Journal ArticleDOI
Progress in the mitsunobu reaction. a review
TLDR
A review of progress in the MITSUNOBU this article reaction can be found in this article, with a focus on the MIT SUNOBU reaction and a review of the progress.About:
This article is published in Organic Preparations and Procedures International.The article was published on 1996-04-01. It has received 373 citations till now. The article focuses on the topics: Mitsunobu reaction.read more
Citations
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The teraton challenge. A review of fixation and transformation of carbon dioxide
TL;DR: In this paper, the authors present a review of CO2, its synthetic reactions and their possible role in future CO2 mitigation schemes that have to match the scale of man-made CO2 in the atmosphere, which rapidly approaches 1 teraton.
Journal ArticleDOI
Key green chemistry research areas—a perspective from pharmaceutical manufacturers
David J. C. Constable,Peter J. Dunn,John D. Hayler,Guy R. Humphrey,Johnnie L. Leazer,Russell J. Linderman,Kurt T. Lorenz,Julie B. Manley,Bruce A. Pearlman,Andrew S. Wells,Aleksey Zaks,Tony Y. Zhang +11 more
TL;DR: An assessment of the current state of the art in green chemistry and green engineering areas and to highlight areas for future improvement are provided.
Journal ArticleDOI
Mitsunobu and Related Reactions: Advances and Applications
TL;DR: This review concludes that Etherification without Cyclization and N-Alkylation should be considered as separate science, and the proposed treatment of Etherification with Cyclization as a separate science should be reconsidered.
Journal ArticleDOI
Aspects of carbon dioxide utilization
TL;DR: In this paper, the production of carbon dioxide with metal compounds as catalysts has been studied and further development of these production processes is expected, especially the productions of formic acids, formic acid methyl esters, formamides, methanol, dimethyl carbonate and urethanes with a dialkyltin catalyst.
References
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Journal ArticleDOI
A revised mechanism for the Mitsunobu reaction
Journal ArticleDOI
N- vs. O-alkylation in the mitsunobu reaction of 2-pyridone
Daniel L. Comins,Gao Jianhua +1 more
TL;DR: An N- vs. O-alkylation study of 2-pyridone with various alcohols and solvents under Mitsunobu conditions was carried out.
Journal ArticleDOI
N,N,N′,N′-Tetramethylazodicarboxamide(TMAD), A New Versatile Reagent for Mitsunobu Reaction. Its Application to Synthesis of Secondary Amines.
TL;DR: The usefulness of the TMAD reagent was demonstrated by the highly efficient two-step synthesis of benzylcrotylamine from N-benzyltrifluoroacetamide, when used in combination with tributylphosphine in benzene.
Journal ArticleDOI
Formation of Oxazolines and Thiazolines in Peptides by the Mitsunobu Reaction.
TL;DR: The Mitsunobu reaction was efficiently used to introduce oxazolines and thiazolines in the peptide backbone as discussed by the authors, and the reaction proceeded from β-hydroxy αamino acid-containing peptides at room temperature in 58-72% isolated yields.
Journal ArticleDOI
Synthesis and biological evaluation of 4-purinylpyrrolidine nucleosides.
Mark Peterson,Robert Vince +1 more
TL;DR: The synthesis of several novel carbocyclic purine nucleosides that incorporate a nitrogen in place of carbon 3 of the cyclopentyl moiety are described and failed to appreciably inhibit the growth of P388 mouse leukemia cells in vitro at concentrations up to 100 micrograms/mL.
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The Use of Diethyl Azodicarboxylate and Triphenylphosphine in Synthesis and Transformation of Natural Products
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