Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: findings from the Hertfordshire Cohort Study (HCS)
Harnish P. Patel,Holly E. Syddall,Karen A. Jameson,Sian M. Robinson,Hayley J Denison,Helen C. Roberts,Mark H. Edwards,Elaine M. Dennison,Cyrus Cooper,Avan Aihie Sayer +9 more
Reads0
Chats0
TLDR
The EWGSOP consensus definition was of practical use for sarcopenia case finding and the next step is to use this consensus definition in other ageing cohorts and among older people in a range of health-care settings.Abstract:
Introduction: sarcopenia is associated with adverse health outcomes. The aim of this study was to describe the prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) consensus definition.
Methods: we applied the EWGSOP definition to 103 community-dwelling men participating in the Hertfordshire Sarcopenia Study (HSS) using both the lowest third of dual-energy X-ray absorptiometry (DXA) lean mass (LM) and the lowest third of skin-fold-based fat-free mass (FFM) as markers of low muscle mass. We also used the FFM approach among 765 male and 1,022 female participants in the Hertfordshire Cohort Study (HCS). Body size, physical performance and self-reported health were compared in participants with and without sarcopenia.
Results: the prevalence of sarcopenia in HSS men (mean age 73 years) was 6.8% and 7.8% when using the lowest third of DXA LM and FFM, respectively. DXA LM and FFM were highly correlated (0.91, P < 0.001). The prevalence of sarcopenia among the HCS men and women (mean age 67 years) was 4.6% and 7.9%, respectively. HSS and HCS participants with sarcopenia were shorter, weighed less and had worse physical performance. HCS men and women with sarcopenia had poorer self-reported general health and physical functioning scores.
Conclusions: this is one of the first studies to describe the prevalence of sarcopenia in UK community-dwelling older people. The EWGSOP consensus definition was of practical use for sarcopenia case finding. The next step is to use this consensus definition in other ageing cohorts and among older people in a range of health-care settings.read more
Citations
More filters
Journal ArticleDOI
Sarcopenia Is Associated With Physical and Mental Components of Health-Related Quality of Life in Older Adults.
Betty Manrique-Espinoza,Aarón Salinas-Rodríguez,Oscar Rosas-Carrasco,Luis Miguel Gutiérrez-Robledo,José Alberto Avila-Funes +4 more
TL;DR: The results on the association between sarcopenia and HRQoL suggest that the latter declines in the presence of severe sarc Openia in older adults, highlighting the relevance of the early detection of sarcopenIA in older individuals.
Journal ArticleDOI
Ethnic and geographic variations in muscle mass, muscle strength and physical performance measures
Jean Woo,Hidenori Arai,T.P. Ng,Avan Aihie Sayer,M. Wong,Holly E. Syddall,Minoru Yamada,P. Zeng,S. Wu,T.M. Zhang +9 more
TL;DR: There was considerable variation in mean values in body mass index, appendicular skeletal mass index (ASM/ht2), grip strength, walking speed between different Asian ethnic groups, and also between same ethnic groups living in different geographic locations.
Journal ArticleDOI
The Role of Ultrasound as a Diagnostic Tool for Sarcopenia.
TL;DR: This position paper aims to provide a short overview proposing the potential case for developing ultrasound as a new and alternative diagnostic tool for identifying sarcopenia.
Journal ArticleDOI
Relationships Between Markers of Inflammation and Muscle Mass, Strength and Function: Findings from the Hertfordshire Cohort Study
Leo D. Westbury,Nicholas R Fuggle,Holly E. Syddall,Niharika A. Duggal,Sarah Shaw,K Maslin,Elaine M. Dennison,Elaine M. Dennison,Janet M. Lord,Cyrus Cooper,Cyrus Cooper,Cyrus Cooper +11 more
TL;DR: Gender-adjusted linear and Poisson regression was used to examine the associations between inflammation markers and outcomes with and without adjustment for anthropometric and lifestyle factors, and associations were robust in fully-adjusted analyses.
Journal ArticleDOI
microRNAs: Modulators of the underlying pathophysiology of sarcopenia?
TL;DR: The aim of this review is to outline the latest understanding of the pathophysiological alterations impacting the deregulation of skeletal muscle mass and function with ageing, and to highlight the mounting evidence for a role of miRNAs in modulating muscle mass, and the need to explore their specific role in sarcopenia.
References
More filters
Journal ArticleDOI
Sarcopenia: European consensus on definition and diagnosis Report of the European Working Group on Sarcopenia in Older People
Alfonso J. Cruz-Jentoft,Jean-Pierre Baeyens,Jürgen M. Bauer,Yves Boirie,Tommy Cederholm,Francesco Landi,Finbarr C. Martin,Jean-Pierre Michel,Yves Rolland,Stéphane M. Schneider,Eva Topinkova,Maurits Vandewoude,Mauro Zamboni +12 more
TL;DR: The European Working Group on Sarcopenia in Older People (EWGSOP) developed a practical clinical definition and consensus diagnostic criteria for age-related sarcopenia as discussed by the authors.
Journal ArticleDOI
Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years
J. V. G. A. Durnin,J. Womersley +1 more
TL;DR: Skinfold thicknesses at four sites – biceps, triceps, subscapular and supra-iliac – and total body density were measured on 209 males and 272 females aged from 16 to 72 years, finding it necessary to use the logarithm of skinfold measurements in order to achieve a linear relationship with body density.
Journal ArticleDOI
Epidemiology of Sarcopenia among the Elderly in New Mexico
Richard N. Baumgartner,Kathleen M. Koehler,Dympna Gallagher,Linda J. Romero,Steven B. Heymsfield,Robert Ross,Philip J. Garry,Robert D. Lindeman +7 more
TL;DR: Some of the first estimates of the extent of the public health problem posed by sarcopenia are provided, independent of ethnicity, age, morbidity, obesity, income, and health behaviors.
Journal ArticleDOI
Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability.
TL;DR: To establish the prevalence of sarc Openia in older Americans and to test the hypothesis that sarcopenia is related to functional impairment and physical disability in older persons is established.
Journal ArticleDOI
Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia.
Roger A. Fielding,Bruno Vellas,William J. Evans,Shalender Bhasin,John E. Morley,Anne B. Newman,Gabor Abellan van Kan,Sandrine Andrieu,Juergen M. Bauer,Denis Breuille,Tommy Cederholm,Julie Chandler,Capucine De Meynard,Lorenzo M. Donini,Tamara B. Harris,Aimo Kannt,Florence Keime Guibert,Graziano Onder,Dimitris Papanicolaou,Yves Rolland,Daniel Rooks,Cornel C. Sieber,Elisabeth Souhami,Sjors Verlaan,Mauro Zamboni +24 more
TL;DR: Sarcopenia should be considered in all older patients who present with observed declines in physical function, strength, or overall health, and patients who meet these criteria should further undergo body composition assessment using dual energy x-ray absorptiometry with sarcopenia being defined using currently validated definitions.
Related Papers (5)
Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia.
Roger A. Fielding,Bruno Vellas,William J. Evans,Shalender Bhasin,John E. Morley,Anne B. Newman,Gabor Abellan van Kan,Sandrine Andrieu,Juergen M. Bauer,Denis Breuille,Tommy Cederholm,Julie Chandler,Capucine De Meynard,Lorenzo M. Donini,Tamara B. Harris,Aimo Kannt,Florence Keime Guibert,Graziano Onder,Dimitris Papanicolaou,Yves Rolland,Daniel Rooks,Cornel C. Sieber,Elisabeth Souhami,Sjors Verlaan,Mauro Zamboni +24 more