Journal ArticleDOI
Plasmonic biosensors for bacterial endotoxin detection on biomimetic C-18 supported fiber optic probes.
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TLDR
An antibiotic-mediated plasmonic biosensor for LPS detection based on a facile U-bent fiber optic probe (UFOP) technology was found to be highly specific in the presence of common biopharmaceutical components and could serve as an efficient endotoxin detection platform for quality control testing during therapeutic development.About:
This article is published in Biosensors and Bioelectronics.The article was published on 2019-03-15. It has received 44 citations till now. The article focuses on the topics: Biosensor.read more
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Fiber-Optic Chemical Sensors and Biosensors (2015-2019).
Xu-dong Wang,Otto S. Wolfbeis +1 more
TL;DR: Fiber optic sensing technology has become mature because of acceptable costs, compact instrumentation, high accuracy and the capability of performing measurements at inaccessible sites, over large distances, in strong (electro) magnetic fields and in harsh environment.
Journal ArticleDOI
HER2 breast cancer biomarker detection using a sandwich optical fiber assay
Médéric Loyez,Maxime Lobry,Eman M. Hassan,Maria C. DeRosa,Christophe Caucheteur,Ruddy Wattiez +5 more
TL;DR: Recent findings about the detection of breast cancer HER2 biomarkers through OF-SPR optrodes are presented and it is believed that these results harbinger the way for their further use in biomedical samples.
Journal ArticleDOI
P-FAB: A Fiber-Optic Biosensor Device for Rapid Detection of COVID-19
TL;DR: This work proposes to exploit the field-deployable/portable plasmonic fiber-optic absorbance biosensor (P-FAB) platform for one-step, wash-free detection of SARS-CoV-2 virus particles directly in saliva sample with minimal sample pre-processing.
Journal ArticleDOI
Recent Progress in Optical Sensors for Biomedical Diagnostics.
Muqsit Pirzada,Zeynep Altintas +1 more
TL;DR: The recent trends discussed in this review hold enormous potential for the widespread use of optical sensors in early-stage disease prediction and point-of-care testing devices.
Journal ArticleDOI
MXene Coupled with CRISPR-Cas12a for Analysis of Endotoxin and Bacteria.
TL;DR: In this article, a new universal analytical method based on MXene coupled with CRISPR-Cas12a was proposed. But the method is limited to detection of LPS and Gram-negative bacteria.
References
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Controlled nucleation for the regulation of the particle size in monodisperse gold suspensions
TL;DR: In this article, a series of monodisperse suspensions of the same chemical composition but of rather different particle sizes was used to study particle size dependent phenomena, such as Brownian motion, light scattering, sedimentation and electrophoresis of small particles.
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Severe sepsis and septic shock
Derek C. Angus,Tom van der Poll +1 more
TL;DR: A review of the basis, diagnosis, and current treatment of Sepsis in patients with this disorder is examined.
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Wet Chemical Synthesis of High Aspect Ratio Cylindrical Gold Nanorods
TL;DR: Gold nanorods with aspect ratios of 4.6 ± 1.2, 13 ± 2, and 18 ± 2.5 are prepared by a seeding growth approach in the presence of an aqueous miceller template.
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Structure—Activity Relationships of Polymyxin Antibiotics
TL;DR: This research presents a novel and scalable approaches that allow for real-time decision-making in the design and implementation of drug 505(b) agonist regimens for the treatment of central nervous system disorders.
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Biosynthesis and Export of Bacterial Lipopolysaccharides
Chris Whitfield,M. Stephen Trent +1 more
TL;DR: This work reviews recent advances in the processes used for lipopolysaccharide biosynthesis and export, emphasizing the reactions that are essential for viability.