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Oxidative stress in Perna perna and other bivalves as indicators of environmental stress in the Brazilian marine environment: antioxidants, lipid peroxidation and DNA damage.

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TLDR
This review summarizes the data obtained in some studies carried out in bivalves from the Brazilian coast subjected to different stress conditions, including the exposure to different contaminants in the laboratory and in the field.
Abstract
Oxidative stress can take place in marine bivalves under a series of environmental adverse conditions. The study of different systems related to oxidative stress in these organisms can give important information about their physiological status and also about environmental health. Bivalves have been proposed as good sentinel organisms in pollution monitoring studies through the analysis of biochemical biomarkers, and most of the biomarkers analyzed are those related to oxidative stress. However, it is very important to know how other environmental factors not associated to the presence of pollutants might affect these parameters. We have studied a series of mechanisms related to oxidative stress in mussels which inhabit the Brazilian coast, especially in Perna perna species, subjected to different stress conditions, such as the exposure to different contaminants in the laboratory and in the field, the exposure of mussels to air and re-submersion, simulating the tidal oscillations, and in mussels collected at different seasons. Both oxidative damage levels and antioxidant defense systems were strongly affected by the different environmental stress. This review summarizes the data obtained in some studies carried out in bivalves from the Brazilian coast.

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Journal ArticleDOI

Antioxidant defenses and oxidative stress parameters in tissues of mud crab (Scylla serrata) with reference to changing salinity.

TL;DR: The results suggest that salinity modulation of oxidative stress and antioxidant defenses in Scylla serrata is tissue specific.
Journal ArticleDOI

Bioaccumulation, cytotoxicity and oxidative stress of the acute exposure selenium in Oreochromis mossambicus.

TL;DR: Assessment of environmentally relevant concentrations of Se toxicity in Mozambique tilapia, Oreochromis mossambicus showed that Se accumulation was observed in the gill, liver and brain tissues of fish exposed to different concentrations and accumulation varied upon different tissues.
Journal ArticleDOI

From molecules to living systems: historical and contemporary issues in oxidative stress and antioxidant ecology

TL;DR: In this paper, an overview of the biochemical basis and conceptual frameworks behind oxidative stress and antioxidants, the research questions and hypotheses that are generated by incorporating antioxidants and oxidative stress into models of life-history theory, ageing, mate selection, and honest signalling, and the trends in the evidence that have emerged from initial studies in these areas.
Journal ArticleDOI

Effects of the model PAH phenanthrene on immune function and oxidative stress in the haemolymph of the temperate scallop Pecten maximus.

TL;DR: This is the first instance where oxidative stress and immune function have been measured together in the haemolymph of a bivalve mollusc, demonstrating a possible link between PAH-induced oxidative Stress and the subsequent inhibition in haemocyte immune function.
References
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Journal ArticleDOI

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes.

TL;DR: This review provides a comprehensive summary on the chemical properties of 4-hydroxyalkenals and malonaldehyde, the mechanisms of their formation and their occurrence in biological systems and methods for their determination, as well as the many types of biological activities described so far.
Journal ArticleDOI

Oxidative stress: oxidants and antioxidants

TL;DR: These low molecular mass antioxidant molecules add significantly to the defense provided by the enzymes superoxide dismutase, catalase and glutathione peroxidases, which are termed ‘oxidative stress’.
Journal ArticleDOI

Reactive Oxygen Species and the Central Nervous System

TL;DR: The nature of antioxidants is discussed, it being suggested that antioxidant enzymes and chelators of transition metal ions may be more generally useful protective agents than chain‐breaking antioxidants.
Journal ArticleDOI

The reaction of no with superoxide

TL;DR: The rate constant for the reaction of NO with .O2- was determined to be (6.7 +/- 0.9) x 10(9) l mol-1 s-1, considerably higher than previously reported.
Journal ArticleDOI

Strategies of antioxidant defense

TL;DR: Cellular protection against the deleterious effects of reactive oxidants generated in aerobic metabolism, called oxidative stress, is organized at multiple levels.
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