Journal ArticleDOI
Progress in the mitsunobu reaction. a review
TLDR
A review of progress in the MITSUNOBU this article reaction can be found in this article, with a focus on the MIT SUNOBU reaction and a review of the progress.About:
This article is published in Organic Preparations and Procedures International.The article was published on 1996-04-01. It has received 373 citations till now. The article focuses on the topics: Mitsunobu reaction.read more
Citations
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The teraton challenge. A review of fixation and transformation of carbon dioxide
TL;DR: In this paper, the authors present a review of CO2, its synthetic reactions and their possible role in future CO2 mitigation schemes that have to match the scale of man-made CO2 in the atmosphere, which rapidly approaches 1 teraton.
Journal ArticleDOI
Key green chemistry research areas—a perspective from pharmaceutical manufacturers
David J. C. Constable,Peter J. Dunn,John D. Hayler,Guy R. Humphrey,Johnnie L. Leazer,Russell J. Linderman,Kurt T. Lorenz,Julie B. Manley,Bruce A. Pearlman,Andrew S. Wells,Aleksey Zaks,Tony Y. Zhang +11 more
TL;DR: An assessment of the current state of the art in green chemistry and green engineering areas and to highlight areas for future improvement are provided.
Journal ArticleDOI
Mitsunobu and Related Reactions: Advances and Applications
TL;DR: This review concludes that Etherification without Cyclization and N-Alkylation should be considered as separate science, and the proposed treatment of Etherification with Cyclization as a separate science should be reconsidered.
Journal ArticleDOI
Aspects of carbon dioxide utilization
TL;DR: In this paper, the production of carbon dioxide with metal compounds as catalysts has been studied and further development of these production processes is expected, especially the productions of formic acids, formic acid methyl esters, formamides, methanol, dimethyl carbonate and urethanes with a dialkyltin catalyst.
References
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Journal ArticleDOI
New applications of the mitsunobu reaction in the synthesis of C-2 N-methyl carbapenems
TL;DR: In this paper, N-acyl amides and Nacylamino heterocycles can be reacted regioselectively with C-2 hydroxymethyl carbapenems under Mitsunobu conditions.
Journal ArticleDOI
Mitsunobu Reactions for the Synthesis of Carbocyclic Analogues of Nucleosides: Examination of the Regioselectivity1
TL;DR: In this paper, a general synthetic method for carbocyclic nucleosides, based on the Mitsunobu reaction of purine, pyrimidin-2-one and their substituted derivatives with a variety of alcohols, was presented.
Journal ArticleDOI
General Approach to the Synthesis of Specifically Deuterium-Labeled Nucleosides
TL;DR: These syntheses provide convenient access to millimolar quantities of deuterium/tritium-labeled natural or unnatural nucleosides for direct use or automated oligonucleotide synthesis.
Journal ArticleDOI
Synthesis of monoprotected 2-alkylidene-1,3-propanediols by an unusual SN2′ Mitsunobu reaction
André B. Charette,Bernard Côté +1 more
TL;DR: In this article, a simple and efficient route to monoprotected E -and Z -2-alkylidene-1,3-propanediols was developed, which involves an unusual regio-and stereoselective S N 2′ Mitsunobu reaction of substituted 3-hydroxy-2-methylenealkenoate.
Journal ArticleDOI
S-Adenosyl-L-homocysteine Hydrolase Inhibitors as Anti-Viral Agents: 5′-Deoxyaristeromycin
Suhaib M. Siddiqi,Stewart W. Schneller,Satoru Ikeda,Robert Snoeck,Graciela Andrei,Jan Balzarini,Erik De Clercq +6 more
TL;DR: Compound (-)-3 showed an antiviral activity spectrum characteristic of that of S-adenosyl-L-homocysteine hydrolase inhibitors (such as carbocyclic 3-deazaadenosine and neplanocin A) and was found to possess an IC50 of 3.28 /pm 0.48 μM towards this enzyme.
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