Journal ArticleDOI
Physiopathological mechanism of sarcopenia
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TLDR
A multimodal approach combining nutrition, exercise, hormones, and specific anabolic drugs may be an innovative treatment for limiting the development of sarcopenia with aging.About:
This article is published in Clinics in Geriatric Medicine.The article was published on 2011-08-01. It has received 233 citations till now. The article focuses on the topics: Sarcopenia & Protein digestion.read more
Citations
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Journal ArticleDOI
Evidence-Based Recommendations for Optimal Dietary Protein Intake in Older People: A Position Paper From the PROT-AGE Study Group
Juergen M. Bauer,Gianni Biolo,Tommy Cederholm,Matteo Cesari,Alfonso J. Cruz-Jentoft,John E. Morley,Stuart M. Phillips,Cornel C. Sieber,Peter Stehle,Daniel Teta,Renuka Visvanathan,Elena Volpi,Yves Boirie +12 more
TL;DR: To help older people (>65 years) maintain and regain lean body mass and function, the PROT-AGE study group recommends average daily intake at least in the range of 1.2 g protein per kilogram of body weight per day.
Journal ArticleDOI
Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN Expert Group
Nicolaas E. P. Deutz,Jürgen M. Bauer,Rocco Barazzoni,Gianni Biolo,Yves Boirie,Anja Bosy-Westphal,Tommy Cederholm,Tommy Cederholm,Alfonso J. Cruz-Jentoft,Zeljko Krznaric,K. Sreekumaran Nair,Pierre Singer,Daniel Teta,Kevin D. Tipton,Philip C. Calder,Philip C. Calder +15 more
TL;DR: Recommendations are made that daily physical activity or exercise (resistance training, aerobic exercise) should be undertaken by all older people, for as long as possible to help older adults sustain muscle strength and function into older age.
Journal ArticleDOI
Sarcopenia With Limited Mobility: An International Consensus
John E. Morley,Angela Marie Abbatecola,Josep M. Argilés,Vickie E. Baracos,Juergen M. Bauer,Shalender Bhasin,Tommy Cederholm,Andrew J.S. Coats,Steven R. Cummings,William J. Evans,Kenneth C. H. Fearon,Luigi Ferrucci,Roger A. Fielding,Jack M. Guralnik,Tamara B. Harris,Akio Inui,Kamyar Kalantar-Zadeh,Bridget Anne Kirwan,Giovanni Mantovani,Maurizio Muscaritoli,Anne B. Newman,Filippo Rossi-Fanelli,Giuseppe M.C. Rosano,Ronenn Roubenoff,Morris Schambelan,Gerald H. Sokol,Thomas W. Storer,Bruno Vellas,Stephan von Haehling,Shing Shing Yeh,Stefan D. Anker +30 more
TL;DR: It is concluded that "Sarcopenia, ie, reduced muscle mass, with limited mobility" should be considered an important clinical entity and that most older persons should be screened for this condition.
Journal ArticleDOI
Frailty Assessment in the Cardiovascular Care of Older Adults
Jonathan Afilalo,Karen P. Alexander,Michael J. Mack,Mathew S. Maurer,Philip Green,Larry A. Allen,Jeffrey J. Popma,Luigi Ferrucci,Daniel E. Forman +8 more
TL;DR: This work sought to synthesize the existing body of evidence and offer a perspective on how to integrate frailty into clinical practice and contribute valuable prognostic insights incremental to existing risk models and assists clinicians in defining optimal care pathways for their patients.
Journal ArticleDOI
Protein Ingestion to Stimulate Myofibrillar Protein Synthesis Requires Greater Relative Protein Intakes in Healthy Older Versus Younger Men
Daniel R. Moore,Tyler A. Churchward-Venne,Oliver C. Witard,Leigh Breen,Nicholas A. Burd,Kevin D. Tipton,Stuart M. Phillips +6 more
TL;DR: The data suggest that healthy older men are less sensitive to low protein intakes and require a greater relative protein intake, in a single meal, than young men to maximally stimulate postprandial rates of MPS.
References
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Ali H. Mokdad,Earl S. Ford,Barbara A. Bowman,William H. Dietz,Frank Vinicor,Virginia S Bales,James S. Marks +6 more
TL;DR: Overweight and obesity were significantly associated with diabetes, high blood pressure, high cholesterol, asthma, arthritis, and poor health status, and increases in obesity and diabetes continue in both sexes, all ages, all races, all educational levels, and all smoking levels.
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Inflammation, stress, and diabetes
TL;DR: The molecular and cellular underpinnings of obesity-induced inflammation and the signaling pathways at the intersection of metabolism and inflammation that contribute to diabetes are discussed.
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The continuing epidemics of obesity and diabetes in the United States.
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Related Papers (5)
Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia.
Roger A. Fielding,Bruno Vellas,William J. Evans,Shalender Bhasin,John E. Morley,Anne B. Newman,Gabor Abellan van Kan,Sandrine Andrieu,Juergen M. Bauer,Denis Breuille,Tommy Cederholm,Julie Chandler,Capucine De Meynard,Lorenzo M. Donini,Tamara B. Harris,Aimo Kannt,Florence Keime Guibert,Graziano Onder,Dimitris Papanicolaou,Yves Rolland,Daniel Rooks,Cornel C. Sieber,Elisabeth Souhami,Sjors Verlaan,Mauro Zamboni +24 more