TL;DR: Based on combined data from prospective studies, triglyceride is a risk factor for cardiovascular disease for both men and women in the general population, independent of HDL cholesterol.
Related Papers (5)
Triglycerides and cardiovascular disease
Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management
M. John Chapman,Henry N. Ginsberg,Pierre Amarenco,Felicita Andreotti,Jan Borén,Alberico L. Catapano,Olivier S. Descamps,Edward A. Fisher,Petri T. Kovanen,Jan Albert Kuivenhoven,Philippe Lesnik,Luis Masana,Børge G. Nordestgaard,Kausik K. Ray,Zeljko Reiner,Marja-Riitta Taskinen,Lale Tokgozoglu,Anne Tybjærg-Hansen,Gerald F. Watts +18 more