Journal ArticleDOI
Polymalic acid fermentation by Aureobasidium pullulans for malic acid production from soybean hull and soy molasses: Fermentation kinetics and economic analysis
TLDR
Polymalic acid production by Aureobasidium pullulans ZX-10 from soybean hull hydrolysate supplemented with corn steep liquor (CSL) gave a malic acid yield of 0.4g/g at a productivity of ∼0.5g/L·h, which offers an economically competitive process for industrial production of bio-based malic Acid.About:
This article is published in Bioresource Technology.The article was published on 2017-01-01. It has received 81 citations till now. The article focuses on the topics: Soy molasses & Malic acid.read more
Citations
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Bio-Based Packaging: Materials, Modifications, Industrial Applications and Sustainability.
Corina L. Reichert,Elodie Bugnicourt,Maria Beatrice Coltelli,Patrizia Cinelli,Andrea Lazzeri,Ilaria Canesi,Francesca Braca,Belén Monje Martínez,Rafael Alonso,Lodovico Agostinis,Steven Verstichel,Lasse Six,Steven De Mets,Elena Cantos Gómez,Constance Ißbrücker,Ruben Geerinck,David F. Nettleton,Inmaculada Campos,Erik Sauter,Pascal Pieczyk,Markus Schmid +20 more
TL;DR: This review is to summarize synthetic and non-synthetic materials feasible for packaging and textile applications, routes of upscaling, industrial applications, evaluation of sustainability, and end-of-life options.
Journal ArticleDOI
Malic acid production from renewables: A review
TL;DR: Out of the alternative substrates discussed in this review, the industrial side‐streams crude glycerol and molasses seem to be most promising for large‐scale l‐malic acid production.
Journal ArticleDOI
A review on versatile applications of blends and composites of pullulan with natural and synthetic polymers.
Shazia Tabasum,Aqdas Noreen,Muhammad Farzam Maqsood,Hijab Umar,Nadia Akram,Zill-i-Huma Nazli,Shahzad Ali Shahid Chatha,Khalid Mahmood Zia +7 more
TL;DR: A comprehensive overview of combination of pullulan with natural and synthetic polymers and their applications in biomedical field involving drug delivery system, tissue engineering, wound healing and gene therapy, is presented.
Journal ArticleDOI
Current advance in biological production of malic acid using wild type and metabolic engineered strains
Zhongxue Dai,Huiyuan Zhou,Shangjie Zhang,Honglian Gu,Qiao Yang,Wenming Zhang,Weiliang Dong,Jiangfeng Ma,Fang Yan,Min Jiang,Fengxue Xin +10 more
TL;DR: This review comprehensively introduces an overview of malic acid producers and highlight some of the successful metabolic engineering approaches.
Journal ArticleDOI
Covalent nano delivery systems for selective imaging and treatment of brain tumors.
Julia Y. Ljubimova,Tao Sun,Leila A Mashouf,Alexander V. Ljubimov,Liron L. Israel,Vladimir A. Ljubimov,Vida Falahatian,Eggehard Holler +7 more
TL;DR: This review attempts to cover the benefits and the limitations of current nanomedicines with special attention to covalent nano conjugates for imaging and drug delivery in the brain.
References
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Journal ArticleDOI
Carbon catabolite repression in bacteria: many ways to make the most out of nutrients
Boris Görke,Jörg Stülke +1 more
TL;DR: The most recent findings on the different mechanisms that have evolved to allow bacteria to use carbon sources in a hierarchical manner are discussed.
Journal ArticleDOI
Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae
Michaela Conrad,Joep Schothorst,Harish Nag Kankipati,Griet Van Zeebroeck,Marta Rubio-Texeira,Johan M. Thevelein +5 more
TL;DR: The yeast Saccharomyces cerevisiae has been a favorite organism for pioneering studies on nutrient-sensing and signaling mechanisms, and its discovery of nutrient transceptors (transporter receptors) as nutrient sensors has led to important new concepts and insight into nutrient-controlled cellular regulation.
Journal ArticleDOI
Malic acid production by Saccharomyces cerevisiae: engineering of pyruvate carboxylation, oxaloacetate reduction, and malate export.
Rintze M. Zelle,Erik de Hulster,Wouter A. van Winden,Pieter de Waard,Cor Dijkema,Aaron Adriaan Winkler,Jan-Maarten A. Geertman,Johannes P. van Dijken,Jack T. Pronk,Antonius J. A. van Maris +9 more
TL;DR: Metabolic flux analysis showed that metabolite labeling patterns observed upon nuclear magnetic resonance analyses of cultures grown on 13C-labeled glucose were consistent with the envisaged nonoxidative, fermentative pathway for malate production.
Journal ArticleDOI
Biotechnological strategies to overcome inhibitors in lignocellulose hydrolysates for ethanol production: review.
Wilson Parawira,Memory Tekere +1 more
TL;DR: This review describes the application and/or effect of biological detoxification (removal of inhibitors before fermentation) or use of bioreduction capability of fermenting yeasts on the fermentability of the hydrolysates and suggests adaptation of the fermentation yeasts to the lignocellulosic hydrolysate prior to fermentation as an alternative approach to detoxification.
Journal ArticleDOI
Combining metabolic engineering and metabolic evolution to develop nonrecombinant strains of Escherichia coli C that produce succinate and malate.
Kaemwich Jantama,Mark John Haupt,Spyros A. Svoronos,Xueli Zhang,Jonathan C. Moore,Keelnatham T. Shanmugam,Lonnie O. Ingram +6 more
TL;DR: Derivatives of Escherichia coli C were engineered to produce primarily succinate or malate in mineral salts media using simple fermentations (anaerobic stirred batch with pH control) without the addition of plasmids or foreign genes by combination of gene deletions and metabolic evolution.