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Journal ArticleDOI

Prevention of cardiovascular events with calcium channel blocker-based combination therapies in patients with hypertension: A randomized controlled trial

Masunori Matsuzaki, +16 more
- 01 Aug 2011 - 
- Vol. 29, Iss: 8, pp 1649-1659
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TLDR
CCB combined with ARB, &bgr;-blocker, or thiazide diuretic was similarly effective for the prevention of cardiovascular events and the achievement of target BP.
Abstract: 
ObjectivesCurrent guidelines recommend the use of multiple medications for hypertension. The present study was aimed at determining which combination was optimal to prevent cardiovascular events.MethodsWe conducted a prospective, randomized, open-label, blinded-endpoint trial. Hypertensive outpatien

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Citations
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Journal ArticleDOI

2018 ESC/ESH Guidelines for the management of arterial hypertension.

B. Williams, +27 more
- 01 Sep 2018 - 
Journal ArticleDOI

Guidelines for the Primary Prevention of Stroke A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

Larry B. Goldstein, +17 more
- 01 Feb 2011 - 
TL;DR: Evidence-based recommendations are included for the control of risk factors, interventional approaches to atherosclerotic disease of the cervicocephalic circulation, and antithrombotic treatments for preventing thrombosis and thromboembolic stroke.
Journal ArticleDOI

2018 ESC/ESH Guidelines for the management of arterial hypertension : The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension

Bryan Williams, +27 more
- 01 Oct 2018 - 
TL;DR: De Backer et al. as mentioned in this paper developed the ESC Guidelines for the ESC Review Co-ordinator, which are used for the evaluation of the ESC review process and the review process.
Journal ArticleDOI

2021 ESC Guidelines on cardiovascular disease prevention in clinical practice

Frank L.J. Visseren, +105 more
- 07 Sep 2021 - 
Journal ArticleDOI

The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019)

Satoshi Umemura, +44 more
- 01 Sep 2019 - 
TL;DR: The story of the life and times of Toshihiko Umemura and his family in the years leading up to and including his death.
References
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Journal ArticleDOI

Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure

Aram V. Chobanian, +10 more
- 01 Dec 2003 - 
TL;DR: In those older than age 50, systolic blood pressure of greater than 140 mm Hg is a more important cardiovascular disease (CVD) risk factor than diastolic BP, and hypertension will be controlled only if patients are motivated to stay on their treatment plan.
Journal ArticleDOI

Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial

Lennart Hansson, +9 more
- 13 Jun 1998 - 
TL;DR: Intensive lowering of blood pressure in patients with hypertension was associated with a low rate of cardiovascular events and the potential benefit of a low dose of acetylsalicylic acid in the treatment of hypertension was assessed.
Journal ArticleDOI

Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol.

Björn Dahlöf, +14 more
- 23 Mar 2002 - 
TL;DR: Losartan prevents more cardiovascular morbidity and death than atenolol for a similar reduction in blood pressure and is better tolerated, while new-onset diabetes was less frequent with losartan.
Journal ArticleDOI

Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT)

Curt D. Furberg, +56 more
- 18 Dec 2002 - 
TL;DR: Thiazide-type diuretics are superior in preventing 1 or more major forms of CVD and are less expensive and should be preferred for first-step antihypertensive therapy.
Journal ArticleDOI

Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial

Björn Dahlöf, +13 more
- 10 Sep 2005 - 
TL;DR: The amlodipine-based regimen prevented more major cardiovascular events and induced less diabetes than the atenolol- based regimen, and these effects might not be entirely explained by better control of blood pressure.
Related Papers (5)

2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

Giuseppe Mancia, +89 more
- 21 Jul 2013 - 

Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial

Björn Dahlöf, +13 more
- 10 Sep 2005 - 

Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol.

Björn Dahlöf, +14 more
- 23 Mar 2002 - 

Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT)

Curt D. Furberg, +56 more
- 18 Dec 2002 - 

Telmisartan, Ramipril, or Both in Patients at High Risk for Vascular Events

Koon K. Teo, +6 more
- 10 Apr 2008 -