Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: findings from the Hertfordshire Cohort Study (HCS)
Harnish P. Patel,Holly E. Syddall,Karen A. Jameson,Sian M. Robinson,Hayley J Denison,Helen C. Roberts,Mark H. Edwards,Elaine M. Dennison,Cyrus Cooper,Avan Aihie Sayer +9 more
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TLDR
The EWGSOP consensus definition was of practical use for sarcopenia case finding and the next step is to use this consensus definition in other ageing cohorts and among older people in a range of health-care settings.Abstract:
Introduction: sarcopenia is associated with adverse health outcomes. The aim of this study was to describe the prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) consensus definition.
Methods: we applied the EWGSOP definition to 103 community-dwelling men participating in the Hertfordshire Sarcopenia Study (HSS) using both the lowest third of dual-energy X-ray absorptiometry (DXA) lean mass (LM) and the lowest third of skin-fold-based fat-free mass (FFM) as markers of low muscle mass. We also used the FFM approach among 765 male and 1,022 female participants in the Hertfordshire Cohort Study (HCS). Body size, physical performance and self-reported health were compared in participants with and without sarcopenia.
Results: the prevalence of sarcopenia in HSS men (mean age 73 years) was 6.8% and 7.8% when using the lowest third of DXA LM and FFM, respectively. DXA LM and FFM were highly correlated (0.91, P < 0.001). The prevalence of sarcopenia among the HCS men and women (mean age 67 years) was 4.6% and 7.9%, respectively. HSS and HCS participants with sarcopenia were shorter, weighed less and had worse physical performance. HCS men and women with sarcopenia had poorer self-reported general health and physical functioning scores.
Conclusions: this is one of the first studies to describe the prevalence of sarcopenia in UK community-dwelling older people. The EWGSOP consensus definition was of practical use for sarcopenia case finding. The next step is to use this consensus definition in other ageing cohorts and among older people in a range of health-care settings.read more
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Prevalence and Risk Factors of Sarcopenia among Older Adults Aged ≥65 Years Admitted to Daycare Centers of Taiwan: Using AWGS 2019 Guidelines.
TL;DR: Wang et al. as mentioned in this paper found that sarcopenia is a geriatric syndrome which is likely to cause disability, body unbalance, and mortality and thus can lead to heavy healthcare expenditure and caregiver burden.
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Shu Ran,Zi-Xuan Jiang,Xiao He,Yu Liu,Yu-Xue Zhang,Lei Zhang,Yu-Fang Pei,Meng Zhang,Rong Hai,Gui-Shan Gu,Baolin Liu,Qing Tian,Yonghong Zhang,Jing-Yu Wang,Hong-Wen Deng +14 more
TL;DR: There is suggestive evidence that FTO gene is associated with lean mass, and 29 single nucleotide polymorphisms in FTO significantly associated with sarcopenia are found.
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Does Use of Androgen Deprivation Therapy (ADT) in Men with Prostate Cancer Increase the Risk of Sarcopenia
Patrick J. Owen,Robin M. Daly,Jack Dalla Via,Niamh L Mundell,Patricia M. Livingston,Timo Rantalainen,Timo Rantalainen,Steve F. Fraser +7 more
TL;DR: Overall the prevalence of sarcopenia was low and did not differ between the three groups, and an adiposity-based adjustment of ALM is recommended to quantify risk of adverse outcomes associated with ADT in these men.
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Independent Association Between Cardio‐Ankle Vascular Index and Sarcopenia in Older U.K. Adults
Frances A. Kirkham,Eva Bunting,Eva Bunting,Francesco Fantin,Mauro Zamboni,Chakravarthi Rajkumar,Chakravarthi Rajkumar +6 more
TL;DR: To investigate the correlation between sarcopenia and arterial stiffness in Caucasians, centering on the relationship between skeletal mass index (SMI) and the cardio‐ankle vascular index (CAVI) to assess the use of CAVI in predicting sarc Openia.
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Electromyographic and Safety Comparisons of Common Lower Limb Rehabilitation Exercises for People With Hemophilia.
Joaquin Calatayud,Sofía Pérez-Alenda,Juan J Carrasco,Adrian Escriche-Escuder,Carlos Cruz-Montecinos,Lars L. Andersen,Santiago Bonanad,Felipe Querol,José Casaña +8 more
TL;DR: Exercises performed both with elastic bands and with machines at moderate intensity are safe, feasible, and efficient in people with severe hemophilia, providing comparable activity levels in the agonist muscles.
References
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Richard N. Baumgartner,Kathleen M. Koehler,Dympna Gallagher,Linda J. Romero,Steven B. Heymsfield,Robert Ross,Philip J. Garry,Robert D. Lindeman +7 more
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Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia.
Roger A. Fielding,Bruno Vellas,William J. Evans,Shalender Bhasin,John E. Morley,Anne B. Newman,Gabor Abellan van Kan,Sandrine Andrieu,Juergen M. Bauer,Denis Breuille,Tommy Cederholm,Julie Chandler,Capucine De Meynard,Lorenzo M. Donini,Tamara B. Harris,Aimo Kannt,Florence Keime Guibert,Graziano Onder,Dimitris Papanicolaou,Yves Rolland,Daniel Rooks,Cornel C. Sieber,Elisabeth Souhami,Sjors Verlaan,Mauro Zamboni +24 more
TL;DR: Sarcopenia should be considered in all older patients who present with observed declines in physical function, strength, or overall health, and patients who meet these criteria should further undergo body composition assessment using dual energy x-ray absorptiometry with sarcopenia being defined using currently validated definitions.
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