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On the generation of free radical species from quantum dots.

Binil Itty Ipe, +2 more
- 01 Jul 2005 - 
- Vol. 1, Iss: 7, pp 706-709
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This article is published in Small.The article was published on 2005-07-01. It has received 338 citations till now. The article focuses on the topics: Quantum dot & Electron paramagnetic resonance.

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Bioconjugated quantum dots for in vivo molecular and cellular imaging

TL;DR: The synthesis and development of state-of-the-art QD probes and their use for molecular and cellular imaging are discussed and key issues for in vivo imaging and therapy, such as nanoparticle biodistribution, pharmacokinetics, and toxicology are examined.
Journal ArticleDOI

Nanotechnology Applications in Cancer

TL;DR: Developments in bioaffinity nanoparticle probes for molecular and cellular imaging, targeted nanoparticle drugs for cancer therapy, and integrated nanodevices for early cancer detection and screening raise exciting opportunities for personalized oncology in which genetic and protein biomarkers are used to diagnose and treat cancer based on the molecular profiles of individual patients.
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Multimodality Imaging Probes: Design and Challenges

TL;DR: This review provides an overview of the many strategies that have been applied to achieve multimodal functionality in a single probe unit and the caveat is that because the sensitivities of different imaging modalities can vary by 3 orders of magnitude, it may not be practical to simply add all functionalities to one molecule.
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The cytotoxicity of cadmium-based quantum dots

TL;DR: Recent progress on mechanistic studies of cytotoxicity of II-IV QDs are summarized to suggest that the cytot toxicity of CdTe QDs not only comes from the release of C d(2+) ions but also intracellular distribution of QD nanoparticles in cells and the associated nanoscale effects.
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Long-Term Exposure to CdTe Quantum Dots Causes Functional Impairments in Live Cells

TL;DR: For the various CdTe QD samples, there was no dose-dependent correlation between cell viability and intracellular [Cd2+], implying that their cytotoxicity cannot be attributed solely to the toxic effect of free Cd2+.
References
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Journal ArticleDOI

Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics

TL;DR: The new generations of qdots have far-reaching potential for the study of intracellular processes at the single-molecule level, high-resolution cellular imaging, long-term in vivo observation of cell trafficking, tumor targeting, and diagnostics.
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(CdSe)ZnS Core-Shell Quantum Dots - Synthesis and Characterization of a Size Series of Highly Luminescent Nanocrystallites

TL;DR: In this paper, a synthesis of highly luminescent (CdSe)ZnS composite quantum dots with CdSe cores ranging in diameter from 23 to 55 A was reported.
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Probing the Cytotoxicity Of Semiconductor Quantum Dots.

TL;DR: This work found that CdSe-core QDs were indeed acutely toxic under certain conditions and modulated by processing parameters during synthesis, exposure to ultraviolet light, and surface coatings, and suggests that cytotoxicity correlates with the liberation of free Cd2+ ions due to deterioration of the Cd Se lattice.
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The use of nanocrystals in biological detection

TL;DR: The emerging ability to control the patterns of matter on the nanometer length scale can be expected to lead to entirely new types of biological sensors capable of sensing at the single-molecule level in living cells, and capable of parallel integration for detection of multiple signals.
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Formation of high-quality CdTe, CdSe, and CdS nanocrystals using CdO as precursor.

TL;DR: This paper proves that Cd(CH3)2 can be replaced by CdO and develops a one-pot synthesis which does not require separated preparation of cadmium complex and is reproducible and simple and thus can be readily scaled up for industrial production.
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