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Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: findings from the Hertfordshire Cohort Study (HCS)

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TLDR
The EWGSOP consensus definition was of practical use for sarcopenia case finding and the next step is to use this consensus definition in other ageing cohorts and among older people in a range of health-care settings.
Abstract
Introduction: sarcopenia is associated with adverse health outcomes. The aim of this study was to describe the prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) consensus definition. Methods: we applied the EWGSOP definition to 103 community-dwelling men participating in the Hertfordshire Sarcopenia Study (HSS) using both the lowest third of dual-energy X-ray absorptiometry (DXA) lean mass (LM) and the lowest third of skin-fold-based fat-free mass (FFM) as markers of low muscle mass. We also used the FFM approach among 765 male and 1,022 female participants in the Hertfordshire Cohort Study (HCS). Body size, physical performance and self-reported health were compared in participants with and without sarcopenia. Results: the prevalence of sarcopenia in HSS men (mean age 73 years) was 6.8% and 7.8% when using the lowest third of DXA LM and FFM, respectively. DXA LM and FFM were highly correlated (0.91, P < 0.001). The prevalence of sarcopenia among the HCS men and women (mean age 67 years) was 4.6% and 7.9%, respectively. HSS and HCS participants with sarcopenia were shorter, weighed less and had worse physical performance. HCS men and women with sarcopenia had poorer self-reported general health and physical functioning scores. Conclusions: this is one of the first studies to describe the prevalence of sarcopenia in UK community-dwelling older people. The EWGSOP consensus definition was of practical use for sarcopenia case finding. The next step is to use this consensus definition in other ageing cohorts and among older people in a range of health-care settings.

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DissertationDOI

Associação entre sarcopenia com variáveis de qualidade de vida em idosos quilombolas

Silva Neto, +1 more
TL;DR: The present results showed that diagnostic criteria for sarcopenia should include reductions in lean mass in addition to measures of functioning and physical performance, since some subjects showed the former symptom without any alteration of the latter two variables.
Journal ArticleDOI

Prevalence of sarcopenia in elderly users of the primary health care system

TL;DR: Results show the importance of assessing nutritional status and a potential diagnosis of sarcopenia, mainly since this syndrome is highly associated with inappropriate food intake, which is often impaired among the elderly because of economical and/or physiological reasons.
Dissertation

Frailty, sarcopenia and immunesenescence: shared mechanisms and clinical insights

Daisy Wilson
TL;DR: Incubation of neutrophils from frail older adults with PI3kinase inhibitors class 1A \(\delta\) and class lB y restored migratory accuracy and this presents a novel therapeutic target for management of frailty.
Journal ArticleDOI

Management of Sarcopenia to Improve Quality of Life in Geriatric Populations

TL;DR: Well-designed exercise interventions, particularly resistance training as well as nutritional supplementation, have been proved to improve muscle strength and performance in geriatric populations and resistance training may also enhance quality of life.
References
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Journal ArticleDOI

Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years

TL;DR: Skinfold thicknesses at four sites – biceps, triceps, subscapular and supra-iliac – and total body density were measured on 209 males and 272 females aged from 16 to 72 years, finding it necessary to use the logarithm of skinfold measurements in order to achieve a linear relationship with body density.
Journal ArticleDOI

Epidemiology of Sarcopenia among the Elderly in New Mexico

TL;DR: Some of the first estimates of the extent of the public health problem posed by sarcopenia are provided, independent of ethnicity, age, morbidity, obesity, income, and health behaviors.
Journal ArticleDOI

Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability.

TL;DR: To establish the prevalence of sarc Openia in older Americans and to test the hypothesis that sarcopenia is related to functional impairment and physical disability in older persons is established.
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